A virus-like particle-based bivalent PCSK9 vaccine lowers LDL-cholesterol levels in non-human primates

por Fowler, Alexandra, Van Rompay, Koen K. A., Sampson, Maureen, Leo, Javier, Watanabe, Jennifer K., Usachenko, Jodie L., Immareddy, Ramya, Lovato, Debbie M., Schiller, John T., Remaley, Alan T., Chackerian, Bryce
Publicado 2023

Evolution of ocular defects in infant macaques following in utero Zika virus infection

por Yiu, Glenn, Thomasy, Sara M., Casanova, M. Isabel, Rusakevich, Alexander, Keesler, Rebekah I., Watanabe, Jennifer, Usachenko, Jodie, Singapuri, Anil, Ball, Erin E., Bliss-Moreau, Eliza, Guo, Wendi, Webster, Helen, Singh, Tulika, Permar, Sallie, Ardeshir, Amir, Coffey, Lark L., Van Rompay, Koen K.A.
Publicado 2020

Two Sides of a Coin: a Zika Virus Mutation Selected in Pregnant Rhesus Macaques Promotes Fetal Infection in Mice but at a Cost of Reduced Fitness in Nonpregnant Macaques and Dimini...

por Lemos, Danilo, Stuart, Jackson B., Louie, William, Singapuri, Anil, Ramírez, Ana L., Watanabe, Jennifer, Usachenko, Jodie, Keesler, Rebekah I., Sanchez-San Martin, Claudia, Li, Tony, Martyn, Calla, Oliveira, Glenn, Saraf, Sharada, Grubaugh, Nathan D., Andersen, Kristian G., Thissen, James, Allen, Jonathan, Borucki, Monica, Tsetsarkin, Konstantin A., Pletnev, Alexander G., Chiu, Charles Y., Van Rompay, Koen K. A., Coffey, Lark L.
Publicado 2020

Monoclonal antibodies protect aged rhesus macaques from SARS-CoV-2-induced immune activation and neuroinflammation

por Verma, Anil, Hawes, Chase E., Lakshmanappa, Yashavanth Shaan, Roh, Jamin W., Schmidt, Brian A., Dutra, Joseph, Louie, William, Liu, Hongwei, Ma, Zhong-Min, Watanabe, Jennifer K., Usachenko, Jodie L., Immareddy, Ramya, Sammak, Rebecca L., Pollard, Rachel, Reader, J. Rachel, Olstad, Katherine J., Coffey, Lark L., Kozlowski, Pamela A., Hartigan-O’Connor, Dennis J., Nussenzweig, Michel, Van Rompay, Koen K.A., Morrison, John H., Iyer, Smita S.
Publicado 2021

A combination of two human monoclonal antibodies limits fetal damage by Zika virus in macaques

por Van Rompay, Koen K. A., Coffey, Lark L., Kapoor, Tania, Gazumyan, Anna, Keesler, Rebekah I., Jurado, Andrea, Peace, Avery, Agudelo, Marianna, Watanabe, Jennifer, Usachenko, Jodie, Singapuri, Anil, Immareddy, Ramya, Ardeshir, Amir, Stuart, Jackson B., Bournazos, Stylianos, Ravetch, Jeffrey V., Balderes, Paul J., Lorenz, Ivo C., Esswein, Shannon R., Keeffe, Jennifer R., Bjorkman, Pamela J., Wang, Qiao, Rice, Charles M., MacDonald, Margaret R., Nussenzweig, Michel C., Robbiani, Davide F.
Publicado 2020

SARS-CoV-2 infection induces robust germinal center CD4 T follicular helper cell responses in rhesus macaques

por Elizaldi, Sonny, Lakshmanappa, Yashavanth Shaan, Roh, Jamin, Schmidt, Brian, Carroll, Timothy, Weaver, Kourtney, Smith, Justin, Deere, Jesse, Dutra, Joseph, Stone, Mars, Franz, Sergej, Sammak, Rebecca, Olstad, Katherine, Reader, J. Rachel, Ma, Zhong-Min, Nguyen, Nancy, Watanabe, Jennifer, Usachenko, Jodie, Immareddy, Ramya, Yee, JoAnn, Weiskopf, Daniela, Sette, Alessandro, Hartigan-O’Connor, Dennis, McSorley, Stephen, Morrison, John, Tran, Nam, Simmons, Graham, Busch, Michael, Kozlowsk, Pamela, van Rompay, Koen, Miller, Christopher, Iyer, Smita
Publicado 2020

Intraamniotic Zika virus inoculation of pregnant rhesus macaques produces fetal neurologic disease

por Coffey, Lark L., Keesler, Rebekah I., Pesavento, Patricia A., Woolard, Kevin, Singapuri, Anil, Watanabe, Jennifer, Cruzen, Christina, Christe, Kari L., Usachenko, Jodie, Yee, JoAnn, Heng, Victoria A., Bliss-Moreau, Eliza, Reader, J. Rachel, von Morgenland, Wilhelm, Gibbons, Anne M., Jackson, Kenneth, Ardeshir, Amir, Heimsath, Holly, Permar, Sallie, Senthamaraikannan, Paranthaman, Presicce, Pietro, Kallapur, Suhas G., Linnen, Jeffrey M., Gao, Kui, Orr, Robert, MacGill, Tracy, McClure, Michelle, McFarland, Richard, Morrison, John H., Van Rompay, Koen K. A.
Publicado 2018

SARS-CoV-2 Infection of Rhesus Macaques Treated Early with Human COVID-19 Convalescent Plasma

por Deere, Jesse D., Carroll, Timothy D., Dutra, Joseph, Fritts, Linda, Sammak, Rebecca Lee, Yee, JoAnn L., Olstad, Katherine J., Reader, J. Rachel, Kistler, Amy, Kamm, Jack, Di Germanio, Clara, Shaan Lakshmanappa, Yashavanth, Elizaldi, Sonny R., Roh, Jamin W., Simmons, Graham, Watanabe, Jennifer, Pollard, Rachel E., Usachenko, Jodie, Immareddy, Ramya, Schmidt, Brian A., O’Connor, Shelby L., DeRisi, Joseph, Busch, Michael P., Iyer, Smita S., Van Rompay, Koen K. A., Hartigan-O’Connor, Dennis J., Miller, Christopher J.
Publicado 2021

Early treatment with a combination of two potent neutralizing antibodies improves clinical outcomes and reduces virus replication and lung inflammation in SARS-CoV-2 infected macaq...

por Van Rompay, Koen K. A., Olstad, Katherine J., Sammak, Rebecca L., Dutra, Joseph, Watanabe, Jennifer K., Usachenko, Jodie L., Immareddy, Ramya, Verma, Anil, Shaan Lakshmanappa, Yashavanth, Schmidt, Brian A., Roh, Jamin W., Elizaldi, Sonny R., Allen, A. Mark, Muecksch, Frauke, Lorenzi, Julio C. C., Lockwood, Sarah, Pollard, Rachel E., Yee, JoAnn L., Nham, Peter B., Ardeshir, Amir, Deere, Jesse D., Patterson, Jean, Dang, Que, Hatziioannou, Theodora, Bieniasz, Paul D., Iyer, Smita S., Hartigan-O’Connor, Dennis J., Nussenzweig, Michel C., Reader, J. Rachel
Publicado 2021

SARS-CoV-2 induces robust germinal center CD4 T follicular helper cell responses in rhesus macaques

por Shaan Lakshmanappa, Yashavanth, Elizaldi, Sonny R., Roh, Jamin W., Schmidt, Brian A., Carroll, Timothy D., Weaver, Kourtney D., Smith, Justin C., Verma, Anil, Deere, Jesse D., Dutra, Joseph, Stone, Mars, Franz, Sergej, Sammak, Rebecca Lee, Olstad, Katherine J., Rachel Reader, J., Ma, Zhong-Min, Nguyen, Nancy K., Watanabe, Jennifer, Usachenko, Jodie, Immareddy, Ramya, Yee, JoAnn L., Weiskopf, Daniela, Sette, Alessandro, Hartigan-O’Connor, Dennis, McSorley, Stephen J., Morrison, John H., Tran, Nam K., Simmons, Graham, Busch, Michael P., Kozlowski, Pamela A., Van Rompay, Koen K. A., Miller, Christopher J., Iyer, Smita S.
Publicado 2021

Early post-infection treatment of SARS-CoV-2 infected macaques with human convalescent plasma with high neutralizing activity reduces lung inflammation

por Van Rompay, Koen K.A., Olstad, Katherine J., Sammak, Rebecca L., Dutra, Joseph, Watanabe, Jennifer K., Usachenko, Jodie L., Immareddy, Ramya, Roh, Jamin W., Verma, Anil, Shaan Lakshmanappa, Yashavanth, Schmidt, Brian A., Di Germanio, Clara, Rizvi, Nabeela, Stone, Mars, Simmons, Graham, Dumont, Larry J., Allen, A. Mark, Lockwood, Sarah, Pollard, Rachel E., de Assis, Rafael Ramiro, Yee, JoAnn L., Nham, Peter B., Ardeshir, Amir, Deere, Jesse D., Patterson, Jean, Jain, Aarti, Felgner, Philip L., Iyer, Smita S., Hartigan-O’Connor, Dennis J., Busch, Michael P., Reader, J. Rachel
Publicado 2021

Early post-infection treatment of SARS-CoV-2 infected macaques with human convalescent plasma with high neutralizing activity had no antiviral effects but moderately reduced lung i...

por Van Rompay, Koen K. A., Olstad, Katherine J., Sammak, Rebecca L., Dutra, Joseph, Watanabe, Jennifer K., Usachenko, Jodie L., Immareddy, Ramya, Roh, Jamin W., Verma, Anil, Shaan Lakshmanappa, Yashavanth, Schmidt, Brian A., Di Germanio, Clara, Rizvi, Nabeela, Liu, Hongwei, Ma, Zhong-Min, Stone, Mars, Simmons, Graham, Dumont, Larry J., Allen, A. Mark, Lockwood, Sarah, Pollard, Rachel E., Ramiro de Assis, Rafael, Yee, JoAnn L., Nham, Peter B., Ardeshir, Amir, Deere, Jesse D., Jain, Aarti, Felgner, Philip L., Coffey, Lark L., Iyer, Smita S., Hartigan-O’Connor, Dennis J., Busch, Michael P., Reader, J. Rachel
Publicado 2022

Infant rhesus macaques immunized against SARS-CoV-2 are protected against heterologous virus challenge one year later

por Milligan, Emma C., Olstad, Katherine, Williams, Caitlin A., Mallory, Michael, Cano, Patricio, Cross, Kaitlyn A., Munt, Jennifer E., Garrido, Carolina, Lindesmith, Lisa, Watanabe, Jennifer, Usachenko, Jodie L., Hopkins, Lincoln, Immareddy, Ramya, Lakshmanappa, Yashavanth Shaan, Elizaldi, Sonny R., Roh, Jamin W., Sammak, Rebecca L., Pollard, Rachel E., Yee, JoAnn L., Herbek, Savannah, Scobey, Trevor, Miehlke, Dieter, Fouda, Genevieve, Ferrari, Guido, Gao, Hongmei, Shen, Xiaoying, Kozlowski, Pamela A., Montefiori, David, Hudgens, Michael G., Edwards, Darin K., Carfi, Andrea, Corbett, Kizzmekia S., Graham, Barney S., Fox, Christopher B., Tomai, Mark, Iyer, Smita S., Baric, Ralph, Reader, Rachel, Dittmer, Dirk P., Van Rompay, Koen K.A., Permar, Sallie R., De Paris, Kristina
Publicado 2022