Complement inhibition prevents glial nodal membrane injury in a GM1 antibody-mediated mouse model

por Campbell, Clare I, McGonigal, Rhona, Barrie, Jennifer A, Delaere, Jolien, Bracke, Laura, Cunningham, Madeleine E, Yao, Denggao, Delahaye, Tim, Van de Walle, Inge, Willison, Hugh J
Publicado 2022

PHF6 Expression Levels Impact Human Hematopoietic Stem Cell Differentiation

por Loontiens, Siebe, Dolens, Anne-Catherine, Strubbe, Steven, Van de Walle, Inge, Moore, Finola E., Depestel, Lisa, Vanhauwaert, Suzanne, Matthijssens, Filip, Langenau, David M., Speleman, Frank, Van Vlierberghe, Pieter, Durinck, Kaat, Taghon, Tom
Publicado 2020

Specific Notch receptor–ligand interactions control human TCR-αβ/γδ development by inducing differential Notch signal strength

por Van de Walle, Inge, Waegemans, Els, De Medts, Jelle, De Smet, Greet, De Smedt, Magda, Snauwaert, Sylvia, Vandekerckhove, Bart, Kerre, Tessa, Leclercq, Georges, Plum, Jean, Gridley, Thomas, Wang, Tao, Koch, Ute, Radtke, Freddy, Taghon, Tom
Publicado 2013

Primate lentiviral Nef proteins deregulate T-cell development by multiple mechanisms

por Van Nuffel, Anouk, Ariën, Kevin K, Stove, Veronique, Schindler, Michael, O’Neill, Eduardo, Schmökel, Jan, Van de Walle, Inge, Naessens, Evelien, Vanderstraeten, Hanne, Van Landeghem, Kathleen, Taghon, Tom, Pulkkinen, Kati, Saksela, Kalle, Garcia, J Victor, Fackler, Oliver T, Kirchhoff, Frank, Verhasselt, Bruno
Publicado 2013

A novel tumor suppressor function for the Notch pathway in myeloid leukemia

por Klinakis, Apostolos, Lobry, Camille, Abdel-Wahab, Omar, Oh, Philmo, Haeno, Hiroshi, Buonamici, Silvia, van De Walle, Inge, Cathelin, Severine, Trimarchi, Thomas, Araldi, Elisa, Liu, Cynthia, Ibrahim, Sherif, Beran, Miroslav, Zavadil, Jiri, Efstratiadis, Argiris, Taghon, Tom, Michor, Franziska, Levine, Ross L., Aifantis, Iannis
Publicado 2011

GATA3 induces human T-cell commitment by restraining Notch activity and repressing NK-cell fate

por Van de Walle, Inge, Dolens, Anne-Catherine, Durinck, Kaat, De Mulder, Katrien, Van Loocke, Wouter, Damle, Sagar, Waegemans, Els, De Medts, Jelle, Velghe, Imke, De Smedt, Magda, Vandekerckhove, Bart, Kerre, Tessa, Plum, Jean, Leclercq, Georges, Rothenberg, Ellen V., Van Vlierberghe, Pieter, Speleman, Frank, Taghon, Tom
Publicado 2016

Selective inhibition of TGF-β1 produced by GARP-expressing Tregs overcomes resistance to PD-1/PD-L1 blockade in cancer

por de Streel, Grégoire, Bertrand, Charlotte, Chalon, Nicolas, Liénart, Stéphanie, Bricard, Orian, Lecomte, Sara, Devreux, Julien, Gaignage, Mélanie, De Boeck, Gitte, Mariën, Lore, Van De Walle, Inge, van der Woning, Bas, Saunders, Michael, de Haard, Hans, Vermeersch, Elien, Maes, Wim, Deckmyn, Hans, Coulie, Pierre G., van Baren, Nicolas, Lucas, Sophie
Publicado 2020

ARGX-117, a therapeutic complement inhibiting antibody targeting C2

por Van de Walle, Inge, Silence, Karen, Budding, Kevin, Van de Ven, Liesbeth, Dijkxhoorn, Kim, de Zeeuw, Elisabeth, Yildiz, Cafer, Gabriels, Sofie, Percier, Jean-Michel, Wildemann, Johanna, Meeldijk, Jan, Simons, Peter J., Boon, Louis, Cox, Linda, Holgate, Rob, Urbanus, Rolf, Otten, Henny G., Leusen, Jeanette H.W., Blanchetot, Christophe, de Haard, Hans, Hack, C. Erik, Boross, Peter
Publicado 2020

Anti-C2 Antibody ARGX-117 Inhibits Complement in a Disease Model for Multifocal Motor Neuropathy

por Budding, Kevin, Johansen, Lill Eva, Van de Walle, Inge, Dijkxhoorn, Kim, de Zeeuw, Elisabeth, Bloemenkamp, Lauri M., Bos, Jeroen W., Jansen, Marc D., Curial, Chantall A.D., Silence, Karen, de Haard, Hans, Blanchetot, Christophe, Van de Ven, Liesbeth, Leusen, Jeanette H.W., Pasterkamp, R. Jeroen, van den Berg, Leonard H., Hack, C. Erik, Boross, Peter, van der Pol, W. Ludo
Publicado 2021