The Neglected Liaison: Targeting Cancer Cell Metabolic Reprogramming Modifies the Composition of Non-Malignant Populations of the Tumor Microenvironment

por Iorio, Maria, Umesh Ganesh, Nikkitha, De Luise, Monica, Porcelli, Anna Maria, Gasparre, Giuseppe, Kurelac, Ivana
Publicado 2021

Repurposing the serotonin agonist Tegaserod as an anticancer agent in melanoma: molecular mechanisms and clinical implications

por Liu, Wei, Stachura, Paweł, Xu, Haifeng C., Umesh Ganesh, Nikkitha, Cox, Fiona, Wang, Ruifeng, Lang, Karl S., Gopalakrishnan, Jay, Häussinger, Dieter, Homey, Bernhard, Lang, Philipp A., Pandyra, Aleksandra A.
Publicado 2020

NDUFS3 depletion permits complex I maturation and reveals TMEM126A/OPA7 as an assembly factor binding the ND4-module intermediate

por D’Angelo, Luigi, Astro, Elisa, De Luise, Monica, Kurelac, Ivana, Umesh-Ganesh, Nikkitha, Ding, Shujing, Fearnley, Ian M., Gasparre, Giuseppe, Zeviani, Massimo, Porcelli, Anna Maria, Fernandez-Vizarra, Erika, Iommarini, Luisa
Publicado 2021

Ref-1 redox activity alters cancer cell metabolism in pancreatic cancer: exploiting this novel finding as a potential target

por Gampala, Silpa, Shah, Fenil, Lu, Xiaoyu, Moon, Hye-ran, Babb, Olivia, Umesh Ganesh, Nikkitha, Sandusky, George, Hulsey, Emily, Armstrong, Lee, Mosely, Amber L., Han, Bumsoo, Ivan, Mircea, Yeh, Jing-Ruey Joanna, Kelley, Mark R., Zhang, Chi, Fishel, Melissa L.
Publicado 2021

Inducing cancer indolence by targeting mitochondrial Complex I is potentiated by blocking macrophage-mediated adaptive responses

por Kurelac, Ivana, Iommarini, Luisa, Vatrinet, Renaud, Amato, Laura Benedetta, De Luise, Monica, Leone, Giulia, Girolimetti, Giulia, Umesh Ganesh, Nikkitha, Bridgeman, Victoria Louise, Ombrato, Luigi, Columbaro, Marta, Ragazzi, Moira, Gibellini, Lara, Sollazzo, Manuela, Feichtinger, Rene Gunther, Vidali, Silvia, Baldassarre, Maurizio, Foriel, Sarah, Vidone, Michele, Cossarizza, Andrea, Grifoni, Daniela, Kofler, Barbara, Malanchi, Ilaria, Porcelli, Anna Maria, Gasparre, Giuseppe
Publicado 2019