Ontogeny of CYP3A and UGT activity in preterm piglets: a translational model for drug metabolism in preterm newborns

por Buyssens, Laura, Valenzuela, Allan, Prims, Sara, Ayuso, Miriam, Thymann, Thomas, Van Ginneken, Chris, Van Cruchten, Steven
Publicado 2023

Platelet Activation by Antisense Oligonucleotides (ASOs) in the Göttingen Minipig, including an Evaluation of Glycoprotein VI (GPVI) and Platelet Factor 4 (PF4) Ontogeny

por Valenzuela, Allan, Ayuso, Miriam, Buyssens, Laura, Bars, Chloé, Van Ginneken, Chris, Tessier, Yann, Van Cruchten, Steven
Publicado 2023

Developmental Toxicity and Biotransformation of Two Anti-Epileptics in Zebrafish Embryos and Early Larvae

por Bars, Chloé, Hoyberghs, Jente, Valenzuela, Allan, Buyssens, Laura, Ayuso, Miriam, Van Ginneken, Chris, Labro, Alain J., Foubert, Kenn, Van Cruchten, Steven J.
Publicado 2021

The Neonatal and Juvenile Pig in Pediatric Drug Discovery and Development

por Ayuso, Miriam, Buyssens, Laura, Stroe, Marina, Valenzuela, Allan, Allegaert, Karel, Smits, Anne, Annaert, Pieter, Mulder, Antonius, Carpentier, Sebastien, Van Ginneken, Chris, Van Cruchten, Steven
Publicado 2020

Development of a neonatal Göttingen Minipig model for dose precision in perinatal asphyxia: technical opportunities, challenges, and potential further steps

por Stroe, Marina-Stefania, Van Bockstal, Lieselotte, Valenzuela, Allan, Ayuso, Miriam, Leys, Karen, Annaert, Pieter, Carpentier, Sebastien, Smits, Anne, Allegaert, Karel, Zeltner, Adrian, Mulder, Antonius, Van Ginneken, Chris, Van Cruchten, Steven
Publicado 2023

Safety Testing of an Antisense Oligonucleotide Intended for Pediatric Indications in the Juvenile Göttingen Minipig, including an Evaluation of the Ontogeny of Key Nucleases

por Valenzuela, Allan, Tardiveau, Claire, Ayuso, Miriam, Buyssens, Laura, Bars, Chloe, Van Ginneken, Chris, Fant, Pierluigi, Leconte, Isabelle, Braendli-Baiocco, Annamaria, Parrott, Neil, Schmitt, Georg, Tessier, Yann, Barrow, Paul, Van Cruchten, Steven
Publicado 2021