A Dynamic Core in Human NQO1 Controls the Functional and Stability Effects of Ligand Binding and Their Communication across the Enzyme Dimer

por Vankova, Pavla, Salido, Eduardo, Timson, David J., Man, Petr, Pey, Angel L.
Publicado 2019

Structural basis of heterotetrameric assembly and disease mutations in the human cis-prenyltransferase complex

por Bar-El, Michal Lisnyansky, Vaňková, Pavla, Yeheskel, Adva, Simhaev, Luba, Engel, Hamutal, Man, Petr, Haitin, Yoni, Giladi, Moshe
Publicado 2020

Loss of stability and unfolding cooperativity in hPGK1 upon gradual structural perturbation of its N-terminal domain hydrophobic core

por Pacheco-García, Juan Luis, Loginov, Dmitry S., Naganathan, Athi N., Vankova, Pavla, Cano-Muñoz, Mario, Man, Petr, Pey, Angel L.
Publicado 2022

Structural basis for long-chain isoprenoid synthesis by cis-prenyltransferases

por Giladi, Moshe, Lisnyansky Bar-El, Michal, Vaňková, Pavla, Ferofontov, Alisa, Melvin, Emelia, Alkaderi, Suha, Kavan, Daniel, Redko, Boris, Haimov, Elvira, Wiener, Reuven, Man, Petr, Haitin, Yoni
Publicado 2022

Allosteric Communication in the Multifunctional and Redox NQO1 Protein Studied by Cavity-Making Mutations

por Pacheco-Garcia, Juan Luis, Loginov, Dmitry S., Anoz-Carbonell, Ernesto, Vankova, Pavla, Palomino-Morales, Rogelio, Salido, Eduardo, Man, Petr, Medina, Milagros, Naganathan, Athi N., Pey, Angel L.
Publicado 2022

Structural basis of the pleiotropic and specific phenotypic consequences of missense mutations in the multifunctional NAD(P)H:quinone oxidoreductase 1 and their pharmacological res...

por Pacheco-Garcia, Juan Luis, Anoz-Carbonell, Ernesto, Vankova, Pavla, Kannan, Adithi, Palomino-Morales, Rogelio, Mesa-Torres, Noel, Salido, Eduardo, Man, Petr, Medina, Milagros, Naganathan, Athi N., Pey, Angel L.
Publicado 2021