Pim Kinases: Important Regulators of Cardiovascular Disease

por Nock, Sophie, Karim, Eima, Unsworth, Amanda J.
Publicado 2023

The Benefits of Using Case Study Focussed, Problem Based Learning Approaches to Unit Design for Biomedical Science Students

por Posner, Mareike G., Dempsey, Nina C., Unsworth, Amanda J.
Publicado 2023

Non-genomic effects of nuclear receptors: insights from the anucleate platelet

por Unsworth, Amanda J, Flora, Gagan D, Gibbins, Jonathan M
Publicado 2018

The Contribution of Vascular Proteoglycans to Atherothrombosis: Clinical Implications

por Drysdale, Amelia, Unsworth, Amanda J., White, Stephen J., Jones, Sarah
Publicado 2023

Submaximal Inhibition of Protein Kinase C Restores ADP-induced Dense Granule Secretion in Platelets in the Presence of Ca(2+)

por Unsworth, Amanda J., Smith, Holly, Gissen, Paul, Watson, Steve P., Pears, Catherine J.
Publicado 2011

Cobimetinib and trametinib inhibit platelet MEK but do not cause platelet dysfunction

por Unsworth, Amanda J., Bye, Alexander P., Kriek, Neline, Sage, Tanya, Osborne, Ashley A., Donaghy, Dillon, Gibbins, Jonathan M.
Publicado 2018

RXR Ligands Negatively Regulate Thrombosis and Hemostasis

por Unsworth, Amanda J., Flora, Gagan D., Sasikumar, Parvathy, Bye, Alexander P., Sage, Tanya, Kriek, Neline, Crescente, Marilena, Gibbins, Jonathan M.
Publicado 2017

Delineating Zinc Influx Mechanisms during Platelet Activation

por Kuravi, Sahithi J., Ahmed, Niaz S., Taylor, Kirk A., Capes, Emily M., Bye, Alex, Unsworth, Amanda J., Gibbins, Jonathan M., Pugh, Nicholas
Publicado 2023

The Metabolites of the Dietary Flavonoid Quercetin Possess Potent Antithrombotic Activity, and Interact with Aspirin to Enhance Antiplatelet Effects

por Stainer, Alexander R., Sasikumar, Parvathy, Bye, Alexander P., Unsworth, Amanda J., Holbrook, Lisa M., Tindall, Marcus, Lovegrove, Julie A., Gibbins, Jonathan M.
Publicado 2019

Pharmacological actions of nobiletin in the modulation of platelet function

por Vaiyapuri, Sakthivel, Roweth, Harvey, Ali, Marfoua S, Unsworth, Amanda J, Stainer, Alexander R, Flora, Gagan D, Crescente, Marilena, Jones, Chris I, Moraes, Leonardo A, Gibbins, Jonathan M
Publicado 2015

Human Platelet Protein Ubiquitylation and Changes following GPVI Activation

por Unsworth, Amanda J., Bombik, Izabela, Pinto-Fernandez, Adan, McGouran, Joanna F., Konietzny, Rebecca, Zahedi, René P., Watson, Steve P., Kessler, Benedikt M., Pears, Catherine J.
Publicado 2019

Non-genomic effects of the Pregnane X Receptor negatively regulate platelet functions, thrombosis and haemostasis

por Flora, Gagan D., Sahli, Khaled A., Sasikumar, Parvathy, Holbrook, Lisa-Marie, Stainer, Alexander R., AlOuda, Sarah K., Crescente, Marilena, Sage, Tanya, Unsworth, Amanda J., Gibbins, Jonathan M.
Publicado 2019

Maternal and offspring high-fat diet leads to platelet hyperactivation in male mice offspring

por Gaspar, Renato S., Unsworth, Amanda J., Al-Dibouni, Alaa, Bye, Alexander P., Sage, Tanya, Stewart, Michelle, Wells, Sara, Cox, Roger D., Gibbins, Jonathan M., Sellayah, Dyan, E. Hughes, Craig
Publicado 2021

Cucurbitacins Elicit Anti-Platelet Activity via Perturbation of the Cytoskeleton and Integrin Function

por Kriek, Neline, Nock, Sophie H., Sage, Tanya, Khalifa, Badrija, Bye, Alexander P., Mitchell, Joanne L., Thomson, Steven, McLaughlin, Mark G., Jones, Sarah, Gibbins, Jonathan M., Unsworth, Amanda J.
Publicado 2022

Farnesoid X Receptor and Liver X Receptor Ligands Initiate Formation of Coated Platelets

por Unsworth, Amanda J., Bye, Alexander P., Tannetta, Dionne S., Desborough, Michael J.R., Kriek, Neline, Sage, Tanya, Allan, Harriet E., Crescente, Marilena, Yaqoob, Parveen, Warner, Timothy D., Jones, Chris I., Gibbins, Jonathan M.
Publicado 2017

Multiparameter phenotyping of platelet reactivity for stratification of human cohorts

por Dunster, Joanne L., Bye, Alexander P., Kriek, Neline, Sage, Tanya, Mitchell, Joanne L., Kempster, Carly, Batista, Joana, McKinney, Harriet, Thomas, Patrick, Jones, Chris I., Downes, Kate, Unsworth, Amanda J., Gibbins, Jonathan M.
Publicado 2021

Antiplatelet properties of Pim kinase inhibition are mediated through disruption of thromboxane A2 receptor signaling

por Unsworth, Amanda J., Bye, Alexander P., Sage, Tanya, Gaspar, Renato S., Eaton, Nathan, Drew, Caleb, Stainer, Alexander, Kriek, Neline, Volberding, Peter J., Hutchinson, James L., Riley, Ryan, Jones, Sarah, Mundell, Stuart J., Cui, Weiguo, Falet, Hervé, Gibbins, Jonathan M.
Publicado 2020

Interspecies differences in protein expression do not impact the spatiotemporal regulation of glycoprotein VI mediated activation

por Dunster, Joanne L., Unsworth, Amanda J., Bye, Alexander P., Haining, Elizabeth J., Sowa, Marcin A., Di, Ying, Sage, Tanya, Pallini, Chiara, Pike, Jeremy A., Hardy, Alexander T., Nieswandt, Bernhard, García, Ángel, Watson, Steve P., Poulter, Natalie S., Gibbins, Jonathan M., Pollitt, Alice Y.
Publicado 2019

Platelet factor XIII-A regulates platelet function and promotes clot retraction and stability

por Mitchell, Joanne L., Little, Gemma, Bye, Alexander P., Gaspar, Renato S., Unsworth, Amanda J., Kriek, Neline, Sage, Tanya, Stainer, Alexander, Sangowawa, Ibidayo, Morrow, Gael B., Bastos, Ricardo N., Shapiro, Susan, Desborough, Michael J.R., Curry, Nicola, Gibbins, Jonathan M., Whyte, Claire S., Mutch, Nicola J., Jones, Christopher I.
Publicado 2023