The Use of Mouse Models for Understanding the Biology of Down Syndrome and Aging

por Vacano, Guido N., Duval, Nathan, Patterson, David
Publicado 2012

Rapamycin Treatment Ameliorates Age-Related Accumulation of Toxic Metabolic Intermediates in Brains of the Ts65Dn Mouse Model of Down Syndrome and Aging

por Duval, Nathan, Vacano, Guido N., Patterson, David
Publicado 2018

The CRISPR-Cas9 crADSL HeLa transcriptome: A first step in establishing a model for ADSL deficiency and SAICAR accumulation

por Mazzarino, Randall C., Baresova, Veronika, Zikánová, Marie, Duval, Nathan, Wilkinson, Terry G., Patterson, David, Vacano, Guido N.
Publicado 2019

The CRISPR-Cas9 crATIC HeLa transcriptome: Characterization of a novel cellular model of ATIC deficiency and ZMP accumulation

por Mazzarino, Randall C., Baresova, Veronika, Zikánová, Marie, Duval, Nathan, Wilkinson, Terry G., Patterson, David, Vacano, Guido N.
Publicado 2020

Transcriptome and metabolome analysis of crGART, a novel cell model of de novo purine synthesis deficiency: Alterations in CD36 expression and activity

por Mazzarino, Randall C., Baresova, Veronika, Zikánová, Marie, Duval, Nathan, Wilkinson, Terry G., Patterson, David, Vacano, Guido N.
Publicado 2021

Brain Phenotype of Transgenic Mice Overexpressing Cystathionine β-Synthase

por Régnier, Vinciane, Billard, Jean-Marie, Gupta, Sapna, Potier, Brigitte, Woerner, Stéphanie, Paly, Evelyne, Ledru, Aurélie, David, Sabrina, Luilier, Sabrina, Bizot, Jean-Charles, Vacano, Guido, Kraus, Jan P., Patterson, David, Kruger, Warren D., Delabar, Jean M., London, Jaqueline
Publicado 2012

Reduced purine biosynthesis in humans after their divergence from Neandertals

por Stepanova, Vita, Moczulska, Kaja Ewa, Vacano, Guido N, Kurochkin, Ilia, Ju, Xiangchun, Riesenberg, Stephan, Macak, Dominik, Maricic, Tomislav, Dombrowski, Linda, Schörnig, Maria, Anastassiadis, Konstantinos, Baker, Oliver, Naumann, Ronald, Khrameeva, Ekaterina, Vanushkina, Anna, Stekolshchikova, Elena, Egorova, Alina, Tkachev, Anna, Mazzarino, Randall, Duval, Nathan, Zubkov, Dmitri, Giavalisco, Patrick, Wilkinson, Terry G, Patterson, David, Khaitovich, Philipp, Pääbo, Svante
Publicado 2021