Cysteine in cell culture media induces acidic IgG1 species by disrupting the disulfide bond network

por Prade, Elke, Zeck, Anne, Stiefel, Fabian, Unsoeld, Andreas, Mentrup, David, Arango Gutierrez, Erik, Gorr, Ingo H.
Publicado 2020

Application of metabolic modeling for targeted optimization of high seeding density processes

por Brunner, Matthias, Kolb, Klara, Keitel, Alena, Stiefel, Fabian, Wucherpfennig, Thomas, Bechmann, Jan, Unsoeld, Andreas, Schaub, Jochen
Publicado 2021

Towards robust cell culture processes — Unraveling the impact of media preparation by spectroscopic online monitoring

por Brunner, Matthias, Brosig, Philipp, Losing, Monika, Kunzelmann, Marco, Calvet, Amandine, Stiefel, Fabian, Bechmann, Jan, Unsoeld, Andreas, Schaub, Jochen
Publicado 2019