Biological specificity of CDK4/6 inhibitors: dose response relationship, in vivo signaling, and composite response signature

por Knudsen, Erik S., Hutcheson, Jack, Vail, Paris, Witkiewicz, Agnieszka K.
Publicado 2017

Interrogating Mutant Allele Expression via Customized Reference Genomes to Define Influential Cancer Mutations

por Grant, Adam D., Vail, Paris, Padi, Megha, Witkiewicz, Agnieszka K., Knudsen, Erik S.
Publicado 2019

Pancreatic cancer cell lines as patient-derived avatars: genetic characterisation and functional utility

por Knudsen, Erik S, Balaji, Uthra, Mannakee, Brian, Vail, Paris, Eslinger, Cody, Moxom, Christopher, Mansour, John, Witkiewicz, Agnieszka K
Publicado 2018

Composite Analysis of Immunological and Metabolic Markers Defines Novel Subtypes of Triple Negative Breast Cancer

por Adams, Thomas A., Vail, Paris J., Ruiz, Amanda, Mollaee, Mehri, McCue, Peter A., Knudsen, Erik S., Witkiewicz, Agnieszka K.
Publicado 2017

A Phase I Study of Ribociclib Plus Everolimus in Patients with Metastatic Pancreatic Adenocarcinoma Refractory to Chemotherapy

por Weinberg, Benjamin A., Wang, Hongkun, Witkiewicz, Agnieszka K., Marshall, John L., He, Aiwu R., Vail, Paris, Knudsen, Erik S., Pishvaian, Michael J.
Publicado 2020

Cell cycle plasticity driven by MTOR signaling: Integral resistance to CDK4/6 inhibition in patient-derived models of pancreatic cancer

por Knudsen, Erik S., Kumarasamy, Vishnu, Ruiz, Amanda, Sivinski, Jared, Chung, Sejin, Grant, Adam, Vail, Paris, Chauhan, Shailender S., Jie, Tun, Riall, Taylor S., Witkiewicz, Agnieszka K.
Publicado 2019

Comparison of locus-specific databases for BRCA1 and BRCA2 variants reveals disparity in variant classification within and among databases

por Vail, Paris J., Morris, Brian, van Kan, Aric, Burdett, Brianna C., Moyes, Kelsey, Theisen, Aaron, Kerr, Iain D., Wenstrup, Richard J., Eggington, Julie M.
Publicado 2015

CDK/cyclin dependencies define extreme cancer cell-cycle heterogeneity and collateral vulnerabilities

por Knudsen, Erik S., Kumarasamy, Vishnu, Nambiar, Ram, Pearson, Joel D., Vail, Paris, Rosenheck, Hanna, Wang, Jianxin, Eng, Kevin, Bremner, Rod, Schramek, Daniel, Rubin, Seth M., Welm, Alana L., Witkiewicz, Agnieszka K.
Publicado 2022

Assessment of in silico protein sequence analysis in the clinical classification of variants in cancer risk genes

por Kerr, Iain D., Cox, Hannah C., Moyes, Kelsey, Evans, Brent, Burdett, Brianna C., van Kan, Aric, McElroy, Heather, Vail, Paris J., Brown, Krystal L., Sumampong, Dechie B., Monteferrante, Nicholas J., Hardman, Kennedy L., Theisen, Aaron, Mundt, Erin, Wenstrup, Richard J., Eggington, Julie M.
Publicado 2017