CD44 drives aggressiveness and chemoresistance of a metastatic human osteosarcoma xenograft model

por Mayr, Lisa, Pirker, Christine, Lötsch, Daniela, Van Schoonhoven, Sushilla, Windhager, Reinhard, Englinger, Bernhard, Berger, Walter, Kubista, Bernd
Publicado 2017

Distinct activity of the bone-targeted gallium compound KP46 against osteosarcoma cells - synergism with autophagy inhibition

por Kubista, Bernd, Schoefl, Thomas, Mayr, Lisa, van Schoonhoven, Sushilla, Heffeter, Petra, Windhager, Reinhard, Keppler, Bernhard K., Berger, Walter
Publicado 2017

EGFR is not a major driver for osteosarcoma cell growth in vitro but contributes to starvation and chemotherapy resistance

por Sevelda, Florian, Mayr, Lisa, Kubista, Bernd, Lötsch, Daniela, van Schoonhoven, Sushilla, Windhager, Reinhard, Pirker, Christine, Micksche, Michael, Berger, Walter
Publicado 2015

Another step toward DNA selective targeting: Ni(II) and Cu(II) complexes of a Schiff base ligand able to bind gene promoter G-quadruplexes

por Terenzi, Alessio, Lötsch, Daniela, van Schoonhoven, Sushilla, Roller, Alexander, Kowol, Christian R., Berger, Walter, Keppler, Bernhard K., Barone, Giampaolo
Publicado 2016

Loss of phosphodiesterase 4D mediates acquired triapine resistance via Epac-Rap1-Integrin signaling

por Miklos, Walter, Heffeter, Petra, Pirker, Christine, Hager, Sonja, Kowol, Christian R., van Schoonhoven, Sushilla, Stojanovic, Mirjana, Keppler, Bernhard K., Berger, Walter
Publicado 2016

Chronic arsenic trioxide exposure leads to enhanced aggressiveness via Met oncogene addiction in cancer cells

por Kryeziu, Kushtrim, Pirker, Christine, Englinger, Bernhard, van Schoonhoven, Sushilla, Spitzwieser, Melanie, Mohr, Thomas, Körner, Wilfried, Weinmüllner, Regina, Tav, Koray, Grillari, Johannes, Cichna-Markl, Margit, Berger, Walter, Heffeter, Petra
Publicado 2016

The Natural Fungal Metabolite Beauvericin Exerts Anticancer Activity In Vivo: A Pre-Clinical Pilot Study

por Heilos, Daniela, Rodríguez-Carrasco, Yelko, Englinger, Bernhard, Timelthaler, Gerald, van Schoonhoven, Sushilla, Sulyok, Michael, Boecker, Simon, Süssmuth, Roderich D., Heffeter, Petra, Lemmens-Gruber, Rosa, Dornetshuber-Fleiss, Rita, Berger, Walter
Publicado 2017

Landomycins as glutathione-depleting agents and natural fluorescent probes for cellular Michael adduct-dependent quinone metabolism

por Terenzi, Alessio, La Franca, Mery, van Schoonhoven, Sushilla, Panchuk, Rostyslav, Martínez, Álvaro, Heffeter, Petra, Gober, Redding, Pirker, Christine, Vician, Petra, Kowol, Christian R., Stoika, Rostyslav, Salassa, Luca, Rohr, Jürgen, Berger, Walter
Publicado 2021

Intrinsic fluorescence of the clinically approved multikinase inhibitor nintedanib reveals lysosomal sequestration as resistance mechanism in FGFR-driven lung cancer

por Englinger, Bernhard, Kallus, Sebastian, Senkiv, Julia, Heilos, Daniela, Gabler, Lisa, van Schoonhoven, Sushilla, Terenzi, Alessio, Moser, Patrick, Pirker, Christine, Timelthaler, Gerald, Jäger, Walter, Kowol, Christian R., Heffeter, Petra, Grusch, Michael, Berger, Walter
Publicado 2017

Acquired nintedanib resistance in FGFR1-driven small cell lung cancer: role of endothelin-A receptor-activated ABCB1 expression

por Englinger, Bernhard, Lötsch, Daniela, Pirker, Christine, Mohr, Thomas, van Schoonhoven, Sushilla, Boidol, Bernd, Lardeau, Charles-Hugues, Spitzwieser, Melanie, Szabó, Pál, Heffeter, Petra, Lang, Irene, Cichna-Markl, Margit, Grasl-Kraupp, Bettina, Marian, Brigitte, Grusch, Michael, Kubicek, Stefan, Szakács, Gergely, Berger, Walter
Publicado 2016

Altered membrane rigidity via enhanced endogenous cholesterol synthesis drives cancer cell resistance to destruxins

por Heilos, Daniela, Röhrl, Clemens, Pirker, Christine, Englinger, Bernhard, Baier, Dina, Mohr, Thomas, Schwaiger, Michaela, Iqbal, Shahid Muhammad, van Schoonhoven, Sushilla, Klavins, Kristaps, Eberhart, Tanja, Windberger, Ursula, Taibon, Judith, Sturm, Sonja, Stuppner, Hermann, Koellensperger, Gunda, Dornetshuber-Fleiss, Rita, Jäger, Walter, Lemmens-Gruber, Rosa, Berger, Walter
Publicado 2018

TERT expression is susceptible to BRAF and ETS-factor inhibition in BRAF(V600E)/TERT promoter double-mutated glioma

por Gabler, Lisa, Lötsch, Daniela, Kirchhofer, Dominik, van Schoonhoven, Sushilla, Schmidt, Hannah M., Mayr, Lisa, Pirker, Christine, Neumayer, Katharina, Dinhof, Carina, Kastler, Lucia, Azizi, Amedeo A., Dorfer, Christian, Czech, Thomas, Haberler, Christine, Peyrl, Andreas, Kumar, Rajiv, Slavc, Irene, Spiegl-Kreinecker, Sabine, Gojo, Johannes, Berger, Walter
Publicado 2019

Fibroblast growth factor receptor 4 promotes glioblastoma progression: a central role of integrin-mediated cell invasiveness

por Gabler, Lisa, Jaunecker, Carola Nadine, Katz, Sonja, van Schoonhoven, Sushilla, Englinger, Bernhard, Pirker, Christine, Mohr, Thomas, Vician, Petra, Stojanovic, Mirjana, Woitzuck, Valentin, Laemmerer, Anna, Kirchhofer, Dominik, Mayr, Lisa, LaFranca, Mery, Erhart, Friedrich, Grissenberger, Sarah, Wenninger-Weinzierl, Andrea, Sturtzel, Caterina, Kiesel, Barbara, Lang, Alexandra, Marian, Brigitte, Grasl-Kraupp, Bettina, Distel, Martin, Schüler, Julia, Gojo, Johannes, Grusch, Michael, Spiegl-Kreinecker, Sabine, Donoghue, Daniel J., Lötsch, Daniela, Berger, Walter
Publicado 2022