High-affinity CD16-polymorphism and Fc-engineered antibodies enable activity of CD16-chimeric antigen receptor-modified T cells for cancer therapy

por Rataj, Felicitas, Jacobi, Severin J., Stoiber, Stefan, Asang, Florian, Ogonek, Justyna, Tokarew, Nicholas, Cadilha, Bruno L., van Puijenbroek, Erwin, Heise, Constanze, Duewell, Peter, Endres, Stefan, Klein, Christian, Kobold, Sebastian
Publicado 2018

Fc gamma receptor IIIb binding of individual antibody proteoforms resolved by affinity chromatography–mass spectrometry

por Lippold, Steffen, Knaupp, Alexander, de Ru, Arnoud H., Tjokrodirijo, Rayman T. N., van Veelen, Peter A., van Puijenbroek, Erwin, de Taeye, Steven W., Reusch, Dietmar, Vidarsson, Gestur, Wuhrer, Manfred, Schlothauer, Tilman, Falck, David
Publicado 2021

Cergutuzumab amunaleukin (CEA-IL2v), a CEA-targeted IL-2 variant-based immunocytokine for combination cancer immunotherapy: Overcoming limitations of aldesleukin and conventional I...

por Klein, Christian, Waldhauer, Inja, Nicolini, Valeria G., Freimoser-Grundschober, Anne, Nayak, Tapan, Vugts, Danielle J., Dunn, Claire, Bolijn, Marije, Benz, Jörg, Stihle, Martine, Lang, Sabine, Roemmele, Michaele, Hofer, Thomas, van Puijenbroek, Erwin, Wittig, David, Moser, Samuel, Ast, Oliver, Brünker, Peter, Gorr, Ingo H., Neumann, Sebastian, de Vera Mudry, Maria Cristina, Hinton, Heather, Crameri, Flavio, Saro, Jose, Evers, Stefan, Gerdes, Christian, Bacac, Marina, van Dongen, Guus, Moessner, Ekkehard, Umaña, Pablo
Publicado 2017

Simlukafusp alfa (FAP-IL2v) immunocytokine is a versatile combination partner for cancer immunotherapy

por Waldhauer, Inja, Gonzalez-Nicolini, Valeria, Freimoser-Grundschober, Anne, Nayak, Tapan K, Fahrni, Linda, Hosse, Ralf J., Gerrits, Danny, Geven, Edwin J. W., Sam, Johannes, Lang, Sabine, Bommer, Esther, Steinhart, Virginie, Husar, Elisabeth, Colombetti, Sara, Van Puijenbroek, Erwin, Neubauer, Markus, Cline, J. Mark, Garg, Pradeep K., Dugan, Gregory, Cavallo, Federica, Acuna, Gonzalo, Charo, Jehad, Teichgräber, Volker, Evers, Stefan, Boerman, Otto C., Bacac, Marina, Moessner, Ekkehard, Umaña, Pablo, Klein, Christian
Publicado 2021