Effects of Tablet Formulation, Food, or Gastric pH on the Bioavailability of Asundexian

por Kanefendt, Friederike, Brase, Christine, Unger, Sigrun, Kubitza, Dagmar
Publicado 2022

Pharmacokinetics of the soluble guanylate cyclase stimulator riociguat in individuals with renal impairment

por Frey, Reiner, Becker, Corina, Unger, Sigrun, Schmidt, Anja, Wensing, Georg, Mueck, Wolfgang
Publicado 2013

Pharmacokinetics of the soluble guanylate cyclase stimulator riociguat in individuals with hepatic impairment

por Frey, Reiner, Becker, Corina, Unger, Sigrun, Schmidt, Anja, Wensing, Georg, Mueck, Wolfgang
Publicado 2013

Absorption behavior of riociguat: bioavailability, food effects, and dose-proportionality

por Becker, Corina, Frey, Reiner, Hesse, Christiane, Unger, Sigrun, Reber, Michael, Mueck, Wolfgang
Publicado 2013

Bioavailability, pharmacokinetics and safety of riociguat given as an oral suspension or crushed tablet with and without food

por Saleh, Soundos, Frey, Reiner, Becker, Corina, Unger, Sigrun, Wensing, Georg, Mück, Wolfgang
Publicado 2015

First evaluation of the safety, pharmacokinetics, and pharmacodynamics of BAY 2433334, a small molecule targeting coagulation factor XIa

por Thomas, Dirk, Kanefendt, Friederike, Schwers, Stephan, Unger, Sigrun, Yassen, Ashraf, Boxnick, Stefanie
Publicado 2021

Effects of omeprazole and AlOH/MgOH on riociguat absorption

por Becker, Corina, Frey, Reiner, Unger, Sigrun, Artmeier-Brandt, Ulrike, Weimann, Gerrit, Mueck, Wolfgang
Publicado 2013

No pharmacodynamic (PD) and pharmacokinetic (PK) interaction of riociguat (BAY 63-2521) and aspirin

por Frey, Reiner, Mück, Wolfgang, Unger, Sigrun, Reber, Michael, Krätzschmar, Jörn, Becker, Corina, Wensing, Georg
Publicado 2011

Clinical Pharmacokinetic and Pharmacodynamic Profile of Riociguat

por Frey, Reiner, Becker, Corina, Saleh, Soundos, Unger, Sigrun, van der Mey, Dorina, Mück, Wolfgang
Publicado 2017

BAY 1213790, a fully human IgG1 antibody targeting coagulation factor XIa: First evaluation of safety, pharmacodynamics, and pharmacokinetics

por Thomas, Dirk, Thelen, Kirstin, Kraff, Stefanie, Schwers, Stephan, Schiffer, Sonja, Unger, Sigrun, Yassen, Ashraf, Boxnick, Stefanie
Publicado 2019

Pharmacokinetic interaction of ketoconazole, clarithromycin, and midazolam with riociguat

por Becker, Corina, Frey, Reiner, Unger, Sigrun, Thomas, Dirk, Reber, Michael, Weimann, Gerrit, Dietrich, Hartmut, Arens, Erich R, Mueck, Wolfgang
Publicado 2013

Pharmacokinetic interaction of riociguat and antiretroviral combination regimens in HIV-1-infected adults

por DeJesus, Edwin, Saleh, Soundos, Cheng, Sue, van der Mey, Dorina, Becker, Corina, Frey, Reiner, Unger, Sigrun, Mueck, Wolfgang
Publicado 2019

Acute Hemodynamic Effects of Riociguat in Patients With Pulmonary Hypertension Associated With Diastolic Heart Failure (DILATE-1): A Randomized, Double-Blind, Placebo-Controlled, S...

por Bonderman, Diana, Pretsch, Ingrid, Steringer-Mascherbauer, Regina, Jansa, Pavel, Rosenkranz, Stephan, Tufaro, Caroline, Bojic, Andja, Lam, Carolyn S. P., Frey, Reiner, Ochan Kilama, Michael, Unger, Sigrun, Roessig, Lothar, Lang, Irene M.
Publicado 2014

BAY 2253651 for the treatment of obstructive sleep apnoea: a multicentre, double-blind, randomised controlled trial (SANDMAN)

por Gaisl, Thomas, Turnbull, Chris D., Weimann, Gerrit, Unger, Sigrun, Finger, Rudolf, Xing, Charles, Cistulli, Peter A., West, Sophie, Chiang, Alan K.I., Eckert, Danny J., Stradling, John R., Kohler, Malcolm
Publicado 2021