Dissection of Splicing Regulation at an Endogenous Locus by Zinc-Finger Nuclease-Mediated Gene Editing

por Cristea, Sandra, Gregory, Philip D., Urnov, Fyodor D., Cost, Gregory J.
Publicado 2011

Identification of Chromosome Sequence Motifs That Mediate Meiotic Pairing and Synapsis in C. elegans

por Phillips, Carolyn M., Meng, Xiangdong, Zhang, Lei, Chretien, Jacqueline H., Urnov, Fyodor D., Dernburg, Abby F.
Publicado 2009

Piloting an integrated SARS-CoV-2 testing and data system for outbreak containment among college students: A prospective cohort study

por Packel, Laura, Reingold, Arthur, Hunter, Lauren, Facente, Shelley, Li, Yi, Harte, Anna, Nicolette, Guy, Urnov, Fyodor D., Lu, Michael, Petersen, Maya
Publicado 2021

Disruption of the BCL11A Erythroid Enhancer Reactivates Fetal Hemoglobin in Erythroid Cells of Patients with β-Thalassemia Major

por Psatha, Nikoletta, Reik, Andreas, Phelps, Susan, Zhou, Yuanyue, Dalas, Demetri, Yannaki, Evangelia, Levasseur, Dana N., Urnov, Fyodor D., Holmes, Michael C., Papayannopoulou, Thalia
Publicado 2018

Genetic and molecular identification of three human TPP1 functions in telomerase action: recruitment, activation, and homeostasis set point regulation

por Sexton, Alec N., Regalado, Samuel G., Lai, Christine S., Cost, Gregory J., O’Neil, Colleen M., Urnov, Fyodor D., Gregory, Philip D., Jaenisch, Rudolf, Collins, Kathleen, Hockemeyer, Dirk
Publicado 2014

Mammalian interspecies substitution of immune modulatory alleles by genome editing

por Lillico, Simon G., Proudfoot, Chris, King, Tim J., Tan, Wenfang, Zhang, Lei, Mardjuki, Rachel, Paschon, David E., Rebar, Edward J., Urnov, Fyodor D., Mileham, Alan J., McLaren, David G., Whitelaw, C. Bruce A.
Publicado 2016

Heritable Targeted Gene Disruption in Zebrafish Using Designed Zinc Finger Nucleases

por Doyon, Yannick, McCammon, Jasmine M, Miller, Jeffrey C, Faraji, Farhoud, Ngo, Catherine, Katibah, George E, Amora, Rainier, Hocking, Toby D, Zhang, Lei, Rebar, Edward J, Gregory, Philip D, Urnov, Fyodor D, Amacher, Sharon L
Publicado 2008

Human Intestinal Tissue with Adult Stem Cell Properties Derived from Pluripotent Stem Cells

por Forster, Ryan, Chiba, Kunitoshi, Schaeffer, Lorian, Regalado, Samuel G., Lai, Christine S., Gao, Qing, Kiani, Samira, Farin, Henner F., Clevers, Hans, Cost, Gregory J., Chan, Andy, Rebar, Edward J., Urnov, Fyodor D., Gregory, Philip D., Pachter, Lior, Jaenisch, Rudolf, Hockemeyer, Dirk
Publicado 2014

Human Intestinal Tissue with Adult Stem Cell Properties Derived from Pluripotent Stem Cells

por Forster, Ryan, Chiba, Kunitoshi, Schaeffer, Lorian, Regalado, Samuel G., Lai, Christine S., Gao, Qing, Kiani, Samira, Farin, Henner F., Clevers, Hans, Cost, Gregory J., Chan, Andy, Rebar, Edward J., Urnov, Fyodor D., Gregory, Philip D., Pachter, Lior, Jaenisch, Rudolf, Hockemeyer, Dirk
Publicado 2014

Zinc-finger nuclease-driven targeted integration into mammalian genomes using donors with limited chromosomal homology

por Orlando, Salvatore J., Santiago, Yolanda, DeKelver, Russell C., Freyvert, Yevgeniy, Boydston, Elizabeth A., Moehle, Erica A., Choi, Vivian M., Gopalan, Sunita M., Lou, Jacqueline F., Li, James, Miller, Jeffrey C., Holmes, Michael C., Gregory, Philip D., Urnov, Fyodor D., Cost, Gregory J.
Publicado 2010

Genetic engineering of human ES and iPS cells using TALE nucleases

por Hockemeyer, Dirk, Wang, Haoyi, Kiani, Samira, Lai, Christine S, Gao, Qing, Cassady, John P, Cost, Gregory J, Zhang, Lei, Santiago, Yolanda, Miller, Jeffrey C, Zeitler, Bryan, Cherone, Jennifer M, Meng, Xiangdong, Hinkley, Sarah J, Rebar, Edward J, Gregory, Philip D, Urnov, Fyodor D, Jaenisch, Rudolf
Publicado 2011

Long-Term Engraftment and Fetal Globin Induction upon BCL11A Gene Editing in Bone-Marrow-Derived CD34(+) Hematopoietic Stem and Progenitor Cells

por Chang, Kai-Hsin, Smith, Sarah E., Sullivan, Timothy, Chen, Kai, Zhou, Qianhe, West, Jason A., Liu, Mei, Liu, Yingchun, Vieira, Benjamin F., Sun, Chao, Hong, Vu P., Zhang, Mingxuan, Yang, Xiao, Reik, Andreas, Urnov, Fyodor D., Rebar, Edward J., Holmes, Michael C., Danos, Olivier, Jiang, Haiyan, Tan, Siyuan
Publicado 2017

Translating Dosage Compensation to Trisomy 21

por Jiang, Jun, Jing, Yuanchun, Cost, Gregory J., Chiang, Jen-Chieh, Kolpa, Heather J., Cotton, Allison M., Carone, Dawn M., Carone, Benjamin R., Shivak, David A., Guschin, Dmitry Y., Pearl, Jocelynn R., Rebar, Edward J., Byron, Meg, Gregory, Philip D., Brown, Carolyn J., Urnov, Fyodor D., Hall, Lisa L., Lawrence, Jeanne B.
Publicado 2013

Targeted Gene Addition to a Safe Harbor locus in human CD34(+) Hematopoietic Stem Cells for Correction of X-linked Chronic Granulomatous Disease

por De Ravin, Suk See, Reik, Andreas, Liu, Pei-Qi, Li, Linhong, Wu, Xiaolin, Su, Ling, Raley, Castle, Theobald, Narda, Choi, Uimook, Song, Alexander H., Chan, Andy, Pearl, Jocelynn R., Paschon, David E., Lee, Janet, Newcombe, Hannah, Koontz, Sherry, Sweeney, Colin, Shivak, David A., Zarember, Kol A., Peshwa, Madhusudan V., Gregory, Philip D., Urnov, Fyodor D., Malech, Harry L.
Publicado 2016

IGI-LuNER: single-well multiplexed RT-qPCR test for SARS-CoV-2

por Stahl, Elizabeth C., Tsuchida, Connor A., Hamilton, Jennifer R., Lin-Shiao, Enrique, McDevitt, Shana L., Moehle, Erica A., Witkowsky, Lea B., Tsui, C. Kimberly, Pestal, Kathleen, Gildea, Holly K., McElroy, Matthew, Keller, Amanda, Sylvain, Iman, Williams, Clara, Hirsh, Ariana, Ciling, Alison, Ehrenberg, Alexander J., Urnov, Fyodor D., Ringeisen, Bradley R., Giannikopoulos, Petros, Doudna, Jennifer A.
Publicado 2020

Robotic RNA extraction for SARS-CoV-2 surveillance using saliva samples

por Hamilton, Jennifer R., Stahl, Elizabeth C., Tsuchida, Connor A., Lin-Shiao, Enrique, Tsui, C. Kimberly, Pestal, Kathleen, Gildea, Holly K., Witkowsky, Lea B., Moehle, Erica A., McDevitt, Shana L., McElroy, Matthew, Keller, Amanda, Sylvain, Iman, Hirsh, Ariana, Ciling, Alison, Ehrenberg, Alexander J., Ringeisen, Bradley R., Huberty, Garth, Urnov, Fyodor D., Giannikopoulos, Petros, Doudna, Jennifer A.
Publicado 2021

Robotic RNA extraction for SARS-CoV-2 surveillance using saliva samples

por Hamilton, Jennifer R., Stahl, Elizabeth C., Tsuchida, Connor A., Lin-Shiao, Enrique, Tsui, C. Kimberly, Pestal, Kathleen, Gildea, Holly K., Witkowsky, Lea B., Moehle, Erica A., McDevitt, Shana L., McElroy, Matthew, Keller, Amanda, Sylvain, Iman, Hirsh, Ariana, Ciling, Alison, Ehrenberg, Alexander J., Ringeisen, Bradley R., Huberty, Garth, Urnov, Fyodor D., Giannikopoulos, Petros, Doudna, Jennifer A.
Publicado 2021

Functional footprinting of regulatory DNA

por Vierstra, Jeff, Reik, Andreas, Chang, Kai-Hsin, Stehling-Sun, Sandra, Zhou, Yuan-Yue, Hinkley, Sarah J., Paschon, David E., Zhang, L., Psatha, Nikoletta, Bendana, Yuri R., O'Neill, Colleen M., Song, Alex H., Mich, Andrea, Liu, Pei-Qi, Lee, Gary, Bauer, Daniel E., Holmes, Michael C., Orkin, Stuart H., Papayannopoulou, Thalia, Stamatoyannopoulos, George, Rebar, Edward J., Gregory, Philip D., Urnov, Fyodor D., Stamatoyannopoulos, John A.
Publicado 2015

LuNER: Multiplexed SARS-CoV-2 detection in clinical swab and wastewater samples

por Stahl, Elizabeth C., Gopez, Allan R., Tsuchida, Connor A., Fan, Vinson B., Moehle, Erica A., Witkowsky, Lea B., Hamilton, Jennifer R., Lin-Shiao, Enrique, McElroy, Matthew, McDevitt, Shana L., Ciling, Alison, Tsui, C. Kimberly, Pestal, Kathleen, Gildea, Holly K., Keller, Amanda, Sylvain, Iman A., Williams, Clara, Hirsh, Ariana, Ehrenberg, Alexander J., Kantor, Rose, Metzger, Matthew, Nelson, Kara L., Urnov, Fyodor D., Ringeisen, Bradley R., Giannikopoulos, Petros, Doudna, Jennifer A.
Publicado 2021

Persistent repression of tau in the brain using engineered zinc finger protein transcription factors

por Wegmann, Susanne, DeVos, Sarah L., Zeitler, Bryan, Marlen, Kimberly, Bennett, Rachel E., Perez-Rando, Marta, MacKenzie, Danny, Yu, Qi, Commins, Caitlin, Bannon, Riley N., Corjuc, Bianca T., Chase, Alison, Diez, Lisa, Nguyen, Hoang-Oanh B., Hinkley, Sarah, Zhang, Lei, Goodwin, Alicia, Ledeboer, Annemarie, Lam, Stephen, Ankoudinova, Irina, Tran, Hung, Scarlott, Nicholas, Amora, Rainier, Surosky, Richard, Miller, Jeffrey C., Robbins, Ashley B., Rebar, Edward J., Urnov, Fyodor D., Holmes, Michael C., Pooler, Amy M., Riley, Brigit, Zhang, H. Steve, Hyman, Bradley T.
Publicado 2021