Bcl-2–regulated apoptosis and cytochrome c release can occur independently of both caspase-2 and caspase-9

por Marsden, Vanessa S., Ekert, Paul G., Van Delft, Mark, Vaux, David L., Adams, Jerry M., Strasser, Andreas
Publicado 2004

BAK/BAX-Mediated Apoptosis Is a Myc-Induced Roadblock to Reprogramming

por Kim, Esther J.Y., Anko, Minna-Liisa, Flensberg, Christoffer, Majewski, Ian J., Geng, Fan-Suo, Firas, Jaber, Huang, David C.S., van Delft, Mark F., Heath, Joan K.
Publicado 2018

MARCH5 requires MTCH2 to coordinate proteasomal turnover of the MCL1:NOXA complex

por Djajawi, Tirta Mario, Liu, Lei, Gong, Jia-nan, Huang, Allan Shuai, Luo, Ming-jie, Xu, Zhen, Okamoto, Toru, Call, Melissa J., Huang, David C. S., van Delft, Mark F.
Publicado 2020

A novel BH3 ligand that selectively targets Mcl-1 reveals that apoptosis can proceed without Mcl-1 degradation

por Lee, Erinna F., Czabotar, Peter E., van Delft, Mark F., Michalak, Ewa M., Boyle, Michelle J., Willis, Simon N., Puthalakath, Hamsa, Bouillet, Philippe, Colman, Peter M., Huang, David C.S., Fairlie, W. Douglas
Publicado 2008

SMYD2 lysine methyltransferase regulates leukemia cell growth and regeneration after genotoxic stress

por Zipin-Roitman, Adi, Aqaqe, Nasma, Yassin, Muhammad, Biechonski, Shahar, Amar, Mariam, van Delft, Mark F., Gan, Olga I., McDermott, Sean P., Buzina, Alla, Ketela, Troy, Shlush, Liran, Xie, Stephanie, Voisin, Veronique, Moffat, Jason, Minden, Mark D., Dick, John E., Milyavsky, Michael
Publicado 2017

The Lck inhibitor, AMG-47a, blocks necroptosis and implicates RIPK1 in signalling downstream of MLKL

por Jacobsen, Annette V., Pierotti, Catia L., Lowes, Kym N., Au, Amanda E., Zhang, Ying, Etemadi, Nima, Fitzgibbon, Cheree, Kersten, Wilhelmus J. A., Samson, André L., van Delft, Mark F., Huang, David C. S., Sabroux, Hélène Jousset, Lessene, Guillaume, Silke, John, Murphy, James M.
Publicado 2022

The VEGFR/PDGFR tyrosine kinase inhibitor, ABT-869, blocks necroptosis by targeting RIPK1 kinase

por Pierotti, Catia L., Jacobsen, Annette V., Grohmann, Christoph, Dempsey, Ruby K., Etemadi, Nima, Hildebrand, Joanne M., Fitzgibbon, Cheree, Young, Samuel N., Davies, Katherine A., Kersten, Wilhelmus J. A., Silke, John, Lowes, Kym N., Jousset Sabroux, Hélène, Huang, David C. S., van Delft, Mark F., Murphy, James M., Lessene, Guillaume
Publicado 2023

VDAC2 enables BAX to mediate apoptosis and limit tumor development

por Chin, Hui San, Li, Mark X., Tan, Iris K. L., Ninnis, Robert L., Reljic, Boris, Scicluna, Kristen, Dagley, Laura F., Sandow, Jarrod J., Kelly, Gemma L., Samson, Andre L., Chappaz, Stephane, Khaw, Seong L., Chang, Catherine, Morokoff, Andrew, Brinkmann, Kerstin, Webb, Andrew, Hockings, Colin, Hall, Cathrine M., Kueh, Andrew J., Ryan, Michael T., Kluck, Ruth M., Bouillet, Philippe, Herold, Marco J., Gray, Daniel H. D., Huang, David C. S., van Delft, Mark F., Dewson, Grant
Publicado 2018