Reflections on an inflection: From virology to parasitology guided by POLARIS

por Vaidya, Akhil B.
Publicado 2018

Dramatic Consequences of Reducing Erythrocyte Membrane Cholesterol on Plasmodium falciparum

por Ahiya, Avantika I., Bhatnagar, Suyash, Morrisey, Joanne M., Beck, Josh R., Vaidya, Akhil B.
Publicado 2022

Remarkable stability in patterns of blood-stage gene expression during episodes of non-lethal Plasmodium yoelii malaria

por Cernetich-Ott, Amy, Daly, Thomas M, Vaidya, Akhil B, Bergman, Lawrence W, Burns, James M
Publicado 2012

Transcriptional changes in Plasmodium falciparum upon conditional knock down of mitochondrial ribosomal proteins RSM22 and L23

por Dass, Swati, Mather, Michael W., Morrisey, Joanne M., Ling, Liqin, Vaidya, Akhil B., Ke, Hangjun
Publicado 2022

Characterization of a Plasmodium falciparum Orthologue of the Yeast Ubiquinone-Binding Protein, Coq10p

por Jenkins, Bethany J., Daly, Thomas M., Morrisey, Joanne M., Mather, Michael W., Vaidya, Akhil B., Bergman, Lawrence W.
Publicado 2016

Na(+) Influx Induced by New Antimalarials Causes Rapid Alterations in the Cholesterol Content and Morphology of Plasmodium falciparum

por Das, Sudipta, Bhatanagar, Suyash, Morrisey, Joanne M., Daly, Thomas M., Burns, James M., Coppens, Isabelle, Vaidya, Akhil B.
Publicado 2016

Metabolic adjustments of blood-stage Plasmodium falciparum in response to sublethal pyrazoleamide exposure

por Tewari, Shivendra G., Kwan, Bobby, Elahi, Rubayet, Rajaram, Krithika, Reifman, Jaques, Prigge, Sean T., Vaidya, Akhil B., Wallqvist, Anders
Publicado 2022

Antiparasitic and disease-modifying activity of Nyctanthes arbor-tristis Linn. in malaria: An exploratory clinical study

por Godse, Chhaya S., Tathed, Prakash S., Talwalkar, Sameer S., Vaidya, Rama A., Amonkar, Ashok J., Vaidya, Akhil B., Vaidya, Ashok D.B.
Publicado 2016

Branched Tricarboxylic Acid Metabolism in Plasmodium falciparum

por Olszewski, Kellen L., Mather, Michael W., Morrisey, Joanne M., Garcia, Benjamin A., Vaidya, Akhil B., Rabinowitz, Joshua D., Llinás, Manuel
Publicado 2010

Metabolic responses in blood-stage malaria parasites associated with increased and decreased sensitivity to PfATP4 inhibitors

por Tewari, Shivendra G., Elahi, Rubayet, Kwan, Bobby, Rajaram, Krithika, Bhatnagar, Suyash, Reifman, Jaques, Prigge, Sean T., Vaidya, Akhil B., Wallqvist, Anders
Publicado 2023

Highly Divergent Mitochondrial ATP Synthase Complexes in Tetrahymena thermophila

por Balabaskaran Nina, Praveen, Dudkina, Natalya V., Kane, Lesley A., van Eyk, Jennifer E., Boekema, Egbert J., Mather, Michael W., Vaidya, Akhil B.
Publicado 2010

Mitochondrial type II NADH dehydrogenase of Plasmodium falciparum (PfNDH2) is dispensable in the asexual blood stages

por Ke, Hangjun, Ganesan, Suresh M., Dass, Swati, Morrisey, Joanne M., Pou, Sovitj, Nilsen, Aaron, Riscoe, Michael K., Mather, Michael W., Vaidya, Akhil B.
Publicado 2019

Mitochondrially targeted proximity biotinylation and proteomic analysis in Plasmodium falciparum

por Lamb, Ian M., Rios, Kelly T., Shukla, Anurag, Ahiya, Avantika I., Morrisey, Joanne, Mell, Joshua C., Lindner, Scott E., Mather, Michael W., Vaidya, Akhil B.
Publicado 2022

Plasmodium Niemann-Pick type C1-related protein is a druggable target required for parasite membrane homeostasis

por Istvan, Eva S, Das, Sudipta, Bhatnagar, Suyash, Beck, Josh R, Owen, Edward, Llinas, Manuel, Ganesan, Suresh M, Niles, Jacquin C, Winzeler, Elizabeth, Vaidya, Akhil B, Goldberg, Daniel E
Publicado 2019

A Chemical Genomic Analysis of Decoquinate, a Plasmodium falciparum Cytochrome b Inhibitor

por Nam, Tae-gyu, McNamara, Case W., Bopp, Selina, Dharia, Neekesh V., Meister, Stephan, Bonamy, Ghislain M. C., Plouffe, David M., Kato, Nobutaka, McCormack, Susan, Bursulaya, Badry, Ke, Hangjun, Vaidya, Akhil B., Schultz, Peter G., Winzeler, Elizabeth A.
Publicado 2011

Functional Profiling of a Plasmodium Genome Reveals an Abundance of Essential Genes

por Bushell, Ellen, Gomes, Ana Rita, Sanderson, Theo, Anar, Burcu, Girling, Gareth, Herd, Colin, Metcalf, Tom, Modrzynska, Katarzyna, Schwach, Frank, Martin, Rowena E., Mather, Michael W., McFadden, Geoffrey I., Parts, Leopold, Rutledge, Gavin G., Vaidya, Akhil B., Wengelnik, Kai, Rayner, Julian C., Billker, Oliver
Publicado 2017

Discovery, Synthesis, and Optimization of Antimalarial 4(1H)-Quinolone-3-Diarylethers

por Nilsen, Aaron, Miley, Galen P., Forquer, Isaac P., Mather, Michael W., Katneni, Kasiram, Li, Yuexin, Pou, Sovitj, Pershing, April M., Stickles, Allison M., Ryan, Eileen, Kelly, Jane Xu, Doggett, J. Stone, White, Karen L., Hinrichs, David J., Winter, Rolf W., Charman, Susan A., Zakharov, Lev N., Bathurst, Ian, Burrows, Jeremy N., Vaidya, Akhil B., Riscoe, Michael K.
Publicado 2014

Comparative genomics of the pathogenic ciliate Ichthyophthirius multifiliis, its free-living relatives and a host species provide insights into adoption of a parasitic lifestyle an...

por Coyne, Robert S, Hannick, Linda, Shanmugam, Dhanasekaran, Hostetler, Jessica B, Brami, Daniel, Joardar, Vinita S, Johnson, Justin, Radune, Diana, Singh, Irtisha, Badger, Jonathan H, Kumar, Ujjwal, Saier, Milton, Wang, Yufeng, Cai, Hong, Gu, Jianying, Mather, Michael W, Vaidya, Akhil B, Wilkes, David E, Rajagopalan, Vidyalakshmi, Asai, David J, Pearson, Chad G, Findly, Robert C, Dickerson, Harry W, Wu, Martin, Martens, Cindy, Van de Peer, Yves, Roos, David S, Cassidy-Hanley, Donna M, Clark, Theodore G
Publicado 2011

Pyrazoleamide compounds are potent antimalarials that target Na(+) homeostasis in intraerythrocytic Plasmodium falciparum

por Vaidya, Akhil B., Morrisey, Joanne M., Zhang, Zhongsheng, Das, Sudipta, Daly, Thomas M., Otto, Thomas D., Spillman, Natalie J., Wyvratt, Matthew, Siegl, Peter, Marfurt, Jutta, Wirjanata, Grennady, Sebayang, Boni F., Price, Ric N., Chatterjee, Arnab, Nagle, Advait, Stasiak, Marcin, Charman, Susan A., Angulo-Barturen, Iñigo, Ferrer, Santiago, Belén Jiménez-Díaz, María, Martínez, María Santos, Gamo, Francisco Javier, Avery, Vicky M., Ruecker, Andrea, Delves, Michael, Kirk, Kiaran, Berriman, Matthew, Kortagere, Sandhya, Burrows, Jeremy, Fan, Erkang, Bergman, Lawrence W.
Publicado 2014