Pharmacokinetics and pharmacodynamics in the treatment of cutaneous leishmaniasis – challenges and opportunities

por Van Bocxlaer, Katrien, Croft, Simon L.
Publicado 2021

Activity of Amphotericin B-Loaded Chitosan Nanoparticles against Experimental Cutaneous Leishmaniasis

por Riezk, Alaa, Van Bocxlaer, Katrien, Yardley, Vanessa, Murdan, Sudaxshina, Croft, Simon L.
Publicado 2020

Efficacy of Paromomycin-Chloroquine Combination Therapy in Experimental Cutaneous Leishmaniasis

por Wijnant, Gert-Jan, Van Bocxlaer, Katrien, Yardley, Vanessa, Murdan, Sudaxshina, Croft, Simon L.
Publicado 2017

Relation between Skin Pharmacokinetics and Efficacy in AmBisome Treatment of Murine Cutaneous Leishmaniasis

por Wijnant, Gert-Jan, Van Bocxlaer, Katrien, Yardley, Vanessa, Harris, Andy, Murdan, Sudaxshina, Croft, Simon L.
Publicado 2018

Film-Forming Systems for the Delivery of DNDI-0690 to Treat Cutaneous Leishmaniasis

por Van Bocxlaer, Katrien, McArthur, Kerri-Nicola, Harris, Andy, Alavijeh, Mo, Braillard, Stéphanie, Mowbray, Charles E., Croft, Simon L.
Publicado 2021

Local Skin Inflammation in Cutaneous Leishmaniasis as a Source of Variable Pharmacokinetics and Therapeutic Efficacy of Liposomal Amphotericin B

por Wijnant, Gert-Jan, Van Bocxlaer, Katrien, Fortes Francisco, Amanda, Yardley, Vanessa, Harris, Andy, Alavijeh, Mo, Murdan, Sudaxshina, Croft, Simon L.
Publicado 2018

Pharmacokinetics and Pharmacodynamics of the Nitroimidazole DNDI-0690 in Mouse Models of Cutaneous Leishmaniasis

por Wijnant, Gert-Jan, Croft, Simon L., de la Flor, Raul, Alavijeh, Mo, Yardley, Vanessa, Braillard, Stéphanie, Mowbray, Charles, Van Bocxlaer, Katrien
Publicado 2019

Efficacy of oleylphosphocholine in experimental cutaneous leishmaniasis

por Van Bocxlaer, Katrien, Dixon, Jodie, Platteeuw, Johannes J, Van Den Heuvel, Dennie, Mcarthur, Kerri-Nicola, Harris, Andy, Alavijeh, Mo, Croft, Simon L, Yardley, Vanessa
Publicado 2023

Comparative efficacy, toxicity and biodistribution of the liposomal amphotericin B formulations Fungisome(®) and AmBisome(®) in murine cutaneous leishmaniasis

por Wijnant, Gert-Jan, Van Bocxlaer, Katrien, Yardley, Vanessa, Harris, Andy, Alavijeh, Mo, Silva-Pedrosa, Rita, Antunes, Sandra, Mauricio, Isabel, Murdan, Sudaxshina, Croft, Simon L.
Publicado 2018

Route map for the discovery and pre-clinical development of new drugs and treatments for cutaneous leishmaniasis

por Caridha, Diana, Vesely, Brian, van Bocxlaer, Katrien, Arana, Byron, Mowbray, Charles E., Rafati, Sima, Uliana, Silvia, Reguera, Rosa, Kreishman-Deitrick, Mara, Sciotti, Richard, Buffet, Pierre, Croft, Simon L.
Publicado 2019

Novel benzoxaborole, nitroimidazole and aminopyrazoles with activity against experimental cutaneous leishmaniasis

por Van Bocxlaer, Katrien, Caridha, Diana, Black, Chad, Vesely, Brian, Leed, Susan, Sciotti, Richard J., Wijnant, Gert-Jan, Yardley, Vanessa, Braillard, Stéphanie, Mowbray, Charles E., Ioset, Jean-Robert, Croft, Simon L.
Publicado 2019

Characterization of a new Leishmania major strain for use in a controlled human infection model

por Ashwin, Helen, Sadlova, Jovana, Vojtkova, Barbora, Becvar, Tomas, Lypaczewski, Patrick, Schwartz, Eli, Greensted, Elizabeth, Van Bocxlaer, Katrien, Pasin, Marion, Lipinski, Kai S., Parkash, Vivak, Matlashewski, Greg, Layton, Alison M., Lacey, Charles J., Jaffe, Charles L., Volf, Petr, Kaye, Paul M.
Publicado 2021

A single dose of antibody-drug conjugate cures a stage 1 model of African trypanosomiasis

por MacGregor, Paula, Gonzalez-Munoz, Andrea L., Jobe, Fatoumatta, Taylor, Martin C., Rust, Steven, Sandercock, Alan M., Macleod, Olivia J. S., Van Bocxlaer, Katrien, Francisco, Amanda F., D’Hooge, Francois, Tiberghien, Arnaud, Barry, Conor S., Howard, Philip, Higgins, Matthew K., Vaughan, Tristan J., Minter, Ralph, Carrington, Mark
Publicado 2019