Type 2 Diabetes: Multiple Genes, Multiple Diseases

por Udler, Miriam S.
Publicado 2019

Phenotypic and genetic classification of diabetes

por Deutsch, Aaron J., Ahlqvist, Emma, Udler, Miriam S.
Publicado 2022

Defining Heterogeneity Among Women With Gestational Diabetes Mellitus

por Powe, Camille E., Hivert, Marie-France, Udler, Miriam S.
Publicado 2020

Genetic Risk Scores for Diabetes Diagnosis and Precision Medicine

por Udler, Miriam S, McCarthy, Mark I, Florez, Jose C, Mahajan, Anubha
Publicado 2019

THU640 Clustering Of Genetic Loci Identifies 4 Distinct Polycystic Ovarian Syndrome Physiologic Pathways

por Stamou, Maria, Smith, Kirk T, Kim, Hyunkyung, Balasubramanian, Ravikumar, Gray, Kathryn, Udler, Miriam
Publicado 2023

OR05-1 Genetic Discovery and Translational Decision Support from Exome Sequencing of 45,231 Type 2 Diabetes Cases and Controls from Five Ancestries

por Udler, Miriam, Flannick, Jason, Mercader, Josep, Fuchsberger, Christian, Mahajan, Anubha, Consortium, for the AMP-T2D
Publicado 2019

Geospatial Analysis of Individual and Community-Level Socioeconomic Factors Impacting SARS-CoV-2 Prevalence and Outcomes

por Cromer, Sara J., Lakhani, Chirag M., Wexler, Deborah J, Burnett-Bowie, Sherri-Ann M., Udler, Miriam, Patel, Chirag J.
Publicado 2020

Statistical evidence for high‐penetrance MODY‐causing genes in a large population‐based cohort

por Billings, Liana K., Shi, Zhuqing, Resurreccion, W. Kyle, Wang, Chi‐Hsiung, Wei, Jun, Pollin, Toni I., Udler, Miriam S., Xu, Jianfeng
Publicado 2022

Algorithmic identification of atypical diabetes in electronic health record (EHR) systems

por Cromer, Sara J., Chen, Victoria, Han, Christopher, Marshall, William, Emongo, Shekina, Greaux, Evelyn, Majarian, Tim, Florez, Jose C., Mercader, Josep, Udler, Miriam S.
Publicado 2022

Type 2 Diabetes Polygenic Score Predicts the Risk of Glucocorticoid-Induced Hyperglycemia in Patients Without Diabetes

por Deutsch, Aaron J., Schroeder, Philip H., Mandla, Ravi, Kang, Sarah, Erenler, Feyza, Mercader, Josep M., Udler, Miriam S., Florez, Jose C., Brenner, Laura N.
Publicado 2023

Algorithms for the identification of prevalent diabetes in the All of Us Research Program validated using polygenic scores – a new resource for diabetes precision medicine

por Szczerbinski, Lukasz, Mandla, Ravi, Schroeder, Philip, Porneala, Bianca C., Li, Josephine H., Florez, Jose C., Mercader, Josep M., Manning, Alisa K., Udler, Miriam S.
Publicado 2023

386 A novel truncating variant of EBF2 disrupts human adipocyte differentiation in lipodystrophy syndromes: an example of a discovery from a clinical translational pipeline

por Foss-Freitas, Maria C., Wys, Noel, Udler, Miriam, Pais, Lynne, da Rocha, Andre Monteiro, MacDougald, Ormond A., Oral, Elif A., Chun, Tae-Hwa
Publicado 2023

FRI018 A Novel Truncating Variant Of EBF2 Disrupts Human Adipocyte Differentiation In Lipodystrophy Syndromes: An Example Of A Discovery From A Clinical Translational Pipeline

por Foss de Freitas, Maria Cristina, Wys, Noel, Udler, Miriam, Pais, Lynn, da Rocha, Andre Monteiro, MacDougald, Ormond A, Oral, Elif A, Chun, Tae-Hwa
Publicado 2023

Separating the direct effects of traits on atherosclerotic cardiovascular disease from those mediated by type 2 diabetes

por Walker, Venexia M., Vujkovic, Marijana, Carter, Alice R., Davies, Neil M., Udler, Miriam S., Levin, Michael G., Davey Smith, George, Voight, Benjamin F., Gaunt, Tom R., Damrauer, Scott M.
Publicado 2022

Genetic Loci and Physiologic Pathways Involved in Gestational Diabetes Mellitus Implicated Through Clustering

por Powe, Camille E., Udler, Miriam S., Hsu, Sarah, Allard, Catherine, Kuang, Alan, Manning, Alisa K., Perron, Patrice, Bouchard, Luigi, Lowe, William L., Scholtens, Denise, Florez, Jose C., Hivert, Marie-France
Publicado 2021

Variance-quantitative trait loci enable systematic discovery of gene-environment interactions for cardiometabolic serum biomarkers

por Westerman, Kenneth E., Majarian, Timothy D., Giulianini, Franco, Jang, Dong-Keun, Miao, Jenkai, Florez, Jose C., Chen, Han, Chasman, Daniel I., Udler, Miriam S., Manning, Alisa K., Cole, Joanne B.
Publicado 2022

Report of Prolonged Neonatal Hypoglycemia in Three Infants of Mothers With Variants in HNF1A

por Cromer, Sara Jane, Sella, Aluma Chovel, Rosenberg, Emily, Scully, Kevin, McDonnell, Marie, Abreu, Ana Paula, Weil, Michelle, Bernstein, Sarah N., Quinn, Maryanne, Powe, Camille, Mitchell, Deborah M., Udler, Miriam S.
Publicado 2022

Genetic determinants of daytime napping and effects on cardiometabolic health

por Dashti, Hassan S., Daghlas, Iyas, Lane, Jacqueline M., Huang, Yunru, Udler, Miriam S., Wang, Heming, Ollila, Hanna M., Jones, Samuel E., Kim, Jaegil, Wood, Andrew R., Weedon, Michael N., Aslibekyan, Stella, Garaulet, Marta, Saxena, Richa
Publicado 2021

Type 2 diabetes genetic loci informed by multi-trait associations point to disease mechanisms and subtypes: A soft clustering analysis

por Udler, Miriam S., Kim, Jaegil, von Grotthuss, Marcin, Bonàs-Guarch, Sílvia, Cole, Joanne B., Chiou, Joshua, Boehnke, Michael, Laakso, Markku, Atzmon, Gil, Glaser, Benjamin, Mercader, Josep M., Gaulton, Kyle, Flannick, Jason, Getz, Gad, Florez, Jose C.
Publicado 2018

A Long Non-coding RNA, LOC157273, Is an Effector Transcript at the Chromosome 8p23.1-PPP1R3B Metabolic Traits and Type 2 Diabetes Risk Locus

por Manning, Alisa K., Goustin, Anton Scott, Kleinbrink, Erica L., Thepsuwan, Pattaraporn, Cai, Juan, Ju, Donghong, Leong, Aaron, Udler, Miriam S., Brown, James Bentley, Goodarzi, Mark O., Rotter, Jerome I., Sladek, Robert, Meigs, James B., Lipovich, Leonard
Publicado 2020