Glycan Array Evaluation of Synthetic Epitopes between the Capsular Polysaccharides from Streptococcus pneumoniae 19F and 19A

por Morelli, Laura, Lay, Luigi, Santana-Mederos, Darielys, Valdes-Balbin, Yury, Verez Bencomo, Vicente, van Diepen, Angela, Hokke, Cornelis H., Chiodo, Fabrizio, Compostella, Federica
Publicado 2021

Synthetic, Zwitterionic Sp1 Oligosaccharides Adopt a Helical Structure Crucial for Antibody Interaction

por Zhang, Qingju, Gimeno, Ana, Santana, Darielys, Wang, Zhen, Valdés-Balbin, Yury, Rodríguez-Noda, Laura M., Hansen, Thomas, Kong, Li, Shen, Mengjie, Overkleeft, Herman S., Vérez-Bencomo, Vicente, van der Marel, Gijsbert A., Jiménez-Barbero, Jesús, Chiodo, Fabrizio, Codée, Jeroen D. C.
Publicado 2019

Molecular Aspects Concerning the Use of the SARS-CoV-2 Receptor Binding Domain as a Target for Preventive Vaccines

por Valdes-Balbin, Yury, Santana-Mederos, Darielys, Paquet, Françoise, Fernandez, Sonsire, Climent, Yanet, Chiodo, Fabrizio, Rodríguez, Laura, Sanchez Ramirez, Belinda, Leon, Kalet, Hernandez, Tays, Castellanos-Serra, Lila, Garrido, Raine, Chen, Guang-Wu, Garcia-Rivera, Dagmar, Rivera, Daniel G., Verez-Bencomo, Vicente
Publicado 2021

Potency, toxicity and protection evaluation of PastoCoAd candidate vaccines: Novel preclinical mix and match rAd5 S, rAd5 RBD-N and SOBERANA dimeric-RBD protein

por Pouriayevali, Mohammad Hassan, Teimoori, Ali, Esmaeili, Saber, Abdoli, Asghar, Doroud, Delaram, Salehi-Vaziri, Mostafa, Shahali, Maryam, Kadkhodazadeh, Maryam, Sabouni, Talieh, Khosravi, Mohammad Ali, Panahi, Mohammad, Khoshroo, Fereidoon, Bahmanjeh, Anahita, Valdes-Balbin, Yury, Garcia-Rivera, Dagmar, Verez-Bencomo, Vicente, Biglari, Alireza, Baesi, Kazem
Publicado 2022

Corrigendum to “Potency, toxicity and protection evaluation of PastoCoAd candidate vaccines: Novel preclinical mix and match rAd5 S, rAd5 RBD-N and SOBERANA dimeric-RBD protein” [V...

por Pouriayevali, Mohammad Hassan, Teimoori, Ali, Esmaeili, Saber, Abdoli, Asghar, Doroud, Delaram, Salehi-Vaziri, Mostafa, Shahali, Maryam, Kadkhodazadeh, Maryam, Sabouni, Talieh, Ali Khosravi, Mohammad, Panahi, Mohammad, Khoshroo, Fereidoon, Bahmanjeh, Anahita, Valdes-Balbin, Yury, Garcia-Rivera, Dagmar, Verez-Bencomo, Vicente, Biglari, Alireza, Baesi, Kazem
Publicado 2022

Comparative Immune Response after Vaccination with SOBERANA(®) 02 and SOBERANA(®) plus Heterologous Scheme and Natural Infection in Young Children

por Pérez-Nicado, Rocmira, Massa, Chiara, Rodríguez-Noda, Laura Marta, Müller, Anja, Puga-Gómez, Rinaldo, Ricardo-Delgado, Yariset, Paredes-Moreno, Beatriz, Rodríguez-González, Meiby, García-Ferrer, Marylé, Palmero-Álvarez, Ilianet, Garcés-Hechavarría, Aniurka, Rivera, Daniel G., Valdés-Balbín, Yury, Vérez-Bencomo, Vicente, García-Rivera, Dagmar, Seliger, Barbara
Publicado 2023

In-solution buffer-free digestion allows full-sequence coverage and complete characterization of post-translational modifications of the receptor-binding domain of SARS-CoV-2 in a...

por Espinosa, Luis Ariel, Ramos, Yassel, Andújar, Ivan, Torres, Enso Onill, Cabrera, Gleysin, Martín, Alejandro, Roche, Diamilé, Chinea, Glay, Becquet, Mónica, González, Isabel, Canaán-Haden, Camila, Nelson, Elías, Rojas, Gertrudis, Pérez-Massón, Beatriz, Pérez-Martínez, Dayana, Boggiano, Tamy, Palacio, Julio, Lozada Chang, Sum Lai, Hernández, Lourdes, de la Luz Hernández, Kathya Rashida, Markku, Saloheimo, Vitikainen, Marika, Valdés-Balbín, Yury, Santana-Medero, Darielys, Rivera, Daniel G., Vérez-Bencomo, Vicente, Emalfarb, Mark, Tchelet, Ronen, Guillén, Gerardo, Limonta, Miladys, Pimentel, Eulogio, Ayala, Marta, Besada, Vladimir, González, Luis Javier
Publicado 2021

A randomized, double-blind phase I clinical trial of two recombinant dimeric RBD COVID-19 vaccine candidates: Safety, reactogenicity and immunogenicity

por Pérez-Rodríguez, Sonia, de la Caridad Rodríguez-González, Meiby, Ochoa-Azze, Rolando, Climent-Ruiz, Yanet, Alberto González-Delgado, Carlos, Paredes-Moreno, Beatriz, Valenzuela-Silva, Carmen, Rodríguez-Noda, Laura, Perez-Nicado, Rocmira, González-Mugica, Raúl, Martínez-Pérez, Marisel, Sánchez-Ramírez, Belinda, Hernández-García, Tays, Díaz-Machado, Alina, Tamayo-Rodríguez, Maura, Martín-Trujillo, Alis, Rubino-Moreno, Jorman, Suárez-Batista, Anamary, Dubed-Echevarría, Marta, Teresa Pérez-Guevara, María, Amoroto-Roig, Mayté, Chappi-Estévez, Yanet, Bergado-Báez, Gretchen, Pi-Estopiñán, Franciscary, Chen, Guang-Wu, Valdés-Balbín, Yury, García-Rivera, Dagmar, Verez-Bencomo, Vicente
Publicado 2022

Safety and immunogenicity of the FINLAY-FR-1A vaccine in COVID-19 convalescent participants: an open-label phase 2a and double-blind, randomised, placebo-controlled, phase 2b, seam...

por Ochoa-Azze, Rolando, Chang-Monteagudo, Arturo, Climent-Ruiz, Yanet, Macías-Abraham, Consuelo, Valenzuela-Silva, Carmen, de los Ángeles García-García, María, Jerez-Barceló, Yanet, Triana-Marrero, Yenisey, Ruiz-Villegas, Laura, Dairon Rodríguez-Prieto, Luis, Guerra-Chaviano, Pedro Pablo, Sánchez-Ramírez, Belinda, Hernández-García, Tays, Orosa-Vázquez, Ivette, Díaz-Hernández, Marianniz, Chiodo, Fabrizio, Calcagno, Andrea, Ghisetti, Valeria, Rodríguez-Acosta, Mireida, Noa-Romero, Enrique, Enríquez-Puertas, Juliet, Ortega-León, Darién, Valdivia-Álvarez, Irinia, Delahanty-Fernández, Aurora, Palenzuela-Díaz, Ariel, Rodríguez-Noda, Laura, González-Mugica, Raúl, Valdés-Balbín, Yury, García-Rivera, Dagmar, Verez-Bencomo, Vicente
Publicado 2022

A single dose of SARS-CoV-2 FINLAY-FR-1A vaccine enhances neutralization response in COVID-19 convalescents, with a very good safety profile: An open-label phase 1 clinical trial

por Chang-Monteagudo, Arturo, Ochoa-Azze, Rolando, Climent-Ruiz, Yanet, Macías-Abraham, Consuelo, Rodríguez-Noda, Laura, Valenzuela-Silva, Carmen, Sánchez-Ramírez, Belinda, Perez-Nicado, Rocmira, Hernández-García, Tays, Orosa-Vázquez, Ivette, Díaz-Hernández, Marianniz, García-García, María de los Ángeles, Jerez-Barceló, Yanet, Triana-Marrero, Yenisey, Ruiz-Villegas, Laura, Rodríguez-Prieto, Luis Dairon, Puga-Gómez, Rinaldo, Guerra-Chaviano, Pedro Pablo, Zúñiga-Rosales, Yaíma, Marcheco-Teruel, Beatriz, Rodríguez-Acosta, Mireida, Noa-Romero, Enrique, Enríquez-Puertas, Juliet, Porto-González, Delia, Fernández-Medina, Olivia, Valdés-Zayas, Anet, Chen, Guang-Wu, Herrera-Martínez, Luís, Valdés-Balbín, Yury, García-Rivera, Dagmar, Verez-Bencomo, Vicente
Publicado 2021

Safety and immunogenicity of anti-SARS-CoV-2 heterologous scheme with SOBERANA 02 and SOBERANA Plus vaccines: Phase IIb clinical trial in adults

por Toledo-Romani, María Eugenia, García-Carmenate, Mayra, Verdecia-Sánchez, Leslyhana, Pérez-Rodríguez, Suzel, Rodriguez-González, Meybis, Valenzuela-Silva, Carmen, Paredes-Moreno, Beatriz, Sanchez-Ramirez, Belinda, González-Mugica, Raúl, Hernández-Garcia, Tays, Orosa-Vázquez, Ivette, Díaz-Hernández, Marianniz, Pérez-Guevara, María Teresa, Enriquez-Puertas, Juliet, Noa-Romero, Enrique, Palenzuela-Diaz, Ariel, Baro-Roman, Gerardo, Mendoza-Hernández, Ivis, Muñoz, Yaima, Gómez-Maceo, Yanet, Santos-Vega, Bertha Leysi, Fernandez-Castillo, Sonsire, Climent-Ruiz, Yanet, Rodríguez-Noda, Laura, Santana-Mederos, Darielys, García-Vega, Yanelda, Chen, Guang-Wu, Doroud, Delaram, Biglari, Alireza, Boggiano-Ayo, Tammy, Valdés-Balbín, Yury, Rivera, Daniel G., García-Rivera, Dagmar, Vérez-Bencomo, Vicente
Publicado 2022

A COVID-19 vaccine candidate composed of the SARS-CoV-2 RBD dimer and Neisseria meningitidis outer membrane vesicles

por Santana-Mederos, Darielys, Perez-Nicado, Rocmira, Climent, Yanet, Rodriguez, Laura, Ramirez, Belinda Sanchez, Perez-Rodriguez, Sonia, Rodriguez, Meybi, Labrada, Claudia, Hernandez, Tays, Diaz, Marianniz, Orosa, Ivette, Ramirez, Ubel, Oliva, Reynaldo, Garrido, Raine, Cardoso, Felix, Landys, Mario, Martinez, Roselyn, Gonzalez, Humberto, Hernandez, Tamara, Ochoa-Azze, Rolando, Perez, Jose L., Enriquez, Juliet, Gonzalez, Nibaldo, Infante, Yenicet, Espinosa, Luis A., Ramos, Yassel, González, Luis Javier, Valenzuela, Carmen, Casadesus, Ana Victoria, Fernandez, Briandy, Rojas, Gertrudis, Pérez-Massón, Beatriz, Tundidor, Yaima, Bermudez, Ernesto, Plasencia, Claudia A., Boggiano, Tammy, Ojito, Eduardo, Chiodo, Fabrizio, Fernandez, Sonsire, Paquet, Françoise, Fang, Cheng, Chen, Guang-Wu, Rivera, Daniel G., Valdes-Balbin, Yury, Garcia-Rivera, Dagmar, Verez Bencomo, Vicente
Publicado 2021

Open-label phase I/II clinical trial of SARS-CoV-2 receptor binding domain-tetanus toxoid conjugate vaccine (FINLAY-FR-2) in combination with receptor binding domain-protein vaccin...

por Puga-Gómez, Rinaldo, Ricardo-Delgado, Yariset, Rojas-Iriarte, Chaumey, Céspedes-Henriquez, Leyanis, Piedra-Bello, Misleidys, Vega-Mendoza, Dania, Pérez, Noelvia Pestana, Paredes-Moreno, Beatriz, Rodríguez-González, Meiby, Valenzuela-Silva, Carmen, Sánchez-Ramírez, Belinda, Rodríguez-Noda, Laura, Pérez-Nicado, Rocmira, González-Mugica, Raul, Hernández-García, Tays, Fundora-Barrios, Talía, Echevarría, Martha Dubet, Enriquez-Puertas, Juliet María, Infante-Hernández, Yenicet, Palenzuela-Díaz, Ariel, Gato-Orozco, Evelyn, Chappi-Estévez, Yanet, Francisco-Pérez, Julio Cesar, Suarez-Martinez, Miladi, Castillo-Quintana, Ismavy C., Fernandez-Castillo, Sonsire, Climent-Ruiz, Yanet, Santana-Mederos, Darielys, García-Vega, Yanelda, Toledo-Romani, María Eugenia, Doroud, Delaram, Biglari, Alireza, Valdés-Balbín, Yury, García-Rivera, Dagmar, Vérez-Bencomo, Vicente
Publicado 2023

Safety and efficacy of the two doses conjugated protein-based SOBERANA-02 COVID-19 vaccine and of a heterologous three-dose combination with SOBERANA-Plus: a double-blind, randomis...

por Toledo-Romaní, María Eugenia, García-Carmenate, Mayra, Valenzuela-Silva, Carmen, Baldoquín-Rodríguez, Waldemar, Martínez-Pérez, Marisel, Rodríguez-González, Meiby, Paredes-Moreno, Beatriz, Mendoza-Hernández, Ivis, González-Mujica Romero, Raúl, Samón-Tabio, Oscar, Velazco-Villares, Pablo, Bacallao-Castillo, Juan Pablo, Licea-Martín, Ernesto, Rodríguez-Ortega, Misladys, Herrera-Marrero, Nuris, Caballero-González, Esperanza, Egües-Torres, Liudmila, Duartes-González, Reinaldo, García-Blanco, Serguey, Pérez-Cabrera, Suzette, Huete-Ferreira, Santos, Idalmis-Cisnero, Kirenia, Fonte-Galindo, Omayda, Meliá-Pérez, Dania, Rojas-Remedios, Ivonne, Doroud, Delaram, Gouya, Mohammad Mehdi, Biglari, Alireza, Fernández-Castillo, Sonsire, Climent-Ruiz, Yanet, Valdes-Balbín, Yury, García-Rivera, Dagmar, Van der Stuyft, Patrick, Verez-Bencomo, Vicente
Publicado 2022

Safety and immunogenicity of anti-SARS CoV-2 vaccine SOBERANA 02 in homologous or heterologous scheme: Open label phase I and phase IIa clinical trials

por Eugenia-Toledo-Romaní, María, Verdecia-Sánchez, Leslyhana, Rodríguez-González, Meiby, Rodríguez-Noda, Laura, Valenzuela-Silva, Carmen, Paredes-Moreno, Beatriz, Sánchez-Ramírez, Belinda, Pérez-Nicado, Rocmira, González-Mugica, Raul, Hernández-García, Tays, Bergado-Baez, Gretchen, Pi-Estopiñán, Franciscary, Cruz-Sui, Otto, Fraga-Quintero, Anitza, García-Montero, Majela, Palenzuela-Díaz, Ariel, Baró-Román, Gerardo, Mendoza-Hernández, Ivis, Fernandez-Castillo, Sonsire, Climent-Ruiz, Yanet, Santana-Mederos, Darielys, Ramírez Gonzalez, Ubel, García-Vega, Yanelda, Pérez-Massón, Beatriz, Guang-Wu-Chen, Boggiano-Ayo, Tammy, Ojito-Magaz, Eduardo, Rivera, Daniel G., Valdés-Balbín, Yury, García-Rivera, Dagmar, Vérez-Bencomo, Vicente, Gómez-Maceo, Yanet, Reyes-Matienzo, Radamet, Manuel Coviella-Artime, José, Morffi-Cinta, Irania, Martínez-Pérez, Marisel, Castillo-Quintana, Ismavy, Garcés-Hechavarría, Aniurka, Valera-Fernández, Rodrigo, Martínez-Bedoya, Dayle, Garrido-Arteaga, Raine, Cardoso-SanJorge, Félix, Quintero Moreno, Lauren, Ontivero-Pino, Ivis, Teresa Pérez-Guevara, María, Morales-García, Marilin, Noa-Romero, Enrique, Orosa-Vázquez, Ivette, Díaz-Hernández, Marianniz, Rojas, Gertrudis, Tundidor, Yaima, García-López, Elena, Muñoz-Morejon, Yaima, Galano-Frutos, Evelyn, Rodríguez-Alvarez, Julián, Arteaga, Amaylid, Medina Nápoles, Maite, Espi Ávila, Jennifer, Fontanies Fernández, Marcos
Publicado 2022