The Current Treatment Paradigm for Pancreatic Ductal Adenocarcinoma and Barriers to Therapeutic Efficacy

por Principe, Daniel R., Underwood, Patrick W., Korc, Murray, Trevino, Jose G., Munshi, Hidayatullah G., Rana, Ajay
Publicado 2021

Changing Practice Patterns and Improving Survival for Patients with Pancreatic Ductal Adenocarcinoma

por Underwood, Patrick W., Herremans, Kelly M., Neal, Dan, Riner, Andrea N., Nassour, Ibrahim, Hughes, Steven J., Trevino, Jose G.
Publicado 2023

Enhancing efficacy of gemcitabine in pancreatic patient-derived xenograft mouse models

por Inkoom, Andriana, Ndemazie, Nkafu, Affram, Kevin, Smith, Taylor, Zhu, Xue, Underwood, Patrick, Krishnan, Sunil, Ofori, Edward, Han, Bo, Trevino, Jose, Agyare, Edward
Publicado 2020

Loss of SMAD4 Is Associated With Poor Tumor Immunogenicity and Reduced PD-L1 Expression in Pancreatic Cancer

por Principe, Daniel R., Underwood, Patrick W., Kumar, Sandeep, Timbers, Kaytlin E., Koch, Regina M., Trevino, Jose G., Munshi, Hidayatullah G., Rana, Ajay
Publicado 2022

Osteopenia is associated with wasting in pancreatic adenocarcinoma and predicts survival after surgery

por Cameron, Miles E., Underwood, Patrick W., Williams, Iverson E., George, Thomas J., Judge, Sarah M., Yarrow, Joshua F., Trevino, Jose G., Judge, Andrew R.
Publicado 2021

Preclinical Models of Pancreatic Ductal Adenocarcinoma and Their Utility in Immunotherapy Studies

por Pham, Thao N. D., Shields, Mario A., Spaulding, Christina, Principe, Daniel R., Li, Bo, Underwood, Patrick W., Trevino, Jose G., Bentrem, David J., Munshi, Hidayatullah G.
Publicado 2021

Disparities in Pancreatic Ductal Adenocarcinoma—The Significance of Hispanic Ethnicity, Subgroup Analysis, and Treatment Facility on Clinical Outcomes

por Riner, Andrea N., Underwood, Patrick W., Yang, Kai, Herremans, Kelly M., Cameron, Miles E., Chamala, Srikar, Qiu, Peihua, George, Thomas J., Permuth, Jennifer B., Merchant, Nipun B., Trevino, Jose G.
Publicado 2020

Calcium channel blockers potentiate gemcitabine chemotherapy  in pancreatic cancer

por Principe, Daniel R., Aissa, Alexandre F., Kumar, Sandeep, Pham, Thao N. D., Underwood, Patrick W., Nair, Rakesh, Ke, Rong, Rana, Basabi, Trevino, Jose G., Munshi, Hidayatullah G., Benevolenskaya, Elizaveta V., Rana, Ajay
Publicado 2022

Transcriptomic analysis of pancreatic adenocarcinoma specimens obtained from Black and White patients

por Biel, Thomas G., Petrovskaya, Svetlana, Mascia, Francesca, Ju, Tongzhong, Fashoyin-Aje, Lola, Herremans, Kelly M., Riner, Andrea N., Underwood, Patrick W., Gerber, Michael H., Donoghue, Martha, Trevino, Jose G., Rao, V. Ashutosh
Publicado 2023

Nicotine Induces IL-8 Secretion from Pancreatic Cancer Stroma and Worsens Cancer-Induced Cachexia

por Underwood, Patrick W., Zhang, Dong Yu, Cameron, Miles E., Gerber, Michael H., Delitto, Daniel, Maduka, Michael U., Cooper, Kyle J., Han, Song, Hughes, Steven J., Judge, Sarah M., Judge, Andrew R., Trevino, Jose G.
Publicado 2020

Surgical resident experience with common bile duct exploration and assessment of performance and autonomy with formative feedback

por Nyren, Molly Q., Filiberto, Amanda C., Underwood, Patrick W., Abbott, Kenneth L., Balch, Jeremy A., Mas, Francesca Dal, Cobianchi, Lorenzo, Efron, Philip A., George, Brian C., Shickel, Benjamin, Upchurch, Gilbert R., Sarosi, George A., Loftus, Tyler J.
Publicado 2023

The interleukin-1 axis and the tumor immune microenvironment in pancreatic ductal adenocarcinoma

por Herremans, Kelly M., Szymkiewicz, Dominique D., Riner, Andrea N., Bohan, Riley P., Tushoski, Gerik W., Davidson, Aaron M., Lou, XiangYang, Leong, Man Chong, Dean, Bayli DiVita, Gerber, Michael, Underwood, Patrick W., Han, Song, Hughes, Steven J.
Publicado 2022

Local and Systemic Cytokine Profiling for Pancreatic Ductal Adenocarcinoma to Study Cancer Cachexia in an Era of Precision Medicine

por Gerber, Michael H., Underwood, Patrick W., Judge, Sarah M., Delitto, Daniel, Delitto, Andrea E., Nosacka, Rachel L., DiVita, Bayli B., Thomas, Ryan M., Permuth, Jennifer B., Hughes, Steven J., Wallet, Shannon M., Judge, Andrew R., Trevino, Jose G.
Publicado 2018

Overcoming Gemcitabine Resistance in Pancreatic Cancer Using the BCL-X(L)–Specific Degrader DT2216

por Thummuri, Dinesh, Khan, Sajid, Underwood, Patrick W., Zhang, Peiyi, Wiegand, Janet, Zhang, Xuan, Budamagunta, Vivekananda, Sobh, Amin, Tagmount, Abderrahmane, Loguinov, Alexander, Riner, Andrea N., Akki, Ashwin S., Williamson, Elizabeth, Hromas, Robert, Vulpe, Christopher D., Zheng, Guangrong, Trevino, Jose G., Zhou, Daohong
Publicado 2022

XP-524 is a dual-BET/EP300 inhibitor that represses oncogenic KRAS and potentiates immune checkpoint inhibition in pancreatic cancer

por Principe, Daniel R., Xiong, Rui, Li, Yangfeng, Pham, Thao N. D., Kamath, Suneel D., Dubrovskyi, Oleksii, Ratia, Kiira, Huang, Fei, Zhao, Jiong, Shen, Zhengnan, Thummuri, Dinesh, Daohong, Zhou, Underwood, Patrick W., Trevino, Jose, Munshi, Hidayatullah G., Thatcher, Gregory R. J., Rana, Ajay
Publicado 2022