Recent developments in anticancer kinase inhibitors based on the pyrazolo[3,4-d]pyrimidine scaffold

por Baillache, Daniel J., Unciti-Broceta, Asier
Publicado 2020

Targeted Molecular Construct for Bioorthogonal Theranostics of PD-L1-Expressing Cancer Cells

por Chow, Shiao Y., Unciti-Broceta, Asier
Publicado 2022

Palladium-Mediated Dealkylation of N-Propargyl-Floxuridine as a Bioorthogonal Oxygen-Independent Prodrug Strategy

por Weiss, Jason T., Carragher, Neil O., Unciti-Broceta, Asier
Publicado 2015

Pyrazolopyrimide library screening in glioma cells discovers highly potent antiproliferative leads that target the PI3K/mTOR pathway

por Valero, Teresa, Baillache, Daniel J., Fraser, Craig, Myers, Samuel H., Unciti-Broceta, Asier
Publicado 2020

A Yeast Chemical Genetic Screen Identifies Inhibitors of Human Telomerase

por Wong, Lai Hong, Unciti-Broceta, Asier, Spitzer, Michaela, White, Rachel, Tyers, Mike, Harrington, Lea
Publicado 2013

Development of Potent Inhibitors of Receptor Tyrosine Kinases by Ligand-Based Drug Design and Target-Biased Phenotypic Screening

por Myers, Samuel H., Temps, Carolin, Houston, Douglas R., Brunton, Valerie G., Unciti-Broceta, Asier
Publicado 2018

Synthesis and Characterization of a Click-Assembled 18-Atom Macrocycle That Displays Selective AXL Kinase Inhibitory Activity

por Cruz-López, Olga, Temps, Carolin, Longo, Beatrice, Myers, Samuel H., Franco-Montalban, Francisco, Unciti-Broceta, Asier
Publicado 2019

Truly‐Biocompatible Gold Catalysis Enables Vivo‐Orthogonal Intra‐CNS Release of Anxiolytics

por Ortega‐Liebana, M. Carmen, Porter, Nicola J., Adam, Catherine, Valero, Teresa, Hamilton, Lloyd, Sieger, Dirk, Becker, Catherina G., Unciti‐Broceta, Asier
Publicado 2021

Bioorthogonal Uncaging of the Active Metabolite of Irinotecan by Palladium‐Functionalized Microdevices

por Adam, Catherine, Pérez‐López, Ana M., Hamilton, Lloyd, Rubio‐Ruiz, Belén, Bray, Thomas L., Sieger, Dirk, Brennan, Paul M., Unciti‐Broceta, Asier
Publicado 2018

Cancer-derived exosomes loaded with ultrathin palladium nanosheets for targeted bioorthogonal catalysis

por Sancho-Albero, María, Rubio-Ruiz, Belén, Pérez-López, Ana M., Sebastián, Víctor, Martín-Duque, Pilar, Arruebo, Manuel, Santamaría, Jesús, Unciti-Broceta, Asier
Publicado 2019

Development and Bioorthogonal Activation of Palladium-Labile Prodrugs of Gemcitabine

por Weiss, Jason T., Dawson, John C., Fraser, Craig, Rybski, Witold, Torres-Sánchez, Carmen, Bradley, Mark, Patton, E. Elizabeth, Carragher, Neil O., Unciti-Broceta, Asier
Publicado 2014

Bioorthogonal Uncaging of Cytotoxic Paclitaxel through Pd Nanosheet–Hydrogel Frameworks

por Pérez-López, Ana M., Rubio-Ruiz, Belén, Valero, Teresa, Contreras-Montoya, Rafael, Álvarez de Cienfuegos, Luis, Sebastián, Víctor, Santamaría, Jesús, Unciti-Broceta, Asier
Publicado 2020

Extracellular palladium-catalysed dealkylation of 5-fluoro-1-propargyl-uracil as a bioorthogonally activated prodrug approach

por Weiss, Jason T., Dawson, John C., Macleod, Kenneth G., Rybski, Witold, Fraser, Craig, Torres-Sánchez, Carmen, Patton, E. Elizabeth, Bradley, Mark, Carragher, Neil O., Unciti-Broceta, Asier
Publicado 2014

High-Precision Photothermal Ablation Using Biocompatible Palladium Nanoparticles and Laser Scanning Microscopy

por Rubio-Ruiz, Belén, Pérez-López, Ana M., Bray, Thomas L., Lee, Martin, Serrels, Alan, Prieto, Martín, Arruebo, Manuel, Carragher, Neil O., Sebastián, Víctor, Unciti-Broceta, Asier
Publicado 2018

N-alkynyl derivatives of 5-fluorouracil: susceptibility to palladium-mediated dealkylation and toxigenicity in cancer cell culture

por Weiss, Jason T., Fraser, Craig, Rubio-Ruiz, Belén, Myers, Samuel H., Crispin, Richard, Dawson, John C., Brunton, Valerie G., Patton, E. Elizabeth, Carragher, Neil O., Unciti-Broceta, Asier
Publicado 2014

Bright insights into palladium-triggered local chemotherapy

por Bray, Thomas L., Salji, Mark, Brombin, Alessandro, Pérez-López, Ana M., Rubio-Ruiz, Belén, Galbraith, Laura C. A., Patton, E. Elizabeth, Leung, Hing Y., Unciti-Broceta, Asier
Publicado 2018

In Cellulo Bioorthogonal Catalysis by Encapsulated AuPd Nanoalloys: Overcoming Intracellular Deactivation

por Rubio-Ruiz, Belén, Pérez-López, Ana M., Uson, Laura, Ortega-Liebana, M. Carmen, Valero, Teresa, Arruebo, Manuel, Hueso, Jose L., Sebastian, Victor, Santamaria, Jesus, Unciti-Broceta, Asier
Publicado 2023

Metallofluorescent Nanoparticles for Multimodal Applications

por Delgado-Gonzalez, Antonio, Garcia-Fernandez, Emilio, Valero, Teresa, Cano-Cortes, M. Victoria, Ruedas-Rama, Maria J., Unciti-Broceta, Asier, Sanchez-Martin, Rosario M., Diaz-Mochon, Juan J., Orte, Angel
Publicado 2018

Amide-controlled, one-pot synthesis of tri-substituted purines generates structural diversity and analogues with trypanocidal activity

por Pineda de las Infantas y Villatoro, Maria J., Unciti-Broceta, Juan D., Contreras-Montoya, Rafael, Garcia-Salcedo, Jose A., Gallo Mezo, Miguel A., Unciti-Broceta, Asier, Diaz-Mochon, Juan J.
Publicado 2015

Discovery of senolytics using machine learning

por Smer-Barreto, Vanessa, Quintanilla, Andrea, Elliott, Richard J. R., Dawson, John C., Sun, Jiugeng, Campa, Víctor M., Lorente-Macías, Álvaro, Unciti-Broceta, Asier, Carragher, Neil O., Acosta, Juan Carlos, Oyarzún, Diego A.
Publicado 2023