Active Fragments from Pro- and Antiapoptotic BCL-2 Proteins Have Distinct Membrane Behavior Reflecting Their Functional Divergence

por Guillemin, Yannis, Lopez, Jonathan, Gimenez, Diana, Fuertes, Gustavo, Valero, Juan Garcia, Blum, Loïc, Gonzalo, Philippe, Salgado, Jesùs, Girard-Egrot, Agnès, Aouacheria, Abdel
Publicado 2010

µ-Calpain Conversion of Antiapoptotic Bfl-1 (BCL2A1) into a Prodeath Factor Reveals Two Distinct alpha-Helices Inducing Mitochondria-Mediated Apoptosis

por Valero, Juan García, Cornut-Thibaut, Aurélie, Jugé, Romain, Debaud, Anne-Laure, Giménez, Diana, Gillet, Germain, Bonnefoy-Bérard, Nathalie, Salgado, Jesús, Salles, Gilles, Aouacheria, Abdel, Kucharczak, Jérôme
Publicado 2012

Venetoclax improves CD20 immunotherapy in a mouse model of MYC/BCL2 double-expressor diffuse large B-cell lymphoma

por Melchor, Javier, Garcia-Lacarte, Marcos, Grijalba, Sara C., Arnaiz-Leché, Adrián, Pascual, Marién, Panizo, Carlos, Blanco, Oscar, Segura, Victor, Novo, Francisco J., Valero, Juan Garcia, Pérez-Galán, Patricia, Martinez-Climent, Jose A., Roa, Sergio
Publicado 2023

Apaf-1 Inhibitors Protect from Unwanted Cell Death in In Vivo Models of Kidney Ischemia and Chemotherapy Induced Ototoxicity

por Orzáez, Mar, Sancho, Mónica, Marchán, Sandra, Mondragón, Laura, Montava, Rebeca, Valero, Juan García, Landeta, Olatz, Basañez, Gorka, Carbajo, Rodrigo J., Pineda-Lucena, Antonio, Bujons, Jordi, Moure, Alejandra, Messeguer, Angel, Lagunas, Carmen, Herrero, Carmen, Pérez-Payá, Enrique
Publicado 2014

Patient-derived lymphoma spheroids integrating immune tumor microenvironment as preclinical follicular lymphoma models for personalized medicine

por Faria, Carla, Gava, Fabien, Gravelle, Pauline, Valero, Juan Garcia, Dobaño-López, Celia, Van Acker, Nathalie, Quelen, Cathy, Jalowicki, Gael, Morin, Renaud, Rossi, Cédric, Lagarde, Jean-Michel, Fournié, Jean-Jacques, Ysebaert, Loïc, Laurent, Camille, Pérez-Galán, Patricia, Bezombes, Christine
Publicado 2023

A novel patient-derived 3D model recapitulates mantle cell lymphoma lymph node signaling, immune profile and in vivo ibrutinib responses

por Araujo-Ayala, Ferran, Dobaño-López, Cèlia, Valero, Juan García, Nadeu, Ferran, Gava, Fabien, Faria, Carla, Norlund, Marine, Morin, Renaud, Bernes-Lasserre, Pascale, Serrat, Neus, Playa-Albinyana, Heribert, Giménez, Rubén, Campo, Elías, Lagarde, Jean-Michel, López-Guillermo, Armando, Gine, Eva, Colomer, Dolors, Bezombes, Christine, Pérez-Galán, Patricia
Publicado 2023

The receptor of the colony-stimulating factor-1 (CSF-1R) is a novel prognostic factor and therapeutic target in follicular lymphoma

por Valero, Juan Garcia, Matas-Céspedes, Alba, Arenas, Fabián, Rodriguez, Vanina, Carreras, Joaquim, Serrat, Neus, Guerrero-Hernández, Martina, Yahiaoui, Anella, Balagué, Olga, Martin, Silvia, Capdevila, Cristina, Hernández, Lluis, Magnano, Laura, Rivas-Delgado, Alfredo, Tannheimer, Stacey, Cid, Maria C., Campo, Elías, López-Guillermo, Armando, Colomer, Dolors, Pérez-Galán, Patricia
Publicado 2021