Cdk1 Phosphorylation of the Dam1 Complex Strengthens Kinetochore-Microtubule Attachments

por Gutierrez, Abraham, Kim, Jae ook, Umbreit, Neil T., Asbury, Charles L., Davis, Trisha N., Miller, Matthew P., Biggins, Sue
Publicado 2020

Cooperation of the Dam1 and Ndc80 kinetochore complexes enhances microtubule coupling and is regulated by aurora B

por Tien, Jerry F., Umbreit, Neil T., Gestaut, Daniel R., Franck, Andrew D., Cooper, Jeremy, Wordeman, Linda, Gonen, Tamir, Asbury, Charles L., Davis, Trisha N.
Publicado 2010

The Ndc80 complex bridges two Dam1 complex rings

por Kim, Jae ook, Zelter, Alex, Umbreit, Neil T, Bollozos, Athena, Riffle, Michael, Johnson, Richard, MacCoss, Michael J, Asbury, Charles L, Davis, Trisha N
Publicado 2017

Human nuclear RNAi-defective 2 (NRDE2) is an essential RNA splicing factor

por Jiao, Alan L., Perales, Roberto, Umbreit, Neil T., Haswell, Jeffrey R., Piper, Mary E., Adams, Brian D., Pellman, David, Kennedy, Scott, Slack, Frank J.
Publicado 2019

Kinetochores require oligomerization of Dam1 complex to maintain microtubule attachments against tension and promote biorientation

por Umbreit, Neil T., Miller, Matthew P., Tien, Jerry F., Cattin-Ortolá, Jérôme, Gui, Long, Lee, Kelly K., Biggins, Sue, Asbury, Charles L., Davis, Trisha N.
Publicado 2014

The molecular architecture of the Dam1 kinetochore complex is defined by cross-linking based structural modelling

por Zelter, Alex, Bonomi, Massimiliano, Kim, Jae ook, Umbreit, Neil T., Hoopmann, Michael R., Johnson, Richard, Riffle, Michael, Jaschob, Daniel, MacCoss, Michael J., Moritz, Robert L., Davis, Trisha N.
Publicado 2015

MECHANISMS GENERATING CANCER GENOME COMPLEXITY FROM A SINGLE CELL DIVISION ERROR

por Umbreit, Neil T., Zhang, Cheng-Zhong, Lynch, Luke D., Blaine, Logan J., Cheng, Anna M., Tourdot, Richard, Sun, Lili, Almubarak, Hannah F., Judge, Kim, Mitchell, Thomas J., Spektor, Alexander, Pellman, David
Publicado 2020

VTT-006, an anti-mitotic compound, binds to the Ndc80 complex and suppresses cancer cell growth in vitro

por Laine, Leena J., Mäki-Jouppila, Jenni H.E., Kutvonen, Emma, Tiikkainen, Pekka, Nyholm, Thomas K.M., Tien, Jerry F., Umbreit, Neil T., Härmä, Ville, Kallio, Lila, Davis, Trisha N., Asbury, Charles L., Poso, Antti, Gorbsky, Gary J., Kallio, Marko J.
Publicado 2021

The molecular architecture of the yeast spindle pole body core determined by Bayesian integrative modeling

por Viswanath, Shruthi, Bonomi, Massimiliano, Kim, Seung Joong, Klenchin, Vadim A., Taylor, Keenan C., Yabut, King C., Umbreit, Neil T., Van Epps, Heather A., Meehl, Janet, Jones, Michele H., Russel, Daniel, Velazquez-Muriel, Javier A., Winey, Mark, Rayment, Ivan, Davis, Trisha N., Sali, Andrej, Muller, Eric G.
Publicado 2017

The nucleosome acidic patch and H2A ubiquitination underlie mSWI/SNF recruitment in synovial sarcoma

por McBride, Matthew J., Mashtalir, Nazar, Winter, Evan B., Dao, Hai T., Filipovski, Martin, D’Avino, Andrew R., Seo, Hyuk-Soo, Umbreit, Neil T., St. Pierre, Roodolph, Valencia, Alfredo M., Qian, Kristin, Zullow, Hayley J., Jaffe, Jacob D., Dhe-Paganon, Sirano, Muir, Tom W., Kadoch, Cigall
Publicado 2020

Author Correction: The nucleosome acidic patch and H2A ubiquitination underlie mSWI/SNF recruitment in synovial sarcoma

por McBride, Matthew J., Mashtalir, Nazar, Winter, Evan B., Dao, Hai T., Filipovski, Martin, D’Avino, Andrew R., Seo, Hyuk-Soo, Umbreit, Neil T., St. Pierre, Roodolph, Valencia, Alfredo M., Qian, Kristin, Zullow, Hayley J., Jaffe, Jacob D., Dhe-Paganon, Sirano, Muir, Tom W., Kadoch, Cigall
Publicado 2020