Targeting GATA4 for cardiac repair

por Välimäki, Mika J., Ruskoaho, Heikki J.
Publicado 2019

Domain-Independent Inhibition of CBP/p300 Attenuates α-Synuclein Aggregation

por Hlushchuk, Irena, Ruskoaho, Heikki, Domanskyi, Andrii, Airavaara, Mikko, Välimäki, Mika J.
Publicado 2021

Nuclear Receptor-Like Structure and Interaction of Congenital Heart Disease-Associated Factors GATA4 and NKX2-5

por Kinnunen, Sini, Välimäki, Mika, Tölli, Marja, Wohlfahrt, Gerd, Darwich, Rami, Komati, Hiba, Nemer, Mona, Ruskoaho, Heikki
Publicado 2015

GATA4-targeted compound exhibits cardioprotective actions against doxorubicin-induced toxicity in vitro and in vivo: establishment of a chronic cardiotoxicity model using human iPS...

por Karhu, S. Tuuli, Kinnunen, Sini M., Tölli, Marja, Välimäki, Mika J., Szabó, Zoltán, Talman, Virpi, Ruskoaho, Heikki
Publicado 2020

GATA-targeted compounds modulate cardiac subtype cell differentiation in dual reporter stem cell line

por Välimäki, Mika J., Leigh, Robert S., Kinnunen, Sini M., March, Alexander R., de Sande, Ana Hernández, Kinnunen, Matias, Varjosalo, Markku, Heinäniemi, Merja, Kaynak, Bogac L., Ruskoaho, Heikki
Publicado 2021

Synthesis, Identification, and Structure–Activity Relationship Analysis of GATA4 and NKX2-5 Protein–Protein Interaction Modulators

por Jumppanen, Mikael, Kinnunen, Sini M., Välimäki, Mika J., Talman, Virpi, Auno, Samuli, Bruun, Tanja, Boije af Gennäs, Gustav, Xhaard, Henri, Aumüller, Ingo B., Ruskoaho, Heikki, Yli-Kauhaluoma, Jari
Publicado 2019

Stem cells are the most sensitive screening tool to identify toxicity of GATA4-targeted novel small-molecule compounds

por Karhu, S. Tuuli, Välimäki, Mika J., Jumppanen, Mikael, Kinnunen, Sini M., Pohjolainen, Lotta, Leigh, Robert S., Auno, Samuli, Földes, Gábor, Boije af Gennäs, Gustav, Yli-Kauhaluoma, Jari, Ruskoaho, Heikki, Talman, Virpi
Publicado 2018

Cardiac Actions of a Small Molecule Inhibitor Targeting GATA4–NKX2-5 Interaction

por Kinnunen, Sini M., Tölli, Marja, Välimäki, Mika J., Gao, Erhe, Szabo, Zoltan, Rysä, Jaana, Ferreira, Mónica P. A., Ohukainen, Pauli, Serpi, Raisa, Correia, Alexandra, Mäkilä, Ermei, Salonen, Jarno, Hirvonen, Jouni, Santos, Hélder A., Ruskoaho, Heikki
Publicado 2018