Mechanistic Studies of Idiosyncratic DILI: Clinical Implications

por Uetrecht, Jack
Publicado 2019

Idiosyncratic Drug Reactions: A 35-Year Chemical Research in Toxicology Perspective

por Uetrecht, Jack
Publicado 2022

Immune mechanisms of idiosyncratic drug-induced liver injury

por Mak, Alastair, Uetrecht, Jack
Publicado 2017

Mechanism of idiosyncratic drug induced liver injury (DILI): unresolved basic issues

por Teschke, Rolf, Uetrecht, Jack
Publicado 2021

Direct Oxidation and Covalent Binding of Isoniazid to Rodent Liver and Human Hepatic Microsomes: Humans Are More Like Mice than Rats

por Metushi, Imir G., Nakagawa, Tetsuya, Uetrecht, Jack
Publicado 2012

Testing Possible Risk Factors for Idiosyncratic Drug-Induced Liver Injury Using an Amodiaquine Mouse Model and Co-treatment with 1-Methyl-d-Tryptophan or Acetaminophen

por Cho, Tiffany, Kok, Lie Yun, Uetrecht, Jack
Publicado 2021

Idiosyncratic Drug-Induced Liver Injury: Mechanistic and Clinical Challenges

por Jee, Alison, Sernoskie, Samantha Christine, Uetrecht, Jack
Publicado 2021

The Role of Myeloperoxidase in Clozapine-Induced Inflammation: A Mechanistic Update for Idiosyncratic Drug-Induced Agranulocytosis

por Sernoskie, Samantha Christine, Jee, Alison, Uetrecht, Jack
Publicado 2023

Investigating the Mechanism of Trimethoprim-Induced Skin Rash and Liver Injury

por Cao, Yanshan, Bairam, Ahsan, Jee, Alison, Liu, Ming, Uetrecht, Jack
Publicado 2021

Bioactivation of Nevirapine to a Reactive Quinone Methide: Implications for Liver Injury

por Sharma, Amy M., Li, Yan, Novalen, Maria, Hayes, M. Anthony, Uetrecht, Jack
Publicado 2012

Real-time imaging of oxidative and nitrosative stress in the liver of live animals for drug-toxicity testing

por Shuhendler, Adam J., Pu, Kanyi, Cui, Lina, Uetrecht, Jack P., Rao, Jianghong
Publicado 2014

Deferiprone‐induced agranulocytosis: 20 years of clinical observations

por Tricta, Fernando, Uetrecht, Jack, Galanello, Renzo, Connelly, John, Rozova, Anna, Spino, Michael, Palmblad, Jan
Publicado 2016

Clozapine Induces an Acute Proinflammatory Response That Is Attenuated by Inhibition of Inflammasome Signaling: Implications for Idiosyncratic Drug-Induced Agranulocytosis

por Sernoskie, Samantha Christine, Lobach, Alexandra R, Kato, Ryuji, Jee, Alison, Weston, Joseph Kyle, Uetrecht, Jack
Publicado 2021