The impact of hepatic and renal function on panitumumab exposures in patients with metastatic RAS wild-type colorectal cancer

por Liao, Michael Z., Prenen, Hans, Dutta, Sandeep, Upreti, Vijay V.
Publicado 2021

Dose Regimen Rationale for Panitumumab in Cancer Patients: To Be Based on Body Weight or Not

por Liao, Michael Z, Berkhout, Marloes, Prenen, Hans, Dutta, Sandeep, Upreti, Vijay V
Publicado 2020

Is Bodyweight-Based Dosing Truly Better Than Flat Dosing for Panitumumab? [Response to Letter]

por Liao, Michael Z, Kast, Johannes, Berkhout, Marloes, Prenen, Hans, Dutta, Sandeep, Upreti, Vijay V
Publicado 2020

Oncolytic viral kinetics mechanistic modeling of Talimogene Laherparepvec (T‐VEC) a first‐in‐class oncolytic viral therapy in patients with advanced melanoma

por Ahamadi, Malidi, Kast, Johannes, Chen, Po‐Wei, Huang, Xiaojun, Dutta, Sandeep, Upreti, Vijay V.
Publicado 2023

Mechanistic Pharmacokinetic/Pharmacodynamic Modeling in Support of a Patient-Convenient, Longer Dosing Interval for Carfilzomib, a Covalent Inhibitor of the Proteasome

por Yago, Marc R., Mehta, Khamir, Bose, Maitreyee, Bhagwat, Sharvari, Chopra, Vivek S., Dutta, Sandeep, Upreti, Vijay V.
Publicado 2023

Recent advances and clinical pharmacology aspects of Chimeric Antigen Receptor (CAR) T‐cellular therapy development

por Kast, Johannes, Nozohouri, Saeideh, Zhou, Di, Yago, Marc R., Chen, Po‐Wei, Ahamadi, Malidi, Dutta, Sandeep, Upreti, Vijay V.
Publicado 2022

Effect of famotidine on the pharmacokinetics of apixaban, an oral direct factor Xa inhibitor

por Upreti, Vijay V, Song, Yan, Wang, Jessie, Byon, Wonkyung, Boyd, Rebecca A, Pursley, Janice M, LaCreta, Frank, Frost, Charles E
Publicado 2013

Dose escalation results from a first-in-human, phase 1 study of glucocorticoid-induced TNF receptor–related protein agonist AMG 228 in patients with advanced solid tumors

por Tran, Ben, Carvajal, Richard D., Marabelle, Aurelien, Patel, Sandip Pravin, LoRusso, Patricia M., Rasmussen, Erik, Juan, Gloria, Upreti, Vijay V., Beers, Courtney, Ngarmchamnanrith, Gataree, Schöffski, Patrick
Publicado 2018

Targeting wild-type TP53 using AMG 232 in combination with MAPK inhibition in Metastatic Melanoma; a phase 1 study

por Moschos, Stergios J., Sandhu, Shahneen, Lewis, Karl D., Sullivan, Ryan J., Puzanov, Igor, Johnson, Douglas B., Henary, Haby A., Wong, Hansen, Upreti, Vijay V., Long, Georgina V., Flaherty, Keith T.
Publicado 2022

Recommendations for the Design of Clinical Drug–Drug Interaction Studies With Itraconazole Using a Mechanistic Physiologically‐Based Pharmacokinetic Model

por Chen, Yuan, Cabalu, Tamara D., Callegari, Ernesto, Einolf, Heidi, Liu, Lichuan, Parrott, Neil, Peters, Sheila Annie, Schuck, Edgar, Sharma, Pradeep, Tracey, Helen, Upreti, Vijay V., Zheng, Ming, Zhu, Andy Z.X., Hall, Stephen D.
Publicado 2019

Physiologically‐Based Pharmacokinetic Modeling in Renal and Hepatic Impairment Populations: A Pharmaceutical Industry Perspective

por Heimbach, Tycho, Chen, Yuan, Chen, Jun, Dixit, Vaishali, Parrott, Neil, Peters, Sheila Annie, Poggesi, Italo, Sharma, Pradeep, Snoeys, Jan, Shebley, Mohamad, Tai, Guoying, Tse, Susanna, Upreti, Vijay V., Wang, Ying‐Hong, Tsai, Alice, Xia, Binfeng, Zheng, Ming, Zhu, Andy Z.X., Hall, Stephen
Publicado 2020

Industrial Perspective on the Benefits Realized From the FDA’s Model‐Informed Drug Development Paired Meeting Pilot Program

por Galluppi, Gerald R., Brar, Satjit, Caro, Luzelena, Chen, Yuan, Frey, Nicolas, Grimm, Hans Peter, Rudd, Deanne Jackson, Li, Chi‐Chung, Magee, Mindy, Mukherjee, Arnab, Nagao, Lee, Purohit, Vivek S., Roy, Amit, Salem, Ahmed Hamed, Sinha, Vikram, Suleiman, Ahmed A., Taskar, Kunal S., Upreti, Vijay V., Weber, Benjamin, Cook, Jack
Publicado 2021

Immunogenicity assessment of AAV-based gene therapies: An IQ consortium industry white paper

por Yang, Tong-yuan, Braun, Manuela, Lembke, Wibke, McBlane, Fraser, Kamerud, John, DeWall, Stephen, Tarcsa, Edit, Fang, Xiaodong, Hofer, Lena, Kavita, Uma, Upreti, Vijay V., Gupta, Swati, Loo, LiNa, Johnson, Alison J., Chandode, Rakesh Kantilal, Stubenrauch, Kay-Gunnar, Vinzing, Maya, Xia, Cindy Q., Jawa, Vibha
Publicado 2022