PI3Kβ downstream of GPCRs – crucial partners in oncogenesis

por Dbouk, Hashem A., Vadas, Oscar, Williams, Roger L., Backer, Jonathan M.
Publicado 2012

Auxiliary domains of the HrpB bacterial DExH-box helicase shape its RNA preferences

por Hausmann, Stéphane, Geiser, Johan, Vadas, Oscar, Ducret, Verena, Perron, Karl, Valentini, Martina
Publicado 2020

Pantothenate biosynthesis is critical for chronic infection by the neurotropic parasite Toxoplasma gondii

por Lunghi, Matteo, Kloehn, Joachim, Krishnan, Aarti, Varesio, Emmanuel, Vadas, Oscar, Soldati-Favre, Dominique
Publicado 2022

Dynamics of the Phosphoinositide 3-Kinase p110δ Interaction with p85α and Membranes Reveals Aspects of Regulation Distinct from p110α

por Burke, John E., Vadas, Oscar, Berndt, Alex, Finegan, Tara, Perisic, Olga, Williams, Roger L.
Publicado 2011

SUV39 SET domains mediate crosstalk of heterochromatic histone marks

por Stirpe, Alessandro, Guidotti, Nora, Northall, Sarah J, Kilic, Sinan, Hainard, Alexandre, Vadas, Oscar, Fierz, Beat, Schalch, Thomas
Publicado 2021

Structure of Lipid Kinase p110β/p85β Elucidates an Unusual SH2-Domain-Mediated Inhibitory Mechanism

por Zhang, Xuxiao, Vadas, Oscar, Perisic, Olga, Anderson, Karen E., Clark, Jonathan, Hawkins, Phillip T., Stephens, Len R., Williams, Roger L.
Publicado 2011

Identification of immunodominant linear epitopes from SARS-CoV-2 patient plasma

por Farrera-Soler, Lluc, Daguer, Jean-Pierre, Barluenga, Sofia, Vadas, Oscar, Cohen, Patrick, Pagano, Sabrina, Yerly, Sabine, Kaiser, Laurent, Vuilleumier, Nicolas, Winssinger, Nicolas
Publicado 2020

Naturally acquired blocking human monoclonal antibodies to Plasmodiumvivax reticulocyte binding protein 2b

por Chan, Li-Jin, Gandhirajan, Anugraha, Carias, Lenore L., Dietrich, Melanie H., Vadas, Oscar, Visentin, Remy, França, Camila T., Menant, Sebastien, Soldati-Favre, Dominique, Mueller, Ivo, King, Christopher L., Tham, Wai-Hong
Publicado 2021

Structural insights into an atypical secretory pathway kinase crucial for Toxoplasma gondii invasion

por Lentini, Gaëlle, Ben Chaabene, Rouaa, Vadas, Oscar, Ramakrishnan, Chandra, Mukherjee, Budhaditya, Mehta, Ved, Lunghi, Matteo, Grossmann, Jonas, Maco, Bohumil, Visentin, Rémy, Hehl, Adrian B., Korkhov, Volodymyr M., Soldati-Favre, Dominique
Publicado 2021

Structural basis of phosphatidylinositol 3-kinase C2α function

por Lo, Wen-Ting, Zhang, Yingyi, Vadas, Oscar, Roske, Yvette, Gulluni, Federico, De Santis, Maria Chiara, Zagar, Andreja Vujicic, Stephanowitz, Heike, Hirsch, Emilio, Liu, Fan, Daumke, Oliver, Kudryashev, Misha, Haucke, Volker
Publicado 2022

Structure of the phosphoinositide 3-kinase (PI3K) p110γ-p101 complex reveals molecular mechanism of GPCR activation

por Rathinaswamy, Manoj K., Dalwadi, Udit, Fleming, Kaelin D., Adams, Carson, Stariha, Jordan T. B., Pardon, Els, Baek, Minkyung, Vadas, Oscar, DiMaio, Frank, Steyaert, Jan, Hansen, Scott D., Yip, Calvin K., Burke, John E.
Publicado 2021

Structural and regulatory insights into the glideosome-associated connector from Toxoplasma gondii

por Kumar, Amit, Vadas, Oscar, Dos Santos Pacheco, Nicolas, Zhang, Xu, Chao, Kin, Darvill, Nicolas, Rasmussen, Helena Ø, Xu, Yingqi, Lin, Gloria Meng-Hsuan, Stylianou, Fisentzos A, Pedersen, Jan Skov, Rouse, Sarah L, Morgan, Marc L, Soldati-Favre, Dominique, Matthews, Stephen
Publicado 2023

Inactivation mechanisms of influenza A virus under pH conditions encountered in aerosol particles as revealed by whole-virus HDX-MS

por David, Shannon C., Vadas, Oscar, Glas, Irina, Schaub, Aline, Luo, Beiping, D'angelo, Giovanni, Montoya, Jonathan Paz, Bluvshtein, Nir, Hugentobler, Walter, Klein, Liviana K., Motos, Ghislain, Pohl, Marie, Violaki, Kalliopi, Nenes, Athanasios, Krieger, Ulrich K., Stertz, Silke, Peter, Thomas, Kohn, Tamar
Publicado 2023