Targeting of elevated cell surface phosphatidylserine with saposin C-dioleoylphosphatidylserine nanodrug as individual or combination therapy for pancreatic cancer

por Davis, Harold W, Kaynak, Ahmet, Vallabhapurapu, Subrahmanya D, Qi, Xiaoyang
Publicado 2021

SapC-DOPS nanovesicles induce Smac- and Bax-dependent apoptosis through mitochondrial activation in neuroblastomas

por Sulaiman, Mahaboob K, Chu, Zhengtao, Blanco, Victor M, Vallabhapurapu, Subrahmanya D, Franco, Robert S, Qi, Xiaoyang
Publicado 2015

SapC–DOPS as a Novel Therapeutic and Diagnostic Agent for Glioblastoma Therapy and Detection: Alternative to Old Drugs and Agents

por Kaynak, Ahmet, Davis, Harold W., Vallabhapurapu, Subrahmanya D., Pak, Koon Y., Gray, Brian D., Qi, Xiaoyang
Publicado 2021

Variation in human cancer cell external phosphatidylserine is regulated by flippase activity and intracellular calcium

por Vallabhapurapu, Subrahmanya D., Blanco, Víctor M., Sulaiman, Mahaboob K., Vallabhapurapu, Swarajya Lakshmi, Chu, Zhengtao, Franco, Robert S., Qi, Xiaoyang
Publicado 2015

Transcriptional Repression of Bim by a Novel YY1-RelA Complex Is Essential for the Survival and Growth of Multiple Myeloma

por Potluri, Veena, Noothi, Sunil K., Vallabhapurapu, Subrahmanya D., Yoon, Sang-Oh, Driscoll, James J., Lawrie, Charles H., Vallabhapurapu, Sivakumar
Publicado 2013

Phosphatidylserine-selective targeting and anticancer effects of SapC-DOPS nanovesicles on brain tumors

por Blanco, Víctor M., Chu, Zhengtao, Vallabhapurapu, Subrahmanya D., Sulaiman, Mahaboob K., Kendler, Ady, Rixe, Olivier, Warnick, Ronald E., Franco, Robert S., Qi, Xiaoyang
Publicado 2014

Enhanced phosphatidylserine-selective cancer therapy with irradiation and SapC-DOPS nanovesicles

por Davis, Harold W., Vallabhapurapu, Subrahmanya D., Chu, Zhengtao, Vallabhapurapu, Swarajya L., Franco, Robert S., Mierzwa, Michelle, Kassing, William, Barrett, William L., Qi, Xiaoyang
Publicado 2019

Biotherapy of Brain Tumors with Phosphatidylserine-Targeted Radioiodinated SapC-DOPS Nanovesicles

por Davis, Harold W., Vallabhapurapu, Subrahmanya D., Chu, Zhengtao, Wyder, Michael A., Greis, Kenneth D., Fannin, Venette, Sun, Ying, Desai, Pankaj B., Pak, Koon Y., Gray, Brian D., Qi, Xiaoyang
Publicado 2020

Lack of NFATc1 SUMOylation prevents autoimmunity and alloreactivity

por Xiao, Yin, Qureischi, Musga, Dietz, Lena, Vaeth, Martin, Vallabhapurapu, Subrahmanya D., Klein-Hessling, Stefan, Klein, Matthias, Liang, Chunguang, König, Anika, Serfling, Edgar, Mottok, Anja, Bopp, Tobias, Rosenwald, Andreas, Buttmann, Mathias, Berberich, Ingolf, Beilhack, Andreas, Berberich-Siebelt, Friederike
Publicado 2020