Pluripotent epigenetic regulator OBP-801 maintains filtering blebs in glaucoma filtration surgery model

por Yamamoto, Yuji, Mukai, Atsushi, Ikushima, Toru, Urata, Yasuo, Kinoshita, Shigeru, Hamuro, Junji, Ueno, Morio, Sotozono, Chie
Publicado 2020

Adenoviral targeting of malignant melanoma for fluorescence-guided surgery prevents recurrence in orthotopic nude-mouse models

por Yano, Shuya, Takehara, Kiyoto, Kishimoto, Hiroyuki, Urata, Yasuo, Kagawa, Shunsuke, Bouvet, Michael, Fujiwara, Toshiyoshi, Hoffman, Robert M.
Publicado 2015

Efficacy of a Cell-Cycle Decoying Killer Adenovirus on 3-D Gelfoam(®)-Histoculture and Tumor-Sphere Models of Chemo-Resistant Stomach Carcinomatosis Visualized by FUCCI Imaging

por Yano, Shuya, Takehara, Kiyoto, Tazawa, Hiroshi, Kishimoto, Hiroyuki, Urata, Yasuo, Kagawa, Shunsuke, Fujiwara, Toshiyoshi, Hoffman, Robert M.
Publicado 2016

Precise navigation surgery of tumours in the lung in mouse models enabled by in situ fluorescence labelling with a killer-reporter adenovirus

por Yano, Shuya, Zhang, Yong, Miwa, Shinji, Kishimoto, Hiroyuki, Urata, Yasuo, Bouvet, Michael, Kagawa, Shunsuke, Fujiwara, Toshiyoshi, Hoffman, Robert M
Publicado 2015

Tumor-targeting adenovirus OBP-401 inhibits primary and metastatic tumor growth of triple-negative breast cancer in orthotopic nude-mouse models

por Yano, Shuya, Takehara, Kiyoto, Kishimoto, Hiroyuki, Tazawa, Hiroshi, Urata, Yasuo, Kagawa, Shunsuke, Bouvet, Michael, Fujiwara, Toshiyoshi, Hoffman, Robert M.
Publicado 2016

p53-armed oncolytic adenovirus induces autophagy and apoptosis in KRAS and BRAF-mutant colorectal cancer cells

por Tamura, Shuta, Tazawa, Hiroshi, Hori, Naoto, Li, Yuncheng, Yamada, Motohiko, Kikuchi, Satoru, Kuroda, Shinji, Urata, Yasuo, Kagawa, Shunsuke, Fujiwara, Toshiyoshi
Publicado 2023

The hTERT Promoter Enhances the Antitumor Activity of an Oncolytic Adenovirus under a Hypoxic Microenvironment

por Hashimoto, Yuuri, Tazawa, Hiroshi, Teraishi, Fuminori, Kojima, Toru, Watanabe, Yuichi, Uno, Futoshi, Yano, Shuya, Urata, Yasuo, Kagawa, Shunsuke, Fujiwara, Toshiyoshi
Publicado 2012

Elimination of MYCN-Amplified Neuroblastoma Cells by Telomerase-Targeted Oncolytic Virus via MYCN Suppression

por Tanimoto, Terutaka, Tazawa, Hiroshi, Ieda, Takeshi, Nouso, Hiroshi, Tani, Morimichi, Oyama, Takanori, Urata, Yasuo, Kagawa, Shunsuke, Noda, Takuo, Fujiwara, Toshiyoshi
Publicado 2020

Fluorescence-guided surgery of a highly-metastatic variant of human triple-negative breast cancer targeted with a cancer-specific GFP adenovirus prevents recurrence

por Yano, Shuya, Takehara, Kiyoto, Miwa, Shinji, Kishimoto, Hiroyuki, Tazawa, Hiroshi, Urata, Yasuo, Kagawa, Shunsuke, Bouvet, Michael, Fujiwara, Toshiyoshi, Hoffman, Robert M.
Publicado 2016

Boosting Replication and Penetration of Oncolytic Adenovirus by Paclitaxel Eradicate Peritoneal Metastasis of Gastric Cancer

por Ishikawa, Wataru, Kikuchi, Satoru, Ogawa, Toshihiro, Tabuchi, Motoyasu, Tazawa, Hiroshi, Kuroda, Shinji, Noma, Kazuhiro, Nishizaki, Masahiko, Kagawa, Shunsuke, Urata, Yasuo, Fujiwara, Toshiyoshi
Publicado 2020

Improved Resection and Outcome of Colon-Cancer Liver Metastasis with Fluorescence-Guided Surgery Using In Situ GFP Labeling with a Telomerase-Dependent Adenovirus in an Orthotopic...

por Yano, Shuya, Takehara, Kiyoto, Miwa, Shinji, Kishimoto, Hiroyuki, Hiroshima, Yukihiko, Murakami, Takashi, Urata, Yasuo, Kagawa, Shunsuke, Bouvet, Michael, Fujiwara, Toshiyoshi, Hoffman, Robert M.
Publicado 2016

Efficient detection of human circulating tumor cells without significant production of false-positive cells by a novel conditionally replicating adenovirus

por Sakurai, Fuminori, Narii, Nobuhiro, Tomita, Kyoko, Togo, Shinsaku, Takahashi, Kazuhisa, Machitani, Mitsuhiro, Tachibana, Masashi, Ouchi, Masaaki, Katagiri, Nobuyoshi, Urata, Yasuo, Fujiwara, Toshiyoshi, Mizuguchi, Hiroyuki
Publicado 2016

Modulation of p53 expression in cancer-associated fibroblasts prevents peritoneal metastasis of gastric cancer

por Ogawa, Toshihiro, Kikuchi, Satoru, Tabuchi, Motoyasu, Mitsui, Ema, Une, Yuta, Tazawa, Hiroshi, Kuroda, Shinji, Noma, Kazuhiro, Ohara, Toshiaki, Kagawa, Shunsuke, Urata, Yasuo, Fujiwara, Toshiyoshi
Publicado 2022

Sensitive detection of viable circulating tumor cells using a novel conditionally telomerase-selective replicating adenovirus in non-small cell lung cancer patients

por Togo, Shinsaku, Katagiri, Nobuyoshi, Namba, Yukiko, Tulafu, Miniwan, Nagahama, Kumi, Kadoya, Kotarou, Takamochi, Kazuya, Oh, Siaki, Suzuki, Kenji, Sakurai, Fuminori, Mizuguchi, Hiroyuki, Urata, Yasuo, Takahashi, Kazuhisa
Publicado 2017

Oncolytic virus-mediated p53 overexpression promotes immunogenic cell death and efficacy of PD-1 blockade in pancreatic cancer

por Araki, Hiroyuki, Tazawa, Hiroshi, Kanaya, Nobuhiko, Kajiwara, Yoshinori, Yamada, Motohiko, Hashimoto, Masashi, Kikuchi, Satoru, Kuroda, Shinji, Yoshida, Ryuichi, Umeda, Yuzo, Urata, Yasuo, Kagawa, Shunsuke, Fujiwara, Toshiyoshi
Publicado 2022

Targeting tumors with a killer-reporter adenovirus for curative fluorescence-guided surgery of soft-tissue sarcoma

por Yano, Shuya, Miwa, Shinji, Kishimoto, Hiroyuki, Uehara, Fuminari, Tazawa, Hiroshi, Toneri, Makoto, Hiroshima, Yukihiko, Yamamoto, Mako, Urata, Yasuo, Kagawa, Shunsuke, Bouvet, Michael, Fujiwara, Toshiyoshi, Hoffman, Robert M.
Publicado 2015

Tumor-specific delivery of biologics by a novel T-cell line HOZOT

por Onishi, Teppei, Tazawa, Hiroshi, Hashimoto, Yuuri, Takeuchi, Makoto, Otani, Takeshi, Nakamura, Shuji, Sakurai, Fuminori, Mizuguchi, Hiroyuki, Kishimoto, Hiroyuki, Umeda, Yuzo, Shirakawa, Yasuhiro, Urata, Yasuo, Kagawa, Shunsuke, Fujiwara, Toshiyoshi
Publicado 2016

Oncolytic Virus-Mediated Targeting of the ERK Signaling Pathway Inhibits Invasive Propensity in Human Pancreatic Cancer

por Koujima, Takeshi, Tazawa, Hiroshi, Ieda, Takeshi, Araki, Hiroyuki, Fushimi, Takuro, Shoji, Ryohei, Kuroda, Shinji, Kikuchi, Satoru, Yoshida, Ryuichi, Umeda, Yuzo, Teraishi, Fuminori, Urata, Yasuo, Mizuguchi, Hiroyuki, Fujiwara, Toshiyoshi
Publicado 2020

Oncolytic virotherapy promotes radiosensitivity in soft tissue sarcoma by suppressing anti-apoptotic MCL1 expression

por Omori, Toshinori, Tazawa, Hiroshi, Yamakawa, Yasuaki, Osaki, Shuhei, Hasei, Joe, Sugiu, Kazuhisa, Komatsubara, Tadashi, Fujiwara, Tomohiro, Yoshida, Aki, Kunisada, Toshiyuki, Urata, Yasuo, Kagawa, Shunsuke, Ozaki, Toshifumi, Fujiwara, Toshiyoshi
Publicado 2021

Ablation of MCL1 expression by virally induced microRNA-29 reverses chemoresistance in human osteosarcomas

por Osaki, Shuhei, Tazawa, Hiroshi, Hasei, Joe, Yamakawa, Yasuaki, Omori, Toshinori, Sugiu, Kazuhisa, Komatsubara, Tadashi, Fujiwara, Tomohiro, Sasaki, Tsuyoshi, Kunisada, Toshiyuki, Yoshida, Aki, Urata, Yasuo, Kagawa, Shunsuke, Ozaki, Toshifumi, Fujiwara, Toshiyoshi
Publicado 2016