Selinexor synergizes with dexamethasone to repress mTORC1 signaling and induce multiple myeloma cell death

por Argueta, Christian, Kashyap, Trinayan, Klebanov, Boris, Unger, Thaddeus J., Guo, Cathy, Harrington, Susie, Baloglu, Erkan, Lee, Margaret, Senapedis, William, Shacham, Sharon, Landesman, Yosef
Publicado 2018

Selinexor reduces the expression of DNA damage repair proteins and sensitizes cancer cells to DNA damaging agents

por Kashyap, Trinayan, Argueta, Christian, Unger, Thaddeus, Klebanov, Boris, Debler, Sophia, Senapedis, William, Crochiere, Marsha L., Lee, Margaret S., Kauffman, Michael, Shacham, Sharon, Landesman, Yosef
Publicado 2018

Selinexor, a Selective Inhibitor of Nuclear Export (SINE) compound, acts through NF-κB deactivation and combines with proteasome inhibitors to synergistically induce tumor cell dea...

por Kashyap, Trinayan, Argueta, Christian, Aboukameel, Amro, Unger, Thaddeus John, Klebanov, Boris, Mohammad, Ramzi M., Muqbil, Irfana, Azmi, Asfar S., Drolen, Claire, Senapedis, William, Lee, Margaret, Kauffman, Michael, Shacham, Sharon, Landesman, Yosef
Publicado 2016

Activation of TrkB with TAM-163 Results in Opposite Effects on Body Weight in Rodents and Non-Human Primates

por Perreault, Mylène, Feng, Guo, Will, Sarah, Gareski, Tiffany, Kubasiak, David, Marquette, Kimberly, Vugmeyster, Yulia, Unger, Thaddeus J., Jones, Juli, Qadri, Ariful, Hahm, Seung, Sun, Ying, Rohde, Cynthia M., Zwijnenberg, Raphael, Paulsen, Janet, Gimeno, Ruth E.
Publicado 2013