HDAC inhibitors suppress protein poly(ADP-ribosyl)ation and DNA repair protein levels and phosphorylation status in hematologic cancer cells: implications for their use in combinat...

por Valdez, Benigno C., Nieto, Yago, Yuan, Bin, Murray, David, Andersson, Borje S.
Publicado 2022

ABT199/venetoclax potentiates the cytotoxicity of alkylating agents and fludarabine in acute myeloid leukemia cells

por Valdez, Benigno C., Murray, David, Yuan, Bin, Nieto, Yago, Popat, Uday, Andersson, Borje S.
Publicado 2022

Combination of a hypomethylating agent and inhibitors of PARP and HDAC traps PARP1 and DNMT1 to chromatin, acetylates DNA repair proteins, down-regulates NuRD and induces apoptosis...

por Valdez, Benigno C., Li, Yang, Murray, David, Liu, Yan, Nieto, Yago, Champlin, Richard E., Andersson, Borje S.
Publicado 2017

Differential effects of histone deacetylase inhibitors on cellular drug transporters and their implications for using epigenetic modifiers in combination chemotherapy

por Valdez, Benigno C., Li, Yang, Murray, David, Brammer, Jonathan E., Liu, Yan, Hosing, Chitra, Nieto, Yago, Champlin, Richard E., Andersson, Borje S.
Publicado 2016

Cytotoxicity of Gymnopilus purpureosquamulosus extracts on hematologic malignant cells through activation of the SAPK/JNK signaling pathway

por Dulay, Rich Milton, Valdez, Benigno C., Li, Yang, Chakrabarti, Seemanti, Dhillon, Braham, Kalaw, Sofronio P., Reyes, Renato G., Cabrera, Esperanza C.
Publicado 2021

Phase 2 Clinical Trial of High-Dose Gemcitabine/Busulfan/Melphalan for Autologous Stem-Cell Transplantation in Relapsed/Refractory Myeloma: Matched-Pair Comparison with Melphalan

por Nieto, Yago, Valdez, Benigno C, Pingali, Sai R, Bassett, Roland, Delgado, Ruby, Nguyen, John, Shah, Nina, Popat, Uday, Jones, Roy B, Andersson, Borje S, Gulbis, Alison, Ahmed, Sairah, Bashir, Qaiser, Parmar, Simrit, Patel, Krina, Myers, Alan, Rondon, Gabriela, Orlowski, Robert Z, Champlin, Richard, Qazilbash, Muzaffar
Publicado 2017

A randomized phase III study of pretransplant conditioning for AML/MDS with fludarabine and once daily IV busulfan ± clofarabine in allogeneic stem cell transplantation

por Andersson, Borje S., Thall, Peter F., Ma, Junsheng, Valdez, Benigno C., Bassett, Roland, Chen, Julianne, Ahmed, Sairah, Alousi, Amin, Bashir, Qaiser, Ciurea, Stefan, Gulbis, Alison, Cool, Rita, Kawedia, Jitesh, Hosing, Chitra, Kebriaei, Partow, Kornblau, Steve, Myers, Alan, Oran, Betul, Rezvani, Katayoun, Shah, Nina, Shpall, Elizabeth, Parmar, Simrit, Popat, Uday R., Nieto, Yago, Champlin, Richard E.
Publicado 2022

Fludarabine with pharmacokinetically-guided IV busulfan is superior to fixed-dose delivery in pretransplant conditioning of AML/MDS patients

por Andersson, Borje S., Thall, Peter F., Valdez, Benigno C., Milton, Denái R., Al-Atrash, Gheath, Chen, Julianne, Gulbis, Alison, Chu, Diem, Martinez, Charles, Parmar, Simrit, Popat, Uday, Nieto, Yago, Kebriaei, Partow, Alousi, Amin, de Lima, Marcos, Rondon, Gabriela, Meng, Qing H., Myers, Alan, Kawedia, Jitesh, Worth, Laura L., Fernandez-Vina, Marcelo, Madden, Timothy, Shpall, Elizabeth J., Jones, Roy B., Champlin, Richard E.
Publicado 2016

Improved outcomes of high-risk relapsed Hodgkin lymphoma patients after high-dose chemotherapy: a 15-year analysis

por Nieto, Yago, Gruschkus, Stephen, Valdez, Benigno C., Jones, Roy B., Anderlini, Paolo, Hosing, Chitra, Popat, Uday, Qazilbash, Muzaffar, Kebriaei, Partow, Alousi, Amin, Saini, Neeraj, Srour, Samer, Rezvani, Katayoun, Ramdial, Jeremy, Barnett, Melissa, Gulbis, Alison, Shigle, Terri Lynn, Ahmed, Sairah, Iyer, Swaminathan, Lee, Hun, Nair, Ranjit, Parmar, Simrit, Steiner, Raphael, Dabaja, Bouthaina, Pinnix, Chelsea, Gunther, Jillian, Cuglievan, Branko, Mahadeo, Kris, Khazal, Sajad, Chuang, Hubert, Champlin, Richard, Shpall, Elizabeth J., Andersson, Borje S.
Publicado 2021