Subcutaneous Sarilumab in Patients With Rheumatoid Arthritis who Previously Received Subcutaneous Sarilumab or Intravenous Tocilizumab: An Open‐Label Extension of a Randomized Clin...

por Emery, Paul, van Hoogstraten, Hubert, Thangavelu, Karthinathan, Mangan, Erin, St John, Gregory, Verschueren, Patrick
Publicado 2020

Sarilumab plus methotrexate in patients with active rheumatoid arthritis and inadequate response to methotrexate: results of a randomized, placebo-controlled phase III trial in Jap...

por Tanaka, Yoshiya, Wada, Kazuteru, Takahashi, Yoshinori, Hagino, Owen, van Hoogstraten, Hubert, Graham, Neil M. H., Kameda, Hideto
Publicado 2019

Correction to: Sarilumab plus methotrexate in patients with active rheumatoid arthritis and inadequate response to methotrexate: results of a randomized, placebo-controlled phase I...

por Tanaka, Yoshiya, Wada, Kazuteru, Takahashi, Yoshinori, Hagino, Owen, van Hoogstraten, Hubert, Graham, Neil M. H., Kameda, Hideto
Publicado 2019

Disproportionate articular pain is a frequent phenomenon in rheumatoid arthritis and responds to treatment with sarilumab

por Choy, Ernest, Bykerk, Vivian, Lee, Yvonne C, van Hoogstraten, Hubert, Ford, Kerri, Praestgaard, Amy, Perrot, Serge, Pope, Janet, Sebba, Anthony
Publicado 2022

Long-term safety and efficacy of sarilumab with or without background csDMARDs in rheumatoid arthritis

por Burmester, Gerd R, Strand, Vibeke, Kivitz, Alan J, Hu, Chih-Chi, Wang, Sheldon, van Hoogstraten, Hubert, Klier, Gabriella L, Fleischmann, Roy
Publicado 2023

Real-World Sarilumab Use and Rule Testing to Predict Treatment Response in Patients with Rheumatoid Arthritis: Findings from the RISE Registry

por Curtis, Jeffrey R., Yun, Huifeng, Chen, Lang, Ford, Stephanie S., van Hoogstraten, Hubert, Fiore, Stefano, Ford, Kerri, Praestgaard, Amy, Rehberg, Markus, Choy, Ernest
Publicado 2023

Pharmacokinetics and Pharmacodynamics of Subcutaneous Sarilumab and Intravenous Tocilizumab Following Single‐Dose Administration in Patients With Active Rheumatoid Arthritis on Sta...

por Paccaly, Anne J., Kovalenko, Pavel, Parrino, Janie, Boyapati, Anita, Xu, Christine, van Hoogstraten, Hubert, Ishii, Tomonori, Davis, John D., DiCioccio, A. Thomas
Publicado 2020

Sarilumab monotherapy vs sarilumab and methotrexate combination therapy in patients with rheumatoid arthritis

por Burmester, Gerd R, Bykerk, Vivian P, Buch, Maya H, Tanaka, Yoshiya, Kameda, Hideto, Praestgaard, Amy, van Hoogstraten, Hubert, Fernandez-Nebro, Antonio, Huizinga, Thomas
Publicado 2021

Evaluation of the efficacy and safety of sarilumab combination therapy in patients with rheumatoid arthritis with inadequate response to conventional disease-modifying antirheumati...

por Choy, Ernest, Freemantle, Nick, Proudfoot, Clare, Chen, Chieh-I, Pollissard, Laurence, Kuznik, Andreas, Van Hoogstraten, Hubert, Mangan, Erin, Carita, Paulo, Huynh, Thi-Minh-Thao
Publicado 2019

Indirect Treatment Comparison of the Efficacy and Safety of Sarilumab Monotherapy in Rheumatoid Arthritis Patients with Inadequate Response to Conventional Disease-Modifying Antirh...

por Choy, Ernest, Freemantle, Nick, Proudfoot, Clare, Chen, Chieh-I, Pollissard, Laurence, Kuznik, Andreas, van Hoogstraten, Hubert, Mangan, Erin, Carita, Paulo, Huynh, Thi-Minh-Thao
Publicado 2019

Efficacy and safety of sarilumab in combination with csDMARDs or as monotherapy in subpopulations of patients with moderately to severely active rheumatoid arthritis in three phase...

por Genovese, Mark C., Fleischmann, Roy, Kivitz, Alan, Lee, Eun-Bong, van Hoogstraten, Hubert, Kimura, Toshio, St John, Gregory, Mangan, Erin K., Burmester, Gerd R.
Publicado 2020

Immunogenicity of Sarilumab Monotherapy in Patients with Rheumatoid Arthritis Who Were Inadequate Responders or Intolerant to Disease-Modifying Antirheumatic Drugs

por Wells, Alvin F., Parrino, Janie, Mangan, Erin K., Paccaly, Anne, Lin, Yong, Xu, Christine, Fan, Chunpeng, Graham, Neil M. H., van Hoogstraten, Hubert, Torri, Albert
Publicado 2019

Safety and tolerability of subcutaneous sarilumab and intravenous tocilizumab in patients with rheumatoid arthritis

por Emery, Paul, Rondon, Juan, Parrino, Janie, Lin, Yong, Pena-Rossi, Claudia, van Hoogstraten, Hubert, Graham, Neil M H, Liu, Nancy, Paccaly, Anne, Wu, Richard, Spindler, Alberto
Publicado 2019

Clinical Efficacy of Sarilumab Versus Upadacitinib Over 12 weeks: An Indirect Treatment Comparison

por Huizinga, Thomas, Choy, Ernest, Praestgaard, Amy, van Hoogstraten, Hubert, LaFontaine, Patrick R., Guyot, Patricia, Aletaha, Daniel, Müller-Ladner, Ulf, Tanaka, Yoshiya, Curtis, Jeffrey R., Fleischmann, Roy
Publicado 2023

Sarilumab and adalimumab differential effects on bone remodelling and cardiovascular risk biomarkers, and predictions of treatment outcomes

por Gabay, Cem, Burmester, Gerd R., Strand, Vibeke, Msihid, Jérôme, Zilberstein, Moshe, Kimura, Toshio, van Hoogstraten, Hubert, Boklage, Susan H., Sadeh, Jonathan, Graham, Neil M. H., Boyapati, Anita
Publicado 2020

Sarilumab plus methotrexate improves patient-reported outcomes in patients with active rheumatoid arthritis and inadequate responses to methotrexate: results of a phase III trial

por Strand, Vibeke, Kosinski, Mark, Chen, Chieh-I, Joseph, George, Rendas-Baum, Regina, Graham, Neil M. H., van Hoogstraten, Hubert, Bayliss, Martha, Fan, Chunpeng, Huizinga, Tom, Genovese, Mark C.
Publicado 2016

Efficacy and safety of sarilumab monotherapy versus adalimumab monotherapy for the treatment of patients with active rheumatoid arthritis (MONARCH): a randomised, double-blind, par...

por Burmester, Gerd R, Lin, Yong, Patel, Rahul, van Adelsberg, Janet, Mangan, Erin K, Graham, Neil M H, van Hoogstraten, Hubert, Bauer, Deborah, Ignacio Vargas, Juan, Lee, Eun Bong
Publicado 2017

Sarilumab and Nonbiologic Disease‐Modifying Antirheumatic Drugs in Patients With Active Rheumatoid Arthritis and Inadequate Response or Intolerance to Tumor Necrosis Factor Inhibit...

por Fleischmann, Roy, van Adelsberg, Janet, Lin, Yong, Castelar‐Pinheiro, Geraldo da Rocha, Brzezicki, Jan, Hrycaj, Pawel, Graham, Neil M. H., van Hoogstraten, Hubert, Bauer, Deborah, Burmester, Gerd R.
Publicado 2017

Correction to: Identification of a Rule to Predict Response to Sarilumab in Patients with Rheumatoid Arthritis Using Machine Learning and Clinical Trial Data

por Rehberg, Markus, Giegerich, Clemens, Praestgaard, Amy, van Hoogstraten, Hubert, Iglesias-Rodriguez, Melitza, Curtis, Jeffrey R., Gottenberg, Jacques-Eric, Schwarting, Andreas, Castañeda, Santos, Rubbert-Roth, Andrea, Choy, Ernest H. S.
Publicado 2021

Identification of a Rule to Predict Response to Sarilumab in Patients with Rheumatoid Arthritis Using Machine Learning and Clinical Trial Data

por Rehberg, Markus, Giegerich, Clemens, Praestgaard, Amy, van Hoogstraten, Hubert, Iglesias-Rodriguez, Melitza, Curtis, Jeffrey R., Gottenberg, Jacques-Eric, Schwarting, Andreas, Castañeda, Santos, Rubbert-Roth, Andrea, Choy, Ernest H. S.
Publicado 2021