Dissecting the sub-structure of the intraflagellar transport complex B

por Texier, Y, van Reeuwijk, J, Mans, DA, Roepman, R, Boldt, K, Ueffing, M
Publicado 2012

Efficacy of PARP inhibition in Pde6a mutant mouse models for retinitis pigmentosa depends on the quality and composition of individual human mutations

por Jiao, K, Sahaboglu, A, Zrenner, E, Ueffing, M, Ekström, P A R, Paquet-Durand, F
Publicado 2016

Identification of novel interaction partners for Vlgr1b/GPR98 - a key component of the periciliary Usher syndrome protein network in photoreceptor cells

por Knapp, B, Letteboer, SJ, van Wijk, E, Boldt, K, Ueffing, M, Kremer, H, Roepman, R, Wolfrum, U
Publicado 2012

Disruption of intraflagellar protein transport in photoreceptor cilia causes Leber congenital amaurosis in humans and mice

por Boldt, K, Mans, DA, Won, J, van Reeuwijk, J, Texier, Y, Nishina, PM, Roepman, R, Ueffing, M
Publicado 2012

Pericentrin interacts with KASH domain-containing protein Syne-2

por Falk, N, Kessler, K, Glöckner, J, Boldt, K, Ueffing, M, Roepman, R, Thiel, C, Brandstätter, JH, Gießl, A
Publicado 2015

From proteomic data to networks: statistics and methods reveal ciliary protein interaction landscape

por Lu, Q, Koutroumpas, K, Boldt, K, Reeuwijk, J Van, Katsanis, N, Képès, F, Roepman, R, Ueffing, M, Russell, RB
Publicado 2015

Scrutinizing ciliopathies by unravelling the ciliary interactome

por van Reeuwijk, J, Boldt, K, Mans, DA, Texier, Y, van Beersum, SE, Letteboer, SJ, Nguyen, MTT, Ueffing, M, Roepman, R
Publicado 2012

Knockout of PARG110 confers resistance to cGMP-induced toxicity in mammalian photoreceptors

por Sahaboglu, A, Tanimoto, N, Bolz, S, Garrido, M G, Ueffing, M, Seeliger, M W, Löwenheim, H, Ekström, P, Paquet-Durand, F
Publicado 2014

Differential requirements of ciliogenic/ciliopathy module components in restricting Joubert syndrome-associated Arl13b to a C. elegans Inv-like ciliary compartment

por Blacque, O, Cevik, S, Clarke, L, Van Wijk, E, Sanders, A, Van Reeuwijk, J, Boldt, K, Ueffing, M, Roepman, R, Kremer, H
Publicado 2012

Retinitis pigmentosa: rapid neurodegeneration is governed by slow cell death mechanisms

por Sahaboglu, A, Paquet-Durand, O, Dietter, J, Dengler, K, Bernhard-Kurz, S, Ekström, P AR, Hitzmann, B, Ueffing, M, Paquet-Durand, F
Publicado 2013

A systems biology approach towards the prediction of ciliopathy mechanisms

por Koutroumpas, K, Dam, J Van, Toedt, G, Lu, Q, Reeuwijk, J Van, Boldt, K, Gibson, T, Roepman, R, Ueffing, M, Russell, RB, Huynen, M, Elati, M, Képès, F
Publicado 2015

Systematic exploration of the ciliary protein landscape by large-scale affinity proteomics

por Boldt, K, Van Reeuwijk, J, Lu, Q, Koutroumpas, K, Horn, N, Beersum, S Van, Texier, Y, Nguyen, TM, Willer, JR, Katsanis, N, Képès, F, Russell, RB, Ueffing, M, Roepman, R
Publicado 2015

PDZD7 connects the Usher protein complex to the intraflagellar transport machinery

por Vrieze, E De, Creemers, L, Sorusch, N, Gorris, M, Reeuwijk, J Van, Beersum, S Van, Knapp, B, Boldt, K, Ueffing, M, Roepman, R, Wijk, E Van, Wolfram, U, Kremer, H
Publicado 2015

The lebercilin-like protein is embedded in a ciliary protein network and is preferentially expressed in motile cilia

por Mans, DA, Coene, KLM, Boldt, K, Lamers, IJC, van Reeuwijk, J, Loges, NT, Bolat, E, Franke, L, Hetterschijt, L, Letteboer, SJF, Peters, TA, Omran, H, Cremers, FPM, Ueffing, M, Roepman, R
Publicado 2012

SYSCILIA, “A systems biology approach to dissect cilia function and its disruption in human genetic disease”

por Roepman, R, Ueffing, M, Kremer, H, Huynen, MA, Gibson, TJ, Katsanis, N, Walz, GT, Wolfrum, U, Franco, B, Giles, RH, Beales, PL, Johnson, CA, Blacque, OE, Pontoglio, M, Képès, F, Apic, G, Russell, RB, Omran, H
Publicado 2012

High fat diet-induced modifications in membrane lipid and mitochondrial-membrane protein signatures precede the development of hepatic insulin resistance in mice

por Kahle, M., Schäfer, A., Seelig, A., Schultheiß, J., Wu, M., Aichler, M., Leonhardt, J., Rathkolb, B., Rozman, J., Sarioglu, H., Hauck, S.M., Ueffing, M., Wolf, E., Kastenmueller, G., Adamski, J., Walch, A., Hrabé de Angelis, M., Neschen, S.
Publicado 2014

A high-throughput genome-wide siRNA screen for ciliogenesis identifies new ciliary functional components and ciliopathy genes

por Szymanska, K, Wheway, G, Doherty, D, Schmidts, M, Mans, D, Nguyen, TMT, Boldt, K, Tödt, G, Abdelhamed, Z, Wunderlich, K, Natarajan, S, Parry, DA, Logan, CV, Herridge, W, Sorusch, N, Wolfrum, U, Ueffing, M, Roepman, R, Mitchison, H, Johnson, C
Publicado 2015