Intrinsic and acquired drug resistance to LSD1 inhibitors in small cell lung cancer occurs through a TEAD4‐driven transcriptional state

por Yan, Wen, Chung, Chi‐Yeh, Xie, Tao, Ozeck, Mark, Nichols, Timothy C., Frey, Jessica, Udyavar, Akshata R., Sharma, Shikhar, Paul, Thomas A.
Publicado 2021

Transcriptomic profiling of adjuvant colorectal cancer identifies three key prognostic biological processes and a disease specific role for granzyme B

por Daemen, Anneleen, Udyavar, Akshata R., Sandmann, Thomas, Li, Congfen, Bosch, Linda J. W., O’Gorman, William, Li, Yijin, Au-Yeung, Amelia, Takahashi, Chikara, Kabbarah, Omar, Bourgon, Richard, Hegde, Priti, Bais, Carlos, Das Thakur, Meghna
Publicado 2021

Co-expression network analysis identifies Spleen Tyrosine Kinase (SYK) as a candidate oncogenic driver in a subset of small-cell lung cancer

por Udyavar, Akshata R, Hoeksema, Megan D, Clark, Jonathan E, Zou, Yong, Tang, Zuojian, Li, Zhiguo, Li, Ming, Chen, Heidi, Statnikov, Alexander, Shyr, Yu, Liebler, Daniel C, Field, John, Eisenberg, Rosana, Estrada, Lourdes, Massion, Pierre P, Quaranta, Vito
Publicado 2013

Integrated digital pathology and transcriptome analysis identifies molecular mediators of T-cell exclusion in ovarian cancer

por Desbois, Mélanie, Udyavar, Akshata R., Ryner, Lisa, Kozlowski, Cleopatra, Guan, Yinghui, Dürrbaum, Milena, Lu, Shan, Fortin, Jean-Philippe, Koeppen, Hartmut, Ziai, James, Chang, Ching-Wei, Keerthivasan, Shilpa, Plante, Marie, Bourgon, Richard, Bais, Carlos, Hegde, Priti, Daemen, Anneleen, Turley, Shannon, Wang, Yulei
Publicado 2020

Targeting CD73 with AB680 (Quemliclustat), a Novel and Potent Small-Molecule CD73 Inhibitor, Restores Immune Functionality and Facilitates Antitumor Immunity

por Piovesan, Dana, Tan, Joanne B.L., Becker, Annette, Banuelos, Jesus, Narasappa, Nell, DiRenzo, Daniel, Zhang, Kristen, Chen, Ada, Ginn, Elaine, Udyavar, Akshata R., Yin, Fangfang, Paprcka, Susan L., Purandare, Bhamini, Park, Timothy W., Kimura, Nikki, Kalisiak, Jaroslaw, Young, Stephen W., Powers, Jay P., Schindler, Uli, Sivick, Kelsey E., Walters, Matthew J.
Publicado 2022