Potent anti-leukemic activity of a specific cyclin-dependent kinase 9 inhibitor in mouse models of chronic lymphocytic leukemia

por Göthert, Joachim R., Imsak, Roze, Möllmann, Michael, Kesper, Stefanie, Göbel, Maria, Dührsen, Ulrich, Scholz, Arne, Lücking, Ulrich, Baumann, Matthias, Unger, Anke, Schultz-Fademrecht, Carsten, Klebl, Bert, Eickhoff, Jan, Choidas, Axel, Dürig, Jan
Publicado 2018

Synthesis and Development of Highly Selective Pyrrolo[2,3-d]pyrimidine CSF1R Inhibitors Targeting the Autoinhibited Form

por Aarhus, Thomas Ihle, Bjørnstad, Frithjof, Wolowczyk, Camilla, Larsen, Kristin Uhlving, Rognstad, Line, Leithaug, Trygve, Unger, Anke, Habenberger, Peter, Wolf, Alexander, Bjørkøy, Geir, Pridans, Clare, Eickhoff, Jan, Klebl, Bert, Hoff, Bård H., Sundby, Eirik
Publicado 2023

Structure–Activity Relationship Studies of Trisubstituted Isoxazoles as Selective Allosteric Ligands for the Retinoic-Acid-Receptor-Related Orphan Receptor γt

por Meijer, Femke A., Saris, Annet O.W.M., Doveston, Richard G., Oerlemans, Guido J.M., de Vries, Rens M.J.M., Somsen, Bente A., Unger, Anke, Klebl, Bert, Ottmann, Christian, Cossar, Peter J., Brunsveld, Luc
Publicado 2021

Protection of pancreatic islets from oxidative cell death by a peripherally-active morphinan with increased drug safety

por Scholz, Okka, Huß, Elena, Otter, Silke, Herebian, Diran, Hamacher, Anna, Levy, Laura Mariana, Hristeva, Stanimira, Sanz, Miguel, Ajani, Haresh, Puentes, Alfredo Rodriguez, Hoffmann, Torsten, Hogeback, Jens, Unger, Anke, Terheyden, Susanne, Reina do Fundo, Michelle, Dewidar, Bedair, Roden, Michael, Lammert, Eckhard
Publicado 2023

TRPC4/TRPC5 channels mediate adverse reaction to the cancer cell cytotoxic agent (-)-Englerin A

por Cheung, Sin Ying, Henrot, Matthias, Al-Saad, Mohammad, Baumann, Matthias, Muller, Heiko, Unger, Anke, Rubaiy, Hussein N., Mathar, Ilka, Dinkel, Klaus, Nussbaumer, Peter, Klebl, Bert, Freichel, Marc, Rode, Baptiste, Trainor, Sebastian, Clapcote, Steven J., Christmann, Mathias, Waldmann, Herbert, Abbas, Syed Khawar, Beech, David J., Vasudev, Naveen S.
Publicado 2018

Inhibition of osimertinib-resistant epidermal growth factor receptor EGFR-T790M/C797S

por Lategahn, Jonas, Keul, Marina, Klövekorn, Philip, Tumbrink, Hannah L., Niggenaber, Janina, Müller, Matthias P., Hodson, Luke, Flaßhoff, Maren, Hardick, Julia, Grabe, Tobias, Engel, Julian, Schultz-Fademrecht, Carsten, Baumann, Matthias, Ketzer, Julia, Mühlenberg, Thomas, Hiller, Wolf, Günther, Georgia, Unger, Anke, Müller, Heiko, Heimsoeth, Alena, Golz, Christopher, Blank-Landeshammer, Bernhard, Kollipara, Laxmikanth, Zahedi, René P., Strohmann, Carsten, Hengstler, Jan G., van Otterlo, Willem A. L., Bauer, Sebastian, Rauh, Daniel
Publicado 2019