Pharmacoresistant seizures and IDH mutation in low-grade gliomas

por Correia, Carlos Eduardo, Umemura, Yoshie, Flynn, Jessica R, Reiner, Anne S, Avila, Edward K
Publicado 2021

DDRE-19. PHASE 0/I TRIAL OF MYCOPHENOLATE MOFETIL COMBINED WITH RADIATION TO OVERCOME GLIOBLASTOMA TREATMENT RESISTANCE BY TARGETING DE-NOVO PURINE METABOLISM

por Umemura, Yoshie, Sun, Yilun, Junck, Larry, Leung, Denise, Kim, Michelle, Al-Holou, Wajd, Sagher, Oren, Heth, Jason, Lyssiotis, Costas, Marini, Bernard, Lawrence, Theodore, Wahl, Daniel
Publicado 2021

Uncovering Spatiotemporal Heterogeneity of High-Grade Gliomas: From Disease Biology to Therapeutic Implications

por Comba, Andrea, Faisal, Syed M., Varela, Maria Luisa, Hollon, Todd, Al-Holou, Wajd N., Umemura, Yoshie, Nunez, Felipe J., Motsch, Sebastien, Castro, Maria G., Lowenstein, Pedro R.
Publicado 2021

NEIM-08 A PHASE II STUDY OF MULTIPARAMETRIC MR-GUIDED HIGH DOSE ADAPTIVE RADIOTHERAPY WITH CONCURRENT TEMOZOLOMIDE IN PATIENTS WITH NEWLY DIAGNOSED GLIOBLASTOMA

por Kim, Michelle, Aryal, Madhava, Rosen, Benjamin, Parmar, Hemant, You, Daekeun, Junck, Larry, Leung, Denise, Umemura, Yoshie, Heth, Jason, Al-Holou, Wajd, Hollon, Todd, Wahl, Daniel, Lawrence, Theodore, Cao, Yue
Publicado 2022

DDRE-28. MECHANISTIC AND THERAPEUTIC LINKS BETWEEN PURINE BIOSYNTHESIS AND DNA DAMAGE IN GLIOBLASTOMA

por Scott, Andrew, Zhou, Weihua, Wilder-Romans, Kari, Feng, Jiane, Wu, Zhe, Andren, Anthony, Zhang, Li, Sajjakulnukit, Peter, Kachman, Maureen, Umemura, Yoshie, Schmitt, Melanie, Qi, Nathan, Lawrence, Theodore, Lyssiotis, Costas, Wahl, Daniel
Publicado 2021

LMD-09. Outcomes and symptom benefit from palliative radiotherapy for leptomeningeal disease in breast cancer patients

por Takayesu, Jamie, Sapir, Eli, Xie, Jiaheng, Sun, Yilun, Morikawa, Aki, Junck, Larry, Leung, Denise, Umemura, Yoshie, Heth, Jason, Al-Holou, Wajd, Wahl, Daniel, Lawrence, Theodore, Mayo, Charles, Hayman, James, Kim, Michelle
Publicado 2021

DDRE-24. TARGETING PURINE METABOLISM TO OVERCOME GLIOBLASTOMA THERAPY RESISTANCE

por Zhou, Weihua, Yao, Yangyang, Scott, Andrew, Wilder-Romans, Kari, Dresser, Joseph, Werner, Christian, Sun, Hanshi, Pratt, Drew, Sajjakulnukit, Peter, Zaho, Shuang, Davis, Mary, Nelson, Barbara, Halbrook, Christopher, Zhang, Li, Gatto, Francesco, Srinivasan, Sudharsan, Jairath, Neil, Correa, Luis, Umemura, Yoshie, Walker, Angela, Kachman, Maureen, Qi, Nathan, Sarkaria, Jann, Xiong, Jianping, Morgan, Meredith, Rehemtulla, Alnawaz, Castro, Maria, Lowenstein, Pedro, Chandrasekaran, Sriram, Lawrence, Theodore, Lyssiotis, Costas, Wahl, Daniel
Publicado 2021

Purine metabolism regulates DNA repair and therapy resistance in glioblastoma

por Zhou, Weihua, Yao, Yangyang, Scott, Andrew J., Wilder-Romans, Kari, Dresser, Joseph J., Werner, Christian K., Sun, Hanshi, Pratt, Drew, Sajjakulnukit, Peter, Zhao, Shuang G., Davis, Mary, Nelson, Barbara S., Halbrook, Christopher J., Zhang, Li, Gatto, Francesco, Umemura, Yoshie, Walker, Angela K., Kachman, Maureen, Sarkaria, Jann N., Xiong, Jianping, Morgan, Meredith A., Rehemtualla, Alnawaz, Castro, Maria G., Lowenstein, Pedro, Chandrasekaran, Sriram, Lawrence, Theodore S., Lyssiotis, Costas A., Wahl, Daniel R.
Publicado 2020

HGG-18. CLINICAL EFFICACY OF ONC201 IN THALAMIC H3 K27M-MUTANT GLIOMA

por Kawakibi, Abed Rahman, Tarapore, Rohinton S, Gardner, Sharon, Chi, Andrew, Kurz, Sylvia, Wen, Patrick Y, Arrillaga-Romany, Isabel, Batchelor, Tracy T, Butowski, Nicholas A, Sumrall, Ashley, Shonka, Nicole, Harrison, Rebecca, DeGroot, John, Mehta, Minesh, Odia, Yazmin, Hall, Matthew D, Daghistani, Doured, Cloughesy, Timothy F, Ellingson, Benjamin M, Umemura, Yoshie, Schwartz, Jonathan, Yadav, Vivekanand, Cartaxo, Rodrigo, Siada, Ruby, Miklja, Zachary, Bruzek, Amy, Cantor, Evan, Wierzbicki, Kyle, Paul, Alyssa, Wolfe, Ian, Leaoard, Marcia, Garton, Hugh, Mody, Rajen, Robertson, Patricia L, Lu, Guangrong, Merdinger, Krystal, Venneti, Sriram, Oster, Wolfgang, Allen, Joshua E, Koschmann, Carl
Publicado 2020

Clinical Efficacy of ONC201 in H3K27M-Mutant Diffuse Midline Gliomas Is Driven by Disruption of Integrated Metabolic and Epigenetic Pathways

por Venneti, Sriram, Kawakibi, Abed Rahman, Ji, Sunjong, Waszak, Sebastian M., Sweha, Stefan R., Mota, Mateus, Pun, Matthew, Deogharkar, Akash, Chung, Chan, Tarapore, Rohinton S., Ramage, Samuel, Chi, Andrew, Wen, Patrick Y., Arrillaga-Romany, Isabel, Batchelor, Tracy T., Butowski, Nicholas A., Sumrall, Ashley, Shonka, Nicole, Harrison, Rebecca A., de Groot, John, Mehta, Minesh, Hall, Matthew D., Daghistani, Doured, Cloughesy, Timothy F., Ellingson, Benjamin M., Beccaria, Kevin, Varlet, Pascale, Kim, Michelle M., Umemura, Yoshie, Garton, Hugh, Franson, Andrea, Schwartz, Jonathan, Jain, Rajan, Kachman, Maureen, Baum, Heidi, Burant, Charles F., Mottl, Sophie L., Cartaxo, Rodrigo T., John, Vishal, Messinger, Dana, Qin, Tingting, Peterson, Erik, Sajjakulnukit, Peter, Ravi, Karthik, Waugh, Alyssa, Walling, Dustin, Ding, Yujie, Xia, Ziyun, Schwendeman, Anna, Hawes, Debra, Yang, Fusheng, Judkins, Alexander R., Wahl, Daniel, Lyssiotis, Costas A., de la Nava, Daniel, Alonso, Marta M., Eze, Augustine, Spitzer, Jasper, Schmidt, Susanne V., Duchatel, Ryan J., Dun, Matthew D., Cain, Jason E., Jiang, Li, Stopka, Sylwia A., Baquer, Gerard, Regan, Michael S., Filbin, Mariella G., Agar, Nathalie Y.R., Zhao, Lili, Kumar-Sinha, Chandan, Mody, Rajen, Chinnaiyan, Arul, Kurokawa, Ryo, Pratt, Drew, Yadav, Viveka N., Grill, Jacques, Kline, Cassie, Mueller, Sabine, Resnick, Adam, Nazarian, Javad, Allen, Joshua E., Odia, Yazmin, Gardner, Sharon L., Koschmann, Carl
Publicado 2023