In Vitro Phase I Metabolism of CRV431, a Novel Oral Drug Candidate for Chronic Hepatitis B

por Trepanier, Daniel J., Ure, Daren R., Foster, Robert T.
Publicado 2017

The Cyclophilin Inhibitor Rencofilstat Decreases HCV-induced Hepatocellular Carcinoma Independently of Its Antiviral Activity

por Stauffer, Winston, Bobardt, Michael, Ure, Daren, Foster, Robert, Gallay, Philippe
Publicado 2023

The Cyclophilin Inhibitor Rencofilstat Decreases HCV-Induced Hepatocellular Carcinoma Independently of Its Antiviral Activity

por Stauffer, Winston, Bobardt, Michael, Ure, Daren, Foster, Robert, Gallay, Philippe
Publicado 2023

Structurally distinct cyclosporin and sanglifehrin analogs CRV431 and NV556 suppress established HCV infection in humanized-liver mice

por Bobardt, Michael, Hansson, Magnus Joakim, Mayo, Patrick, Ure, Daren, Foster, Robert, Gallay, Philippe
Publicado 2020

The cyclophilin inhibitor CRV431 inhibits liver HBV DNA and HBsAg in transgenic mice

por Gallay, Philippe, Ure, Daren, Bobardt, Michael, Chatterji, Udayan, Ou, James, Trepanier, Daniel, Foster, Robert
Publicado 2019

The combination of the NS5A and cyclophilin inhibitors results in an additive anti-HCV inhibition in humanized mice without development of resistance

por Bobardt, Michael, Ramirez, Christina M., Baum, Marc M., Ure, Daren, Foster, Robert, Gallay, Philippe A.
Publicado 2021

The Novel Cyclophilin Inhibitor CPI-431-32 Concurrently Blocks HCV and HIV-1 Infections via a Similar Mechanism of Action

por Gallay, Philippe A., Bobardt, Michael D., Chatterji, Udayan, Trepanier, Daniel J., Ure, Daren, Ordonez, Cosme, Foster, Robert
Publicado 2015

A Pan-Cyclophilin Inhibitor, CRV431, Decreases Fibrosis and Tumor Development in Chronic Liver Disease Models

por Kuo, Joseph, Bobardt, Michael, Chatterji, Udayan, Mayo, Patrick R., Trepanier, Daniel J., Foster, Robert T., Gallay, Philippe, Ure, Daren R.
Publicado 2019

Differential Effects of Voclosporin and Tacrolimus on Insulin Secretion From Human Islets

por Kolic, Jelena, Beet, Leanne, Overby, Peter, Cen, Haoning Howard, Panzhinskiy, Evgeniy, Ure, Daren R, Cross, Jennifer L, Huizinga, Robert B, Johnson, James D
Publicado 2020

Rencofilstat, a cyclophilin inhibitor: A phase 2a, multicenter, single‐blind, placebo‐controlled study in F2/F3 NASH

por Harrison, Stephen A., Mayo, Patrick R., Hobbs, Todd M., Canizares, Carlos, Foster, Erin P., Zhao, Caroline, Ure, Daren R., Trepanier, Daniel J., Greytok, Jill A., Foster, Robert T.
Publicado 2022