Orally administered branaplam does not impact neurogenesis in juvenile mice, rats, and dogs

por Theil, Diethilde, Valdez, Reginald, Darribat, Katy, Doelemeyer, Arno, Sivasankaran, Rajeev, Hartmann, Andreas
Publicado 2021

TMEM203 Is a Novel Regulator of Intracellular Calcium Homeostasis and Is Required for Spermatogenesis

por Shambharkar, Prashant B., Bittinger, Mark, Latario, Brian, Xiong, ZhaoHui, Bandyopadhyay, Somnath, Davis, Vanessa, Lin, Victor, Yang, Yi, Valdez, Reginald, Labow, Mark A.
Publicado 2015

The Histone H3K79 Methyltransferase Dot1L Is Essential for Mammalian Development and Heterochromatin Structure

por Jones, Brendan, Su, Hui, Bhat, Audesh, Lei, Hong, Bajko, Jeffrey, Hevi, Sarah, Baltus, Gretchen A., Kadam, Shilpa, Zhai, Huili, Valdez, Reginald, Gonzalo, Susana, Zhang, Yi, Li, En, Chen, Taiping
Publicado 2008

Short-term Low-Dose mTORC1 Inhibition in Aged Rats Counter-Regulates Age-Related Gene Changes and Blocks Age-Related Kidney Pathology

por Shavlakadze, Tea, Zhu, Jiang, Wang, Sharon, Zhou, Weihua, Morin, Bret, Egerman, Marc A, Fan, Lin, Wang, Yanqun, Iartchouk, Oleg, Meyer, Angelika, Valdez, Reginald A, Mannick, Joan B, Klickstein, Lloyd B, Glass, David J
Publicado 2018

Farnesoid X Receptor Agonism, Acetyl‐Coenzyme A Carboxylase Inhibition, and Back Translation of Clinically Observed Endpoints of De Novo Lipogenesis in a Murine NASH Model

por Gapp, Berangere, Jourdain, Marie, Bringer, Pauline, Kueng, Benjamin, Weber, Delphine, Osmont, Arnaud, Zurbruegg, Stefan, Knehr, Judith, Falchetto, Rocco, Roma, Guglielmo, Dietrich, William, Valdez, Reginald, Beckmann, Nicolau, Nigsch, Florian, Sanyal, Arun J., Ksiazek, Iwona
Publicado 2019

A Hypomorphic Lsd1 Allele Results in Heart Development Defects in Mice

por Nicholson, Thomas B., Singh, Anup K., Su, Hui, Hevi, Sarah, Wang, Jing, Bajko, Jeff, Li, Mei, Valdez, Reginald, Goetschkes, Margaret, Capodieci, Paola, Loureiro, Joseph, Cheng, Xiaodong, Li, En, Kinzel, Bernd, Labow, Mark, Chen, Taiping
Publicado 2013

Tropifexor‐Mediated Abrogation of Steatohepatitis and Fibrosis Is Associated With the Antioxidative Gene Expression Profile in Rodents

por Hernandez, Eloy D., Zheng, Lianxing, Kim, Young, Fang, Bin, Liu, Bo, Valdez, Reginald A., Dietrich, William F., Rucker, Paul V., Chianelli, Donatella, Schmeits, James, Bao, Dingjiu, Zoll, Jocelyn, Dubois, Claire, Federe, Glenn C., Chen, Lihao, Joseph, Sean B., Klickstein, Lloyd B., Walker, John, Molteni, Valentina, McNamara, Peter, Meeusen, Shelly, Tully, David C., Badman, Michael K., Xu, Jie, Laffitte, Bryan
Publicado 2019