Mechanistic target of rapamycin signaling in human nervous system development and disease

por Girodengo, Marie, Ultanir, Sila K., Bateman, Joseph M.
Publicado 2022

Control of synaptic vesicle release probability via VAMP4 targeting to endolysosomes

por Ivanova, Daniela, Dobson, Katharine L., Gajbhiye, Akshada, Davenport, Elizabeth C., Hacker, Daniela, Ultanir, Sila K., Trost, Matthias, Cousin, Michael A.
Publicado 2021

Phosphorylation of the novel mTOR substrate Unkempt regulates cellular morphogenesis

por Baskaran, Pranetha, Mihaylov, Simeon R., Vinsland, Elin, Shah, Kriti, Granat, Lucy, Ultanir, Sila K., Tee, Andrew R., Murn, Jernej, Bateman, Joseph M.
Publicado 2022

MST3 Kinase Phosphorylates TAO1/2 to Enable Myosin Va Function in Promoting Spine Synapse Development

por Ultanir, Sila K., Yadav, Smita, Hertz, Nicholas T., Oses-Prieto, Juan A., Claxton, Suzanne, Burlingame, Alma L., Shokat, Kevan M., Jan, Lily Y., Jan, Yuh-Nung
Publicado 2014

Chemical genetic identification of GAK substrates reveals its role in regulating Na(+)/K(+)-ATPase

por Lin, Amy W, Gill, Kalbinder K, Castañeda, Marisol Sampedro, Matucci, Irene, Eder, Noreen, Claxton, Suzanne, Flynn, Helen, Snijders, Ambrosius P, George, Roger, Ultanir, Sila K
Publicado 2018

Chemical genetic identification of CDKL5 substrates reveals its role in neuronal microtubule dynamics

por Baltussen, Lucas L, Negraes, Priscilla D, Silvestre, Margaux, Claxton, Suzanne, Moeskops, Max, Christodoulou, Evangelos, Flynn, Helen R, Snijders, Ambrosius P, Muotri, Alysson R, Ultanir, Sila K
Publicado 2018

Loss of NDR1/2 kinases impairs endomembrane trafficking and autophagy leading to neurodegeneration

por Roşianu, Flavia, Mihaylov, Simeon R, Eder, Noreen, Martiniuc, Antonie, Claxton, Suzanne, Flynn, Helen R, Jalal, Shamsinar, Domart, Marie-Charlotte, Collinson, Lucy, Skehel, Mark, Snijders, Ambrosius P, Krause, Matthias, Tooze, Sharon A, Ultanir, Sila K
Publicado 2022

YAP1/TAZ drives ependymoma-like tumour formation in mice

por Eder, Noreen, Roncaroli, Federico, Dolmart, Marie-Charlotte, Horswell, Stuart, Andreiuolo, Felipe, Flynn, Helen R., Lopes, Andre T., Claxton, Suzanne, Kilday, John-Paul, Collinson, Lucy, Mao, Jun-Hao, Pietsch, Torsten, Thompson, Barry, Snijders, Ambrosius P., Ultanir, Sila K.
Publicado 2020

Author Correction: YAP1/TAZ drives ependymoma-like tumour formation in mice

por Eder, Noreen, Roncaroli, Federico, Domart, Marie-Charlotte, Horswell, Stuart, Andreiuolo, Felipe, Flynn, Helen R., Lopes, Andre T., Claxton, Suzanne, Kilday, John-Paul, Collinson, Lucy, Mao, Jun-Hao, Pietsch, Torsten, Thompson, Barry, Snijders, Ambrosius P., Ultanir, Sila K.
Publicado 2020

Discovery of a Potent and Selective CDKL5/GSK3 Chemical Probe That Is Neuroprotective

por Ong, Han Wee, Liang, Yi, Richardson, William, Lowry, Emily R., Wells, Carrow I., Chen, Xiangrong, Silvestre, Margaux, Dempster, Kelvin, Silvaroli, Josie A., Smith, Jeffery L., Wichterle, Hynek, Pabla, Navjot S., Ultanir, Sila K., Bullock, Alex N., Drewry, David H., Axtman, Alison D.
Publicado 2023

The master energy homeostasis regulator PGC-1α exhibits an mRNA nuclear export function

por Mihaylov, Simeon R., Castelli, Lydia M., Lin, Ya-Hui, Gül, Aytac, Soni, Nikita, Hastings, Christopher, Flynn, Helen R., Păun, Oana, Dickman, Mark J., Snijders, Ambrosius P., Goldstone, Robert, Bandmann, Oliver, Shelkovnikova, Tatyana A., Mortiboys, Heather, Ultanir, Sila K., Hautbergue, Guillaume M.
Publicado 2023

A Potent and Selective CDKL5/GSK3 Chemical Probe is Neuroprotective

por Ong, Han Wee, Liang, Yi, Richardson, William, Lowry, Emily R., Wells, Carrow I., Chen, Xiangrong, Silvestre, Margaux, Dempster, Kelvin, Silvaroli, Josie A., Smith, Jeffery L., Wichterle, Hynek, Pabla, Navjot S., Ultanir, Sila K., Bullock, Alex N., Drewry, David H., Axtman, Alison D.
Publicado 2023

Discovery and characterization of a specific inhibitor of serine-threonine kinase cyclin-dependent kinase-like 5 (CDKL5) demonstrates role in hippocampal CA1 physiology

por Castano, Anna, Silvestre, Margaux, Wells, Carrow I, Sanderson, Jennifer L, Ferrer, Carla A, Ong, Han Wee, Lang, Yi, Richardson, William, Silvaroli, Josie A, Bashore, Frances M, Smith, Jeffery L, Genereux, Isabelle M, Dempster, Kelvin, Drewry, David H, Pabla, Navlot S, Bullock, Alex N, Benke, Tim A, Ultanir, Sila K, Axtman, Alison D
Publicado 2023