Estimation of Activity Related Energy Expenditure and Resting Metabolic Rate in Freely Moving Mice from Indirect Calorimetry Data

por Van Klinken, Jan Bert, van den Berg, Sjoerd A. A., Havekes, Louis M., Willems Van Dijk, Ko
Publicado 2012

Clustered Mendelian randomization analyses identify distinct and opposing pathways in the association between genetically influenced insulin-like growth factor-1 and type 2 diabete...

por Wang, Wenyi, Tesfay, Ephrem Baraki, van Klinken, Jan Bert, Willems van Dijk, Ko, Bartke, Andrzej, van Heemst, Diana, Noordam, Raymond
Publicado 2022

Adverse generational changes in obesity development converge at midlife without increased cardiometabolic risk

por Ibi, Dorina, Rietman, M. Liset, Picavet, H. S. J., van Klinken, Jan Bert, van Dijk, Ko Willems, Dollé, Martijn E. T., Verschuren, W.M. Monique
Publicado 2021

Pyruvate dehydrogenase complex plays a central role in brown adipocyte energy expenditure and fuel utilization during short-term beta-adrenergic activation

por Held, Ntsiki M., Kuipers, Eline N., van Weeghel, Michel, van Klinken, Jan Bert, Denis, Simone W., Lombès, Marc, Wanders, Ronald J., Vaz, Frédéric M., Rensen, Patrick C. N., Verhoeven, Arthur J., Boon, Mariëtte R., Houtkooper, Riekelt H.
Publicado 2018

Automated workflow-based exploitation of pathway databases provides new insights into genetic associations of metabolite profiles

por Dharuri, Harish, Henneman, Peter, Demirkan, Ayse, van Klinken, Jan Bert, Mook-Kanamori, Dennis Owen, Wang-Sattler, Rui, Gieger, Christian, Adamski, Jerzy, Hettne, Kristina, Roos, Marco, Suhre, Karsten, Van Duijn, Cornelia M, van Dijk, Ko Willems, 't Hoen, Peter AC
Publicado 2013

Postprandial metabolite profiles associated with type 2 diabetes clearly stratify individuals with impaired fasting glucose

por Li-Gao, Ruifang, de Mutsert, Renée, Rensen, Patrick C. N., van Klinken, Jan Bert, Prehn, Cornelia, Adamski, Jerzy, van Hylckama Vlieg, Astrid, den Heijer, Martin, le Cessie, Saskia, Rosendaal, Frits R., Willems van Dijk, Ko, Mook-Kanamori, Dennis O.
Publicado 2017

Insight in Genome-Wide Association of Metabolite Quantitative Traits by Exome Sequence Analyses

por Demirkan, Ayşe, Henneman, Peter, Verhoeven, Aswin, Dharuri, Harish, Amin, Najaf, van Klinken, Jan Bert, Karssen, Lennart C., de Vries, Boukje, Meissner, Axel, Göraler, Sibel, van den Maagdenberg, Arn M. J. M., Deelder, André M., C ’t Hoen, Peter A., van Duijn, Cornelia M., van Dijk, Ko Willems
Publicado 2015

Angiopoietin-like 4 governs diurnal lipoprotein lipase activity in brown adipose tissue

por van Eenige, Robin, In het Panhuis, Wietse, Schönke, Milena, Jouffe, Céline, Devilee, Thomas H., Siebeler, Ricky, Streefland, Trea C.M., Sips, Hetty C.M., Pronk, Amanda C.M., Vorderman, Ruben H.P., Mei, Hailiang, van Klinken, Jan Bert, van Weeghel, Michel, Uhlenhaut, Nina H., Kersten, Sander, Rensen, Patrick C.N., Kooijman, Sander
Publicado 2022

The effect of mirabegron on energy expenditure and brown adipose tissue in healthy lean South Asian and Europid men

por Nahon, Kimberly J., Janssen, Laura G. M., Sardjoe Mishre, Aashley S. D., Bilsen, Manu P., van der Eijk, Jari A., Botani, Kani, Overduin, Lisanne A., Ruiz, Jonatan R., Burakiewicz, Jedrzej, Dzyubachyk, Oleh, Webb, Andrew G., Kan, Hermien E., Berbée, Jimmy F. P., van Klinken, Jan‐Bert, van Dijk, Ko Willems, van Weeghel, Michel, Vaz, Frédéric M., Coskun, Tamer, Jazet, Ingrid M., Kooijman, Sander, Martinez‐Tellez, Borja, Boon, Mariëtte R., Rensen, Patrick C. N.
Publicado 2020

Deleterious variants in CRLS1 lead to cardiolipin deficiency and cause an autosomal recessive multi-system mitochondrial disease

por Lee, Richard G, Balasubramaniam, Shanti, Stentenbach, Maike, Kralj, Tom, McCubbin, Tim, Padman, Benjamin, Smith, Janine, Riley, Lisa G, Priyadarshi, Archana, Peng, Liuyu, Nuske, Madison R, Webster, Richard, Peacock, Ken, Roberts, Philip, Stark, Zornitza, Lemire, Gabrielle, Ito, Yoko A, Boycott, Kym M, Geraghty, Michael T, van Klinken, Jan Bert, Ferdinandusse, Sacha, Zhou, Ying, Walsh, Rebecca, Marcellin, Esteban, Thorburn, David R, Rosciolli, Tony, Fletcher, Janice, Rackham, Oliver, Vaz, Frédéric M, Reid, Gavin E, Filipovska, Aleksandra
Publicado 2022

A metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals

por Deelen, Joris, Kettunen, Johannes, Fischer, Krista, van der Spek, Ashley, Trompet, Stella, Kastenmüller, Gabi, Boyd, Andy, Zierer, Jonas, van den Akker, Erik B., Ala-Korpela, Mika, Amin, Najaf, Demirkan, Ayse, Ghanbari, Mohsen, van Heemst, Diana, Ikram, M. Arfan, van Klinken, Jan Bert, Mooijaart, Simon P., Peters, Annette, Salomaa, Veikko, Sattar, Naveed, Spector, Tim D., Tiemeier, Henning, Verhoeven, Aswin, Waldenberger, Melanie, Würtz, Peter, Davey Smith, George, Metspalu, Andres, Perola, Markus, Menni, Cristina, Geleijnse, Johanna M., Drenos, Fotios, Beekman, Marian, Jukema, J. Wouter, van Duijn, Cornelia M., Slagboom, P. Eline
Publicado 2019