PIK3R3 is a candidate regulator of platelet count in people of Bangladeshi ancestry

por Burley, Kate, Fitzgibbon, Lucy, van Heel, David, Vuckovic, Dragana, Mumford, Andrew D.
Publicado 2023

SLCO1B1*5 is protective against non-senile cataracts in cohort prescribed statins: analysis in a British-South Asian cohort

por Magavern, Emma F., van Heel, David A., Smedley, Damian, Caulfield, Mark J.
Publicado 2023

No Evidence in a Large UK Collection for Celiac Disease Risk Variants Reported by a Spanish Study

por Hunt, Karen A., Franke, Lude, Deloukas, Panos, Wijmenga, Cisca, van Heel, David A.
Publicado 2008

Rare variant contribution to cholestatic liver disease in a South Asian population in the United Kingdom

por Zöllner, Julia, Finer, Sarah, Linton, Kenneth J., van Heel, David A., Williamson, Catherine, Dixon, Peter H.
Publicado 2023

Polygenic risk score prediction of multiple sclerosis in individuals of South Asian ancestry

por Breedon, Joshua R, Marshall, Charles R, Giovannoni, Gavin, van Heel, David A, Dobson, Ruth, Jacobs, Benjamin M
Publicado 2023

CYP2C19 Genotype Prevalence and Association With Recurrent Myocardial Infarction in British–South Asians Treated With Clopidogrel

por Magavern, Emma F., Jacobs, Benjamin, Warren, Helen, Finocchiaro, Gherardo, Finer, Sarah, van Heel, David A., Smedley, Damian, Caulfield, Mark J.
Publicado 2023

Complex nature of SNP genotype effects on gene expression in primary human leucocytes

por Heap, Graham A, Trynka, Gosia, Jansen, Ritsert C, Bruinenberg, Marcel, Swertz, Morris A, Dinesen, Lotte C, Hunt, Karen A, Wijmenga, Cisca, vanHeel, David A, Franke, Lude
Publicado 2009

Integrative polygenic risk score improves the prediction accuracy of complex traits and diseases

por Truong, Buu, Hull, Leland E., Ruan, Yunfeng, Huang, Qin Qin, Hornsby, Whitney, Martin, Hilary, van Heel, David A., Wang, Ying, Martin, Alicia R., Lee, S. Hong, Natarajan, Pradeep
Publicado 2023

Fine-mapping in the MHC region accounts for 18% additional genetic risk for celiac disease

por Gutierrez-Achury, Javier, Zhernakova, Alexandra, Pulit, Sara L., Trynka, Gosia, Hunt, Karen A., Romanos, Jihane, Raychaudhuri, Soumya, van Heel, David A., Wijmenga, Cisca, de Bakker, Paul I.W.
Publicado 2015

Effective Detection of Human Leukocyte Antigen Risk Alleles in Celiac Disease Using Tag Single Nucleotide Polymorphisms

por Monsuur, Alienke J., de Bakker, Paul I. W., Zhernakova, Alexandra, Pinto, Dalila, Verduijn, Willem, Romanos, Jihane, Auricchio, Renata, Lopez, Ana, van Heel, David A., Crusius, J. Bart A, Wijmenga, Cisca
Publicado 2008

Correction: Effective Detection of Human Leukocyte Antigen Risk Alleles in Celiac Disease Using Tag Single Nucleotide Polymorphisms

por Monsuur, Alienke J., de Bakker, Paul I. W., Zhernakova, Alexandra, Pinto, Dalila, Verduijn, Willem, Romanos, Jihane, Auricchio, Renata, Lopez, Ana, van Heel, David A., Crusius, J. Bart A, Wijmenga, Cisca
Publicado 2009

Exome Sequencing of 75 Individuals from Multiply Affected Coeliac Families and Large Scale Resequencing Follow Up

por Mistry, Vanisha, Bockett, Nicholas A., Levine, Adam P., Mirza, Muddassar M., Hunt, Karen A., Ciclitira, Paul J., Hummerich, Holger, Neuhausen, Susan L., Simpson, Michael A., Plagnol, Vincent, van Heel, David A.
Publicado 2015

Integrating polygenic risk scores in the prediction of type 2 diabetes risk and subtypes in British Pakistanis and Bangladeshis: A population-based cohort study

por Hodgson, Sam, Huang, Qin Qin, Sallah, Neneh, Griffiths, Chris J., Newman, William G., Trembath, Richard C., Wright, John, Lumbers, R. Thomas, Kuchenbaecker, Karoline, van Heel, David A., Mathur, Rohini, Martin, Hilary C., Finer, Sarah
Publicado 2022

Estimating the human mutation rate from autozygous segments reveals population differences in human mutational processes

por Narasimhan, Vagheesh M., Rahbari, Raheleh, Scally, Aylwyn, Wuster, Arthur, Mason, Dan, Xue, Yali, Wright, John, Trembath, Richard C., Maher, Eamonn R., van Heel, David A., Auton, Adam, Hurles, Matthew E., Tyler-Smith, Chris, Durbin, Richard
Publicado 2017

Evaluating drug targets through human loss-of-function genetic variation

por Minikel, Eric Vallabh, Karczewski, Konrad J., Martin, Hilary C., Cummings, Beryl B., Whiffin, Nicola, Rhodes, Daniel, Alföldi, Jessica, Trembath, Richard C., van Heel, David A., Daly, Mark J., Schreiber, Stuart L., MacArthur, Daniel G.
Publicado 2020

Author Correction: Evaluating drug targets through human loss-of-function genetic variation

por Minikel, Eric Vallabh, Karczewski, Konrad J., Martin, Hilary C., Cummings, Beryl B., Whiffin, Nicola, Rhodes, Daniel, Alföldi, Jessica, Trembath, Richard C., van Heel, David A., Daly, Mark J., Schreiber, Stuart L., MacArthur, Daniel G.
Publicado 2021

The combination of transcriptomics and informatics identifies pathways targeted by miR-204 during neurogenesis and axon guidance

por Conte, Ivan, Merella, Stefania, Garcia-Manteiga, Jose Manuel, Migliore, Chiara, Lazarevic, Dejan, Carrella, Sabrina, Marco-Ferreres, Raquel, Avellino, Raffaella, Davidson, Nathan Paul, Emmett, Warren, Sanges, Remo, Bockett, Nicholas, Van Heel, David, Meroni, Germana, Bovolenta, Paola, Stupka, Elia, Banfi, Sandro
Publicado 2014

Fine-scale population structure and demographic history of British Pakistanis

por Arciero, Elena, Dogra, Sufyan A., Malawsky, Daniel S., Mezzavilla, Massimo, Tsismentzoglou, Theofanis, Huang, Qin Qin, Hunt, Karen A., Mason, Dan, Sharif, Saghira Malik, van Heel, David A., Sheridan, Eamonn, Wright, John, Small, Neil, Carmi, Shai, Iles, Mark M., Martin, Hilary C.
Publicado 2021

Cohort Profile: East London Genes & Health (ELGH), a community-based population genomics and health study in British Bangladeshi and British Pakistani people

por Finer, Sarah, Martin, Hilary C, Khan, Ahsan, Hunt, Karen A, MacLaughlin, Beverley, Ahmed, Zaheer, Ashcroft, Richard, Durham, Ceri, MacArthur, Daniel G, McCarthy, Mark I, Robson, John, Trivedi, Bhavi, Griffiths, Chris, Wright, John, Trembath, Richard C, van Heel, David A
Publicado 2020

Transferability of genetic loci and polygenic scores for cardiometabolic traits in British Pakistani and Bangladeshi individuals

por Huang, Qin Qin, Sallah, Neneh, Dunca, Diana, Trivedi, Bhavi, Hunt, Karen A., Hodgson, Sam, Lambert, Samuel A., Arciero, Elena, Wright, John, Griffiths, Chris, Trembath, Richard C., Hemingway, Harry, Inouye, Michael, Finer, Sarah, van Heel, David A., Lumbers, R. Thomas, Martin, Hilary C., Kuchenbaecker, Karoline
Publicado 2022