Allergen-specific subcutaneous immunotherapy in allergic asthma: immunologic mechanisms and improvement

por Taher, Yousef A., Henricks, Paul A.J., van Oosterhout, Antoon J.M.
Publicado 2010

TLR-2 Activation Induces Regulatory T Cells and Long-Term Suppression of Asthma Manifestations in Mice

por Nawijn, Martijn C., Motta, Alexandre C., Gras, Renée, Shirinbak, Soheila, Maazi, Hadi, van Oosterhout, Antoon J. M.
Publicado 2013

Stimulation of allergen-loaded macrophages by TLR9-ligand potentiates IL-10-mediated suppression of allergic airway inflammation in mice

por Vissers, Joost LM, van Esch, Betty CAM, Jeurink, Prescilla V, Hofman, Gerard A, van Oosterhout, Antoon JM
Publicado 2004

Role of aberrant metalloproteinase activity in the pro-inflammatory phenotype of bronchial epithelium in COPD

por Heijink, Irene H, Brandenburg, Simone M, Noordhoek, Jacobien A, Slebos, Dirk-Jan, Postma, Dirkje S, van Oosterhout, Antoon J
Publicado 2011

1,25(OH)(2)VitD3 supplementation enhances suppression of grass pollen-induced allergic asthma by subcutaneous and sublingual immunotherapy in a mouse model

por Hesse, Laura, Petersen, Arjen H., Oude Elberink, Joanne N. G., van Oosterhout, Antoon J. M., Nawijn, Martijn C.
Publicado 2020

GITR signaling potentiates airway hyperresponsiveness by enhancing Th2 cell activity in a mouse model of asthma

por Motta, Alexandre C, Vissers, Joost LM, Gras, Renée, Van Esch, Betty CAM, Van Oosterhout, Antoon JM, Nawijn, Martijn C
Publicado 2009

Protease-Activated Receptor-2 Activation Contributes to House Dust Mite-Induced IgE Responses in Mice

por Post, Sijranke, Heijink, Irene H., Petersen, Arjen H., de Bruin, Harold G., van Oosterhout, Antoon J. M., Nawijn, Martijn C.
Publicado 2014

High dose vitamin D(3) empowers effects of subcutaneous immunotherapy in a grass pollen-driven mouse model of asthma

por Hesse, Laura, van Ieperen, N., Petersen, Arjen H., Elberink, J. N. G. Oude, van Oosterhout, Antoon J. M., Nawijn, Martijn C.
Publicado 2020

Critical role of aldehydes in cigarette smoke-induced acute airway inflammation

por van der Toorn, Marco, Slebos, Dirk-Jan, de Bruin, Harold G, Gras, Renee, Rezayat, Delaram, Jorge, Lucie, Sandra, Koen, van Oosterhout, Antoon JM
Publicado 2013

Neutrophilic Asthma Is Associated With Smoking, High Numbers of IRF5+, and Low Numbers of IL10+ Macrophages

por Turan, Nil, van der Veen, T. Anienke, Draijer, Christina, Fattahi, Fatemeh, ten Hacken, Nick H., Timens, Wim, van Oosterhout, Antoon J., van den Berge, Maarten, Melgert, Barbro N.
Publicado 2021

Change in inflammation in out-patient COPD patients from stable phase to a subsequent exacerbation

por Bathoorn, Erik, Liesker, Jeroen JW, Postma, Dirkje S, Koëter, Gerard H, van der Toorn, Marco, van der Heide, Sicco, Ross, H Alec, van Oosterhout, Antoon JM, Kerstjens, Huib AM
Publicado 2009

Increased activation of blood neutrophils after cigarette smoking in young individuals susceptible to COPD

por Hoonhorst, Susan JM, Timens, Wim, Koenderman, Leo, Lo Tam Loi, Adèle T, Lammers, Jan-Willem J, Boezen, H Marike, van Oosterhout, Antoon JM, Postma, Dirkje S, ten Hacken, Nick HT
Publicado 2014

BET Bromodomain Inhibitor iBET151 Impedes Human ILC2 Activation and Prevents Experimental Allergic Lung Inflammation

por Kerscher, Bernhard, Barlow, Jillian L., Rana, Batika M., Jolin, Helen E., Gogoi, Mayuri, Bartholomew, Michelle A., Jhamb, Deepali, Pandey, Ashutosh, Tough, David F., van Oosterhout, Antoon J. M., McKenzie, Andrew N. J.
Publicado 2019

Profiling of H3K27Ac Reveals the Influence of Asthma on the Epigenome of the Airway Epithelium

por McErlean, Peter, Kelly, Audrey, Dhariwal, Jaideep, Kirtland, Max, Watson, Julie, Ranz, Ismael, Smith, Janet, Saxena, Alka, Cousins, David J., Van Oosterhout, Antoon, Solari, Roberto, Edwards, Michael R., Johnston, Sebastian L., Lavender, Paul
Publicado 2020

Acute and chronic inflammatory responses induced by smoking in individuals susceptible and non-susceptible to development of COPD: from specific disease phenotyping towards novel t...

por Lo Tam Loi, Adèle T, Hoonhorst, Susan J M, Franciosi, Lorenza, Bischoff, Rainer, Hoffmann, Roland F, Heijink, Irene, van Oosterhout, Antoon J M, Boezen, H Marike, Timens, Wim, Postma, Dirkje S, Lammers, Jan-Willem, Koenderman, Leo, ten Hacken, Nick H T
Publicado 2013

Prolonged cigarette smoke exposure alters mitochondrial structure and function in airway epithelial cells

por Hoffmann, Roland F, Zarrintan, Sina, Brandenburg, Simone M, Kol, Arjan, de Bruin, Harold G, Jafari, Shabnam, Dijk, Freark, Kalicharan, Dharamdajal, Kelders, Marco, Gosker, Harry R, ten Hacken, Nick HT, van der Want, Johannes J, van Oosterhout, Antoon JM, Heijink, Irene H
Publicado 2013

Mouse Protocadherin-1 Gene Expression Is Regulated by Cigarette Smoke Exposure In Vivo

por Koning, Henk, van Oosterhout, Antoon J. M., Brouwer, Uilke, den Boef, Lisette E., Gras, Renée, Reinders-Luinge, Marjan, Brandsma, Corry-Anke, van der Toorn, Marco, Hylkema, Machteld N., Willemse, Brigitte W. M., Sayers, Ian, Koppelman, Gerard H., Nawijn, Martijn C.
Publicado 2014

Advanced glycation endproducts and their receptor in different body compartments in COPD

por Hoonhorst, Susan J. M., Lo Tam Loi, Adèle T., Pouwels, Simon D., Faiz, Alen, Telenga, Eef D., van den Berge, Maarten, Koenderman, Leo, Lammers, Jan-Willem J., Boezen, H. Marike, van Oosterhout, Antoon J. M., Lodewijk, Monique E., Timens, Wim, Postma, Dirkje S., ten Hacken, Nick H. T.
Publicado 2016

Glycogen synthase kinase-3β modulation of glucocorticoid responsiveness in COPD

por Ngkelo, Anta, Hoffmann, Roland F., Durham, Andrew L., Marwick, John A., Brandenburg, Simone M., de Bruin, Harold G., Jonker, Marnix R., Rossios, Christos, Tsitsiou, Eleni, Caramori, Gaetano, Contoli, Marco, Casolari, Paolo, Monaco, Francesco, Andò, Filippo, Speciale, Giuseppe, Kilty, Iain, Chung, Kian F., Papi, Alberto, Lindsay, Mark A., ten Hacken, Nick H. T., van den Berge, Maarten, Timens, Wim, Barnes, Peter J., van Oosterhout, Antoon J., Adcock, Ian M., Kirkham, Paul A., Heijink, Irene H.
Publicado 2015