Immunoresponse to Gene-Modified Hematopoietic Stem Cells

por Drysdale, Claire M., Tisdale, John F., Uchida, Naoya
Publicado 2019

Decitabine Suspends Human CD34(+) Cell Differentiation and Proliferation during Lentiviral Transduction

por Uchida, Naoya, Hsieh, Matthew M., Platner, Charlotte, Saunthararajah, Yogen, Tisdale, John F.
Publicado 2014

Hematopoietic Stem Cell Gene-Addition/Editing Therapy in Sickle Cell Disease

por Germino-Watnick, Paula, Hinds, Malikiya, Le, Anh, Chu, Rebecca, Liu, Xiong, Uchida, Naoya
Publicado 2022

Biallelic correction of sickle cell disease‐derived induced pluripotent stem cells (iPSCs) confirmed at the protein level through serum‐free iPS‐sac/erythroid differentiation

por Haro‐Mora, Juan J., Uchida, Naoya, Demirci, Selami, Wang, Qi, Zou, Jizhong, Tisdale, John F.
Publicado 2020

Large-scale purification of functional AAV particles packaging the full genome using short-term ultracentrifugation with a zonal rotor

por Wada, Mikako, Uchida, Naoya, Posadas-Herrera, Guillermo, Hayashita-Kinoh, Hiromi, Tsunekawa, Yuji, Hirai, Yukihiko, Okada, Takashi
Publicado 2023

Long-Term Vector Integration Site Analysis Following Retroviral Mediated Gene Transfer to Hematopoietic Stem Cells for the Treatment of HIV Infection

por Hayakawa, Jun, Washington, Kareem, Uchida, Naoya, Phang, Oswald, Kang, Elizabeth M., Hsieh, Matthew M., Tisdale, John F.
Publicado 2009

Serum-free Erythroid Differentiation for Efficient Genetic Modification and High-Level Adult Hemoglobin Production

por Uchida, Naoya, Demirci, Selami, Haro-Mora, Juan J., Fujita, Atsushi, Raines, Lydia N., Hsieh, Matthew M., Tisdale, John F.
Publicado 2018

Evaluation of genetic diversity using 31 microsatellites in Miyako horses

por MASUDA, Mioko, NIKADORI, Akihiro, NIKADORI, Emi, UCHIDA, Naoya, TAKIZAWA, Yoshimasa, ISHIMARU, Mutsuki, YAMAMOTO, Takumi, YUASA, Reiko, KUGAI, Haruo, NAGAHAMA, Yukio, TAKASU, Masaki, TOZAKI, Teruaki
Publicado 2023

High-Efficiency Lentiviral Transduction of Human CD34(+) Cells in High-Density Culture with Poloxamer and Prostaglandin E2

por Uchida, Naoya, Nassehi, Tina, Drysdale, Claire M., Gamer, Jackson, Yapundich, Morgan, Demirci, Selami, Haro-Mora, Juan J., Leonard, Alexis, Hsieh, Matthew M., Tisdale, John F.
Publicado 2019

Low-Dose Busulfan Reduces Human CD34(+) Cell Doses Required for Engraftment in c-kit Mutant Immunodeficient Mice

por Leonard, Alexis, Yapundich, Morgan, Nassehi, Tina, Gamer, Jackson, Drysdale, Claire M., Haro-Mora, Juan J., Demirci, Selami, Hsieh, Matthew M., Uchida, Naoya, Tisdale, John F.
Publicado 2019

βT87Q-Globin Gene Therapy Reduces Sickle Hemoglobin Production, Allowing for Ex Vivo Anti-sickling Activity in Human Erythroid Cells

por Demirci, Selami, Gudmundsdottir, Bjorg, Li, Quan, Haro-Mora, Juan J., Nassehi, Tina, Drysdale, Claire, Yapundich, Morgan, Gamer, Jackson, Seifuddin, Fayaz, Tisdale, John F., Uchida, Naoya
Publicado 2020

Total body irradiation must be delivered at high dose for efficient engraftment and tolerance in a rhesus stem cell gene therapy model

por Uchida, Naoya, Weitzel, R Patrick, Shvygin, Anna, Skala, Luke P, Raines, Lydia, Bonifacino, Aylin C, Krouse, Allen E, Metzger, Mark E, Donahue, Robert E, Tisdale, John F
Publicado 2016

Development of a forward-oriented therapeutic lentiviral vector for hemoglobin disorders

por Uchida, Naoya, Hsieh, Matthew M., Raines, Lydia, Haro-Mora, Juan J., Demirci, Selami, Bonifacino, Aylin C., Krouse, Allen E., Metzger, Mark E., Donahue, Robert E., Tisdale, John F.
Publicado 2019

Definitive hematopoietic stem/progenitor cells from human embryonic stem cells through serum/feeder-free organoid-induced differentiation

por Demirci, Selami, Haro-Mora, Juan J., Leonard, Alexis, Drysdale, Claire, Malide, Daniela, Keyvanfar, Keyvan, Essawi, Khaled, Vizcardo, Raul, Tamaoki, Naritaka, Restifo, Nicholas P., Tisdale, John F., Uchida, Naoya
Publicado 2020

Correction to: Definitive hematopoietic stem/progenitor cells from human embryonic stem cells through serum/feeder-free organoid-induced differentiation

por Demirci, Selami, Haro-Mora, Juan J., Leonard, Alexis, Drysdale, Claire, Malide, Daniela, Keyvanfar, Keyvan, Essawi, Khaled, Vizcardo, Raul, Tamaoki, Naritaka, Restifo, Nicholas P., Tisdale, John F., Uchida, Naoya
Publicado 2020

Integration-specific In Vitro Evaluation of Lentivirally Transduced Rhesus CD34(+) Cells Correlates With In Vivo Vector Copy Number

por Uchida, Naoya, Evans, Molly E, Hsieh, Matthew M, Bonifacino, Aylin C, Krouse, Allen E, Metzger, Mark E, Sellers, Stephanie E, Dunbar, Cynthia E, Donahue, Robert E, Tisdale, John F
Publicado 2013

Cas9 protein delivery non-integrating lentiviral vectors for gene correction in sickle cell disease

por Uchida, Naoya, Drysdale, Claire M., Nassehi, Tina, Gamer, Jackson, Yapundich, Morgan, DiNicola, Julia, Shibata, Yoshitaka, Hinds, Malikiya, Gudmundsdottir, Bjorg, Haro-Mora, Juan J., Demirci, Selami, Tisdale, John F.
Publicado 2021

Robust generation of erythroid and multilineage hematopoietic progenitors from human iPSCs using a scalable monolayer culture system

por Ruiz, Juan Pablo, Chen, Guibin, Haro Mora, Juan Jesus, Keyvanfar, Keyvan, Liu, Chengyu, Zou, Jizhong, Beers, Jeanette, Bloomer, Hanan, Qanash, Husam, Uchida, Naoya, Tisdale, John F., Boehm, Manfred, Larochelle, Andre
Publicado 2019

Lovo‐cel gene therapy for sickle cell disease: Treatment process evolution and outcomes in the initial groups of the HGB‐206 study

por Kanter, Julie, Thompson, Alexis A., Pierciey, Francis J., Hsieh, Matthew, Uchida, Naoya, Leboulch, Philippe, Schmidt, Manfred, Bonner, Melissa, Guo, Ruiting, Miller, Alex, Ribeil, Jean‐Antoine, Davidson, David, Asmal, Mohammed, Walters, Mark C., Tisdale, John F.
Publicado 2022

Safe and efficient peripheral blood stem cell collection in patients with sickle cell disease using plerixafor

por Uchida, Naoya, Leonard, Alexis, Stroncek, David, Panch, Sandhya R., West, Kamille, Molloy, Eoghan, Hughes, Thomas E., Hauffe, Sara, Taylor, Tiffani, Fitzhugh, Courtney, Hankins, Jane S., Wilson, Megan, Sharma, Akshay, Tsai, Shengdar Q., Weiss, Mitchell J., Hsieh, Matthew, Tisdale, John F.
Publicado 2020