Advances and challenges in targeting IRF5, a key regulator of inflammation

por Almuttaqi, Hannah, Udalova, Irina A.
Publicado 2018

Synovial single-cell heterogeneity, zonation and interactions: a patchwork of effectors in arthritis

por Schonfeldova, Barbora, Zec, Kristina, Udalova, Irina A
Publicado 2021

IRF5 Is a Specific Marker of Inflammatory Macrophages In Vivo

por Weiss, Miriam, Blazek, Katrina, Byrne, Adam J., Perocheau, Dany P., Udalova, Irina A.
Publicado 2013

Cross-species Analysis Reveals Evolving and Conserved Features of the Nuclear Factor κB (NF-κB) Proteins

por Ryzhakov, Grigory, Teixeira, Ana, Saliba, David, Blazek, Katrina, Muta, Tatsushi, Ragoussis, Jiannis, Udalova, Irina A.
Publicado 2013

A critical role for IRF5 in regulating allergic airway inflammation

por Byrne, Adam J., Weiss, Miriam, Mathie, Sara A., Walker, Simone A., Eames, Hayley L., Saliba, David, Lloyd, Clare M., Udalova, Irina A.
Publicado 2016

Principles of dimer-specific gene regulation revealed by a comprehensive characterization of NF-κB family DNA binding

por Siggers, Trevor, Chang, Abraham B, Teixeira, Ana, Wong, Daniel, Williams, Kevin J, Ahmed, Bilal, Ragoussis, Jiannis, Udalova, Irina A, Smale, Stephen T, Bulyk, Martha L
Publicado 2011

Extensive characterization of NF-κB binding uncovers non-canonical motifs and advances the interpretation of genetic functional traits

por Wong, Daniel, Teixeira, Ana, Oikonomopoulos, Spyros, Humburg, Peter, Lone, Imtiaz Nisar, Saliba, David, Siggers, Trevor, Bulyk, Martha, Angelov, Dimitar, Dimitrov, Stefan, Udalova, Irina A, Ragoussis, Jiannis
Publicado 2011

IFN-λ resolves inflammation via suppression of neutrophil infiltration and IL-1β production

por Blazek, Katrina, Eames, Hayley L., Weiss, Miriam, Byrne, Adam J., Perocheau, Dany, Pease, James E., Doyle, Sean, McCann, Fiona, Williams, Richard O., Udalova, Irina A.
Publicado 2015

Macrophages in the synovial lining niche initiate neutrophil recruitment and articular inflammation

por Zec, Kristina, Schonfeldova, Barbora, Ai, Zhichao, Van Grinsven, Erinke, Pirgova, Gabriela, Eames, Hayley L., Berthold, Dorothée L., Attar, Moustafa, Compeer, Ewoud B., Arnon, Tal I., Udalova, Irina A.
Publicado 2023

Antibody response to homologous epitopes of Epstein-Barr virus, Mycobacterium avium subsp. paratuberculosis and IRF5 in patients with different connective tissue diseases and in mo...

por Bo, Marco, Niegowska, Magdalena, Eames, Hayley L., Almuttaqi, Hannah, Arru, Giannina, Erre, Gian Luca, Passiu, Giuseppe, Khoyratty, Tariq E., van Grinsven, Erinke, Udalova, Irina A., Sechi, Leonardo A.
Publicado 2020

ROS-producing immature neutrophils in giant cell arteritis are linked to vascular pathologies

por Wang, Lihui, Ai, Zhichao, Khoyratty, Tariq, Zec, Kristina, Eames, Hayley L., van Grinsven, Erinke, Hudak, Alison, Morris, Susan, Ahern, David, Monaco, Claudia, Eruslanov, Evgeniy B., Luqmani, Raashid, Udalova, Irina A.
Publicado 2020

The Zinc Finger Protein Zbtb18 Represses Expression of Class I Phosphatidylinositol 3-Kinase Subunits and Inhibits Plasma Cell Differentiation

por Xie, Bin, Khoyratty, Tariq E., Abu-Shah, Enas, F. Cespedes, Pablo, MacLean, Andrew J., Pirgova, Gabriela, Hu, Zhiyuan, Ahmed, Ahmed A., Dustin, Michael L., Udalova, Irina A., Arnon, Tal I.
Publicado 2021

IRF5:RelA Interaction Targets Inflammatory Genes in Macrophages

por Saliba, David G., Heger, Andreas, Eames, Hayley L., Oikonomopoulos, Spyros, Teixeira, Ana, Blazek, Katrina, Androulidaki, Ariadne, Wong, Daniel, Goh, Fui G., Weiss, Miriam, Byrne, Adam, Pasparakis, Manolis, Ragoussis, Jiannis, Udalova, Irina A.
Publicado 2014

Interferon Regulatory Factor 5 Controls Necrotic Core Formation in Atherosclerotic Lesions by Impairing Efferocytosis

por Seneviratne, Anusha N., Edsfeldt, Andreas, Cole, Jennifer E., Kassiteridi, Christina, Swart, Maarten, Park, Inhye, Green, Patricia, Khoyratty, Tariq, Saliba, David, Goddard, Michael E., Sansom, Stephen N., Goncalves, Isabel, Krams, Rob, Udalova, Irina A., Monaco, Claudia
Publicado 2017

Distinct transcription factor networks control neutrophil-driven inflammation

por Khoyratty, Tariq E, Ai, Zhichao, Ballesteros, Ivan, Eames, Hayley L, Mathie, Sara, Martín-Salamanca, Sandra, Wang, Lihui, Hemmings, Ashleigh, Willemsen, Nicola, von Werz, Valentin, Zehrer, Annette, Walzog, Barbara, van Grinsven, Erinke, Hidalgo, Andres, Udalova, Irina A
Publicado 2021

Plasma iron controls neutrophil production and function

por Frost, Joe N., Wideman, Sarah K., Preston, Alexandra E., Teh, Megan R., Ai, Zhichao, Wang, Lihui, Cross, Amy, White, Natasha, Yazicioglu, Yavuz, Bonadonna, Michael, Clarke, Alexander J., Armitage, Andrew E., Galy, Bruno, Udalova, Irina A., Drakesmith, Hal
Publicado 2022

Deuterated Arachidonic Acid Ameliorates Lipopolysaccharide-Induced Lung Damage in Mice

por Molchanova, Alla Y., Rjabceva, Svetlana N., Melik-Kasumov, Tigran B., Pestov, Nikolay B., Angelova, Plamena R., Shmanai, Vadim V., Sharko, Olga L., Bekish, Andrei V., James, Genevieve, Park, Hui Gyu, Udalova, Irina A., Brenna, J. Thomas, Shchepinov, Mikhail S.
Publicado 2022

Defactinib inhibits PYK2 phosphorylation of IRF5 and reduces intestinal inflammation

por Ryzhakov, Grigory, Almuttaqi, Hannah, Corbin, Alastair L., Berthold, Dorothée L., Khoyratty, Tariq, Eames, Hayley L., Bullers, Samuel, Pearson, Claire, Ai, Zhichao, Zec, Kristina, Bonham, Sarah, Fischer, Roman, Jostins-Dean, Luke, Travis, Simon P. L., Kessler, Benedikt M., Udalova, Irina A.
Publicado 2021

Endothelium-derived extracellular vesicles promote splenic monocyte mobilization in myocardial infarction

por Akbar, Naveed, Digby, Janet E., Cahill, Thomas J., Tavare, Abhijeet N., Corbin, Alastair L., Saluja, Sushant, Dawkins, Sam, Edgar, Laurienne, Rawlings, Nadiia, Ziberna, Klemen, McNeill, Eileen, Johnson, Errin, Aljabali, Alaa A., Dragovic, Rebecca A., Rohling, Mala, Belgard, T. Grant, Udalova, Irina A., Greaves, David R., Channon, Keith M., Riley, Paul R., Anthony, Daniel C., Choudhury, Robin P.
Publicado 2017

Neutrophil phenotypes and functions in cancer: A consensus statement

por Quail, Daniela F., Amulic, Borko, Aziz, Monowar, Barnes, Betsy J., Eruslanov, Evgeniy, Fridlender, Zvi G., Goodridge, Helen S., Granot, Zvi, Hidalgo, Andrés, Huttenlocher, Anna, Kaplan, Mariana J., Malanchi, Ilaria, Merghoub, Taha, Meylan, Etienne, Mittal, Vivek, Pittet, Mikael J., Rubio-Ponce, Andrea, Udalova, Irina A., van den Berg, Timo K., Wagner, Denisa D., Wang, Ping, Zychlinsky, Arturo, de Visser, Karin E., Egeblad, Mikala, Kubes, Paul
Publicado 2022