Structure-Function Analysis of the Anopheles gambiae LRIM1/APL1C Complex and its Interaction with Complement C3-Like Protein TEP1

por Povelones, Michael, Upton, Leanna M., Sala, Katarzyna A., Christophides, George K.
Publicado 2011

Fueling Open Innovation for Malaria Transmission-Blocking Drugs: Hundreds of Molecules Targeting Early Parasite Mosquito Stages

por Delves, Michael, Lafuente-Monasterio, M. Jose, Upton, Leanna, Ruecker, Andrea, Leroy, Didier, Gamo, Francisco-Javier, Sinden, Robert
Publicado 2019

The CLIP-Domain Serine Protease Homolog SPCLIP1 Regulates Complement Recruitment to Microbial Surfaces in the Malaria Mosquito Anopheles gambiae

por Povelones, Michael, Bhagavatula, Lavanya, Yassine, Hassan, Tan, Lee Aun, Upton, Leanna M., Osta, Mike A., Christophides, George K.
Publicado 2013

A novel model fitted to multiple life stages of malaria for assessing efficacy of transmission-blocking interventions

por Sherrard-Smith, Ellie, Churcher, Thomas S., Upton, Leanna M., Sala, Katarzyna A., Zakutansky, Sara E., Slater, Hannah C., Blagborough, Andrew M., Betancourt, Michael
Publicado 2017

Synergy in anti-malarial pre-erythrocytic and transmission-blocking antibodies is achieved by reducing parasite density

por Sherrard-Smith, Ellie, Sala, Katarzyna A, Betancourt, Michael, Upton, Leanna M, Angrisano, Fiona, Morin, Merribeth J, Ghani, Azra C, Churcher, Thomas S, Blagborough, Andrew M
Publicado 2018

Probability of Transmission of Malaria from Mosquito to Human Is Regulated by Mosquito Parasite Density in Naïve and Vaccinated Hosts

por Churcher, Thomas S., Sinden, Robert E., Edwards, Nick J., Poulton, Ian D., Rampling, Thomas W., Brock, Patrick M., Griffin, Jamie T., Upton, Leanna M., Zakutansky, Sara E., Sala, Katarzyna A., Angrisano, Fiona, Hill, Adrian V. S., Blagborough, Andrew M.
Publicado 2017

A novel multiple-stage antimalarial agent that inhibits protein synthesis

por Baragaña, Beatriz, Hallyburton, Irene, Lee, Marcus C. S., Norcross, Neil R., Grimaldi, Raffaella, Otto, Thomas D., Proto, William R., Blagborough, Andrew M., Meister, Stephan, Wirjanata, Grennady, Ruecker, Andrea, Upton, Leanna M., Abraham, Tara S., Almeida, Mariana J., Pradhan, Anupam, Porzelle, Achim, Martínez, María Santos, Bolscher, Judith M., Woodland, Andrew, Norval, Suzanne, Zuccotto, Fabio, Thomas, John, Simeons, Frederick, Stojanovski, Laste, Osuna-Cabello, Maria, Brock, Paddy M., Churcher, Tom S., Sala, Katarzyna A., Zakutansky, Sara E., Jiménez-Díaz, María Belén, Sanz, Laura Maria, Riley, Jennifer, Basak, Rajshekhar, Campbell, Michael, Avery, Vicky M., Sauerwein, Robert W, Dechering, Koen J., Noviyanti, Rintis, Campo, Brice, Frearson, Julie A., Angulo-Barturen, Iñigo, Ferrer-Bazaga, Santiago, Gamo, Francisco Javier, Wyatt, Paul G., Leroy, Didier, Siegl, Peter, Delves, Michael J., Kyle, Dennis E., Wittlin, Sergio, Marfurt, Jutta, Price, Ric N., Sinden, Robert E., Winzeler, Elizabeth, Charman, Susan A., Bebrevska, Lidiya, Gray, David W., Campbell, Simon, Fairlamb, Alan H., Willis, Paul, Rayner, Julian C., Fidock, David A., Read, Kevin D., Gilbert, Ian H.
Publicado 2015