Dynamic Allostery Modulates Catalytic Activity by Modifying the Hydrogen Bonding Network in the Catalytic Site of Human Pin1

por Wang, Jing, Kawasaki, Ryosuke, Uewaki, Jun-ichi, Rashid, Arif U. R., Tochio, Naoya, Tate, Shin-ichi
Publicado 2017

Non-RVD mutations that enhance the dynamics of the TAL repeat array along the superhelical axis improve TALEN genome editing efficacy

por Tochio, Naoya, Umehara, Kohei, Uewaki, Jun-ichi, Flechsig, Holger, Kondo, Masaharu, Dewa, Takehisa, Sakuma, Tetsushi, Yamamoto, Takashi, Saitoh, Takashi, Togashi, Yuichi, Tate, Shin-ichi
Publicado 2016