Fusion of Wild-Type Mesoangioblasts with Myotubes of mtDNA Mutation Carriers Leads to a Proportional Reduction in mtDNA Mutation Load

por Zelissen, Ruby, Ahmadian, Somaieh, Montilla-Rojo, Joaquin, Timmer, Erika, Ummelen, Monique, Hopman, Anton, Smeets, Hubert, van Tienen, Florence
Publicado 2023

Smad1/5/8 are myogenic regulators of murine and human mesoangioblasts

por Costamagna, Domiziana, Quattrocelli, Mattia, van Tienen, Florence, Umans, Lieve, de Coo, Irineus F. M., Zwijsen, An, Huylebroeck, Danny, Sampaolesi, Maurilio
Publicado 2016

Tfam Knockdown Results in Reduction of mtDNA Copy Number, OXPHOS Deficiency and Abnormalities in Zebrafish Embryos

por Otten, Auke B. C., Kamps, Rick, Lindsey, Patrick, Gerards, Mike, Pendeville-Samain, Hélène, Muller, Marc, van Tienen, Florence H. J., Smeets, Hubert J. M.
Publicado 2020

Healthy, mtDNA-mutation free mesoangioblasts from mtDNA patients qualify for autologous therapy

por van Tienen, Florence, Zelissen, Ruby, Timmer, Erika, van Gisbergen, Marike, Lindsey, Patrick, Quattrocelli, Mattia, Sampaolesi, Maurilio, Mulder-den Hartog, Elvira, de Coo, Irenaeus, Smeets, Hubert
Publicado 2019

Myogenic Cell Transplantation in Genetic and Acquired Diseases of Skeletal Muscle

por Boyer, Olivier, Butler-Browne, Gillian, Chinoy, Hector, Cossu, Giulio, Galli, Francesco, Lilleker, James B., Magli, Alessandro, Mouly, Vincent, Perlingeiro, Rita C. R., Previtali, Stefano C., Sampaolesi, Maurilio, Smeets, Hubert, Schoewel-Wolf, Verena, Spuler, Simone, Torrente, Yvan, Van Tienen, Florence
Publicado 2021

Selection and Characterization of Palmitic Acid Responsive Patients with an OXPHOS Complex I Defect

por Theunissen, Tom E. J., Gerards, Mike, Hellebrekers, Debby M. E. I., van Tienen, Florence H., Kamps, Rick, Sallevelt, Suzanne C. E. H., Hartog, Elvira N. M. M.-D., Scholte, Hans R., Verdijk, Robert M., Schoonderwoerd, Kees, de Coo, Irenaeus F. M., Szklarczyk, Radek, Smeets, Hubert J. M.
Publicado 2017

Natural history, outcome measures and trial readiness in LAMA2-related muscular dystrophy and SELENON-related myopathy in children and adults: protocol of the LAST STRONG study

por Bouman, Karlijn, Groothuis, Jan T., Doorduin, Jonne, van Alfen, Nens, Udink ten Cate, Floris E. A., van den Heuvel, Frederik M. A., Nijveldt, Robin, van Tilburg, Willem C. M., Buckens, Stan C. F. M., Dittrich, Anne T. M., Draaisma, Jos M. T., Janssen, Mirian C. H., Kamsteeg, Erik-Jan, van Kleef, Esmee S. B., Koene, Saskia, Smeitink, Jan A. M., Küsters, Benno, van Tienen, Florence H. J., Smeets, Hubert J. M., van Engelen, Baziel G. M., Erasmus, Corrie E., Voermans, Nicol C.
Publicado 2021