Granzyme A Is Expressed in Mouse Lungs during Mycobacterium tuberculosis Infection but Does Not Contribute to Protection In Vivo

por Uranga, Santiago, Marinova, Dessislava, Martin, Carlos, Pardo, Julián, Aguilo, Nacho
Publicado 2016

MTBVAC vaccine is safe, immunogenic and confers protective efficacy against Mycobacterium tuberculosis in newborn mice

por Aguilo, Nacho, Uranga, Santiago, Marinova, Dessislava, Monzon, Marta, Badiola, Juan, Martin, Carlos
Publicado 2016

Therapeutic efficacy of pulmonary live tuberculosis vaccines against established asthma by subverting local immune environment

por Tarancón, Raquel, Mata, Elena, Uranga, Santiago, Gómez, Ana Belén, Marinova, Dessislava, Otal, Isabel, Martín, Carlos, Aguiló, Nacho
Publicado 2021

New insights into the transposition mechanisms of IS6110 and its dynamic distribution between Mycobacterium tuberculosis Complex lineages

por Gonzalo-Asensio, Jesús, Pérez, Irene, Aguiló, Nacho, Uranga, Santiago, Picó, Ana, Lampreave, Carlos, Cebollada, Alberto, Otal, Isabel, Samper, Sofía, Martín, Carlos
Publicado 2018

Live attenuated TB vaccines representing the three modern Mycobacterium tuberculosis lineages reveal that the Euro–American genetic background confers optimal vaccine potential

por Pérez, Irene, Uranga, Santiago, Sayes, Fadel, Frigui, Wafa, Samper, Sofía, Arbués, Ainhoa, Aguiló, Nacho, Brosch, Roland, Martín, Carlos, Gonzalo-Asensio, Jesús
Publicado 2020

Engineering a new vaccine platform for heterologous antigen delivery in live-attenuated Mycobacterium tuberculosis

por Broset, Esther, Calvet Seral, Juan, Arnal, Carmen, Uranga, Santiago, Kanno, Alex I., Leite, Luciana C.C., Martín, Carlos, Gonzalo-Asensio, Jesús
Publicado 2021

The Mycobacterium tuberculosis PhoPR virulence system regulates expression of the universal second messenger c-di-AMP and impacts vaccine safety and efficacy

por Pérez, Irene, Campos-Pardos, Elena, Díaz, Caridad, Uranga, Santiago, Sayes, Fadel, Vicente, Francisca, Aguiló, Nacho, Brosch, Roland, Martín, Carlos, Gonzalo-Asensio, Jesús
Publicado 2022

MTBVAC-Based TB-HIV Vaccine Is Safe, Elicits HIV-T Cell Responses, and Protects against Mycobacterium tuberculosis in Mice

por Broset, Esther, Saubi, Narcís, Guitart, Núria, Aguilo, Nacho, Uranga, Santiago, Kilpeläinen, Athina, Eto, Yoshiki, Hanke, Tomáš, Gonzalo-Asensio, Jesús, Martín, Carlos, Joseph-Munné, Joan
Publicado 2019

Reactogenicity to major tuberculosis antigens absent in BCG is linked to improved protection against Mycobacterium tuberculosis

por Aguilo, Nacho, Gonzalo-Asensio, Jesus, Alvarez-Arguedas, Samuel, Marinova, Dessislava, Gomez, Ana Belen, Uranga, Santiago, Spallek, Ralf, Singh, Mahavir, Audran, Regine, Spertini, François, Martin, Carlos
Publicado 2017

Independent genomic polymorphisms in the PknH serine threonine kinase locus during evolution of the Mycobacterium tuberculosis Complex affect virulence and host preference

por Mata, Elena, Farrell, Damien, Ma, Ruoyao, Uranga, Santiago, Gomez, Ana Belen, Monzon, Marta, Badiola, Juan, Anel, Alberto, Gonzalo-Asensio, Jesús, Martin, Carlos, Gordon, Stephen V., Aguilo, Nacho
Publicado 2020

New live attenuated tuberculosis vaccine MTBVAC induces trained immunity and confers protection against experimental lethal pneumonia

por Tarancón, Raquel, Domínguez-Andrés, Jorge, Uranga, Santiago, Ferreira, Anaísa V., Groh, Laszlo A., Domenech, Mirian, González-Camacho, Fernando, Riksen, Niels P., Aguilo, Nacho, Yuste, José, Martín, Carlos, Netea, Mihai G.
Publicado 2020

Novel intravesical bacterial immunotherapy induces rejection of BCG-unresponsive established bladder tumors

por Moreo, Eduardo, Uranga, Santiago, Picó, Ana, Gómez, Ana Belén, Nardelli-Haefliger, Denise, del Fresno, Carlos, Murillo, Ingrid, Puentes, Eugenia, Rodríguez, Esteban, Vales-Gómez, Mar, Pardo, Julian, Sancho, David, Martín, Carlos, Aguilo, Nacho
Publicado 2022

Respiratory Immunization With a Whole Cell Inactivated Vaccine Induces Functional Mucosal Immunoglobulins Against Tuberculosis in Mice and Non-human Primates

por Aguilo, Nacho, Uranga, Santiago, Mata, Elena, Tarancon, Raquel, Gómez, Ana Belén, Marinova, Dessislava, Otal, Isabel, Monzón, Marta, Badiola, Juan, Montenegro, Dolores, Puentes, Eugenia, Rodríguez, Esteban, Vervenne, Richard A. W., Sombroek, Claudia C., Verreck, Frank A. W., Martín, Carlos
Publicado 2020

Intravenous administration of BCG in mice promotes natural killer and T cell-mediated antitumor immunity in the lung

por Moreo, Eduardo, Jarit-Cabanillas, Aitor, Robles-Vera, Iñaki, Uranga, Santiago, Guerrero, Claudia, Gómez, Ana Belén, Mata-Martínez, Pablo, Minute, Luna, Araujo-Voces, Miguel, Felgueres, María José, Esteso, Gloria, Uranga-Murillo, Iratxe, Arias, Maykel, Pardo, Julián, Martín, Carlos, Valés-Gómez, Mar, del Fresno, Carlos, Sancho, David, Aguiló, Nacho
Publicado 2023