Shared Genetic Contribution of Type 2 Diabetes and Cardiovascular Disease: Implications for Prognosis and Treatment

por Strawbridge, Rona J., van Zuydam, Natalie R.
Publicado 2018

Intestinal Absorption of FITC-Dextrans and Macromolecular Model Drugs in the Rat Intestinal Instillation Model

por Berg, Staffan, Suljovic, Denny, Kärrberg, Lillevi, Englund, Maria, Bönisch, Heiko, Karlberg, Ida, Van Zuydam, Natalie, Abrahamsson, Bertil, Hugerth, Andreas Martin, Davies, Nigel, Bergström, Christel A. S.
Publicado 2022

The sodium glucose co-transporter 2 inhibitor dapagliflozin ameliorates the fluid-retaining effect of the endothelin A receptor antagonist zibotentan

por Veenit, Vandana, Heerspink, Hiddo J L, Ahlström, Christine, Greasley, Peter J, Skritic, Stanko, van Zuydam, Natalie, Kohan, Donald E, Hansen, Pernille B L, Menzies, Robert I
Publicado 2023

Impact of Intestinal Concentration and Colloidal Structure on the Permeation-Enhancing Efficiency of Sodium Caprate in the Rat

por Berg, Staffan, Kärrberg, Lillevi, Suljovic, Denny, Seeliger, Frank, Söderberg, Magnus, Perez-Alcazar, Marta, Van Zuydam, Natalie, Abrahamsson, Bertil, Hugerth, Andreas M, Davies, Nigel, Bergström, Christel A. S.
Publicado 2021

Genetic variants predicting left ventricular hypertrophy in a diabetic population: a Go-DARTS study including meta-analysis

por Parry, Helen M, Donnelly, Louise A, Van Zuydam, Natalie, Doney, Alexander SF, Elder, Douglas HJ, Morris, Andrew D, Struthers, Alan D, Palmer, Colin NA, Lang, Chim C
Publicado 2013

Association of Genetic Variant at Chromosome 12q23.1 With Neuropathic Pain Susceptibility

por Veluchamy, Abirami, Hébert, Harry L., van Zuydam, Natalie R., Pearson, Ewan R., Campbell, Archie, Hayward, Caroline, Meng, Weihua, McCarthy, Mark I., Bennett, David L. H., Palmer, Colin N. A., Smith, Blair H.
Publicado 2021

Identification of 371 genetic variants for age at first sex and birth linked to externalising behaviour

por Mills, Melinda C., Tropf, Felix C., Brazel, David M., van Zuydam, Natalie, Vaez, Ahmad, Pers, Tune H., Snieder, Harold, Perry, John R.B., Ong, Ken K., den Hoed, Marcel, Barban, Nicola, Day, Felix R.
Publicado 2021

Heritability of variation in glycaemic response to metformin: a genome-wide complex trait analysis

por Zhou, Kaixin, Donnelly, Louise, Yang, Jian, Li, Miaoxin, Deshmukh, Harshal, Van Zuydam, Natalie, Ahlqvist, Emma, Spencer, Chris C, Groop, Leif, Morris, Andrew D, Colhoun, Helen M, Sham, Pak C, McCarthy, Mark I, Palmer, Colin N A, Pearson, Ewan R
Publicado 2014

A variant within the FTO confers susceptibility to diabetic nephropathy in Japanese patients with type 2 diabetes

por Taira, Makiko, Imamura, Minako, Takahashi, Atsushi, Kamatani, Yoichiro, Yamauchi, Toshimasa, Araki, Shin-ichi, Tanaka, Nobue, van Zuydam, Natalie R., Ahlqvist, Emma, Toyoda, Masao, Umezono, Tomoya, Kawai, Koichi, Imanishi, Masahito, Watada, Hirotaka, Suzuki, Daisuke, Maegawa, Hiroshi, Babazono, Tetsuya, Kaku, Kohei, Kawamori, Ryuzo, Groop, Leif C., McCarthy, Mark I., Kadowaki, Takashi, Maeda, Shiro
Publicado 2018

Correction of a urea cycle defect after ex vivo gene editing of human hepatocytes

por Zabulica, Mihaela, Srinivasan, Raghuraman C., Akcakaya, Pinar, Allegri, Gabriella, Bestas, Burcu, Firth, Mike, Hammarstedt, Christina, Jakobsson, Tomas, Jakobsson, Towe, Ellis, Ewa, Jorns, Carl, Makris, Georgios, Scherer, Tanja, Rimann, Nicole, van Zuydam, Natalie R., Gramignoli, Roberto, Forslöw, Anna, Engberg, Susanna, Maresca, Marcello, Rooyackers, Olav, Thöny, Beat, Häberle, Johannes, Rosen, Barry, Strom, Stephen C.
Publicado 2021

A randomised phase 2a study to investigate the effects of blocking interleukin-33 with tozorakimab in patients hospitalised with COVID-19: ACCORD-2

por Wilkinson, Tom, De Soyza, Anthony, Carroll, Miles, Chalmers, James D., Crooks, Michael G., Griffiths, Gareth, Shankar-Hari, Manu, Ho, Ling-Pei, Horsley, Alex, Kell, Chris, Lara, Beatriz, Mishra, Biswa, Moate, Rachel, Page, Clive, Pandya, Hitesh, Raw, Jason, Reid, Fred, Saralaya, Dinesh, Scott, Ian C., Siddiqui, Salman, Ustianowski, Andy, van Zuydam, Natalie, Woodcock, Ashley, Singh, Dave
Publicado 2023

Investigating genotype–phenotype relationship of extreme neuropathic pain disorders in a UK national cohort

por Themistocleous, Andreas C, Baskozos, Georgios, Blesneac, Iulia, Comini, Maddalena, Megy, Karyn, Chong, Sam, Deevi, Sri V V, Ginsberg, Lionel, Gosal, David, Hadden, Robert D M, Horvath, Rita, Mahdi-Rogers, Mohamed, Manzur, Adnan, Mapeta, Rutendo, Marshall, Andrew, Matthews, Emma, McCarthy, Mark I, Reilly, Mary M, Renton, Tara, Rice, Andrew S C, Vale, Tom A, van Zuydam, Natalie, Walker, Suellen M, Woods, Christopher Geoffrey, Bennett, David L H
Publicado 2023

A novel rare CUBN variant and three additional genes identified in Europeans with and without diabetes: results from an exome-wide association study of albuminuria

por Ahluwalia, Tarunveer S., Schulz, Christina-Alexandra, Waage, Johannes, Skaaby, Tea, Sandholm, Niina, van Zuydam, Natalie, Charmet, Romain, Bork-Jensen, Jette, Almgren, Peter, Thuesen, Betina H., Bedin, Mathilda, Brandslund, Ivan, Christensen, Cramer K., Linneberg, Allan, Ahlqvist, Emma, Groop, Per-Henrik, Hadjadj, Samy, Tregouet, David-Alexandre, Jørgensen, Marit E., Grarup, Niels, Pedersen, Oluf, Simons, Matias, Groop, Leif, Orho-Melander, Marju, McCarthy, Mark I., Melander, Olle, Rossing, Peter, Kilpeläinen, Tuomas O., Hansen, Torben
Publicado 2018

Genome-Wide Association Study of Peripheral Artery Disease

por van Zuydam, Natalie R., Stiby, Alexander, Abdalla, Moustafa, Austin, Erin, Dahlström, Emma H., McLachlan, Stela, Vlachopoulou, Efthymia, Ahlqvist, Emma, Di Liao, Chen, Sandholm, Niina, Forsblom, Carol, Mahajan, Anubha, Robertson, Neil R., Rayner, N. William, Lindholm, Eero, Sinisalo, Juha, Perola, Markus, Kallio, Milla, Weiss, Emily, Price, Jackie, Paterson, Andrew, Klein, Barbara, Salomaa, Veikko, Palmer, Colin N.A., Groop, Per-Henrik, Groop, Leif, McCarthy, Mark I., de Andrade, Mariza, Morris, Andrew P., Hopewell, Jemma C., Colhoun, Helen M., Kullo, Iftikhar J.
Publicado 2021

Genome-wide meta-analysis and omics integration identifies novel genes associated with diabetic kidney disease

por Sandholm, Niina, Cole, Joanne B., Nair, Viji, Sheng, Xin, Liu, Hongbo, Ahlqvist, Emma, van Zuydam, Natalie, Dahlström, Emma H., Fermin, Damian, Smyth, Laura J., Salem, Rany M., Forsblom, Carol, Valo, Erkka, Harjutsalo, Valma, Brennan, Eoin P., McKay, Gareth J., Andrews, Darrell, Doyle, Ross, Looker, Helen C., Nelson, Robert G., Palmer, Colin, McKnight, Amy Jayne, Godson, Catherine, Maxwell, Alexander P., Groop, Leif, McCarthy, Mark I., Kretzler, Matthias, Susztak, Katalin, Hirschhorn, Joel N., Florez, Jose C., Groop, Per-Henrik
Publicado 2022

Sex-Specific Effects of Adiponectin on Carotid Intima-Media Thickness and Incident Cardiovascular Disease

por Persson, Jonas, Strawbridge, Rona J, McLeod, Olga, Gertow, Karl, Silveira, Angela, Baldassarre, Damiano, Van Zuydam, Natalie, Shah, Sonia, Fava, Cristiano, Gustafsson, Stefan, Veglia, Fabrizio, Sennblad, Bengt, Larsson, Malin, Sabater-Lleal, Maria, Leander, Karin, Gigante, Bruna, Tabak, Adam, Kivimaki, Mika, Kauhanen, Jussi, Rauramaa, Rainer, Smit, Andries J, Mannarino, Elmo, Giral, Philippe, Humphries, Steve E, Tremoli, Elena, de Faire, Ulf, Lind, Lars, Ingelsson, Erik, Hedblad, Bo, Melander, Olle, Kumari, Meena, Hingorani, Aroon, Morris, Andrew D, Palmer, Colin N A, Lundman, Pia, Öhrvik, John, Söderberg, Stefan, Hamsten, Anders
Publicado 2015

Trans-ethnic Fine Mapping Highlights Kidney-Function Genes Linked to Salt Sensitivity

por Mahajan, Anubha, Rodan, Aylin R., Le, Thu H., Gaulton, Kyle J., Haessler, Jeffrey, Stilp, Adrienne M., Kamatani, Yoichiro, Zhu, Gu, Sofer, Tamar, Puri, Sanjana, Schellinger, Jeffrey N., Chu, Pei-Lun, Cechova, Sylvia, van Zuydam, Natalie, Arnlov, Johan, Flessner, Michael F., Giedraitis, Vilmantas, Heath, Andrew C., Kubo, Michiaki, Larsson, Anders, Lindgren, Cecilia M., Madden, Pamela A.F., Montgomery, Grant W., Papanicolaou, George J., Reiner, Alex P., Sundström, Johan, Thornton, Timothy A., Lind, Lars, Ingelsson, Erik, Cai, Jianwen, Martin, Nicholas G., Kooperberg, Charles, Matsuda, Koichi, Whitfield, John B., Okada, Yukinori, Laurie, Cathy C., Morris, Andrew P., Franceschini, Nora
Publicado 2016

Genetic Predisposition to Coronary Artery Disease in Type 2 Diabetes Mellitus

por van Zuydam, Natalie R., Ladenvall, Claes, Voight, Benjamin F., Strawbridge, Rona J., Fernandez-Tajes, Juan, Rayner, N. William, Robertson, Neil R., Mahajan, Anubha, Vlachopoulou, Efthymia, Goel, Anuj, Kleber, Marcus E., Nelson, Christopher P., Kwee, Lydia Coulter, Esko, Tõnu, Mihailov, Evelin, Mägi, Reedik, Milani, Lili, Fischer, Krista, Kanoni, Stavroula, Kumar, Jitender, Song, Ci, Hartiala, Jaana A., Pedersen, Nancy L., Perola, Markus, Gieger, Christian, Peters, Annette, Qu, Liming, Willems, Sara M., Doney, Alex S.F., Morris, Andrew D., Zheng, Yan, Sesti, Giorgio, Hu, Frank B., Qi, Lu, Laakso, Markku, Thorsteinsdottir, Unnur, Grallert, Harald, van Duijn, Cornelia, Reilly, Muredach P., Ingelsson, Erik, Deloukas, Panos, Kathiresan, Sek, Metspalu, Andres, Shah, Svati H., Sinisalo, Juha, Salomaa, Veikko, Hamsten, Anders, Samani, Nilesh J., März, Winfried, Hazen, Stanley L., Watkins, Hugh, Saleheen, Danish, Morris, Andrew P., Colhoun, Helen M., Groop, Leif, McCarthy, Mark I., Palmer, Colin N.A.
Publicado 2020

Genetic Loci for Retinal Arteriolar Microcirculation

por Sim, Xueling, Jensen, Richard A., Ikram, M. Kamran, Cotch, Mary Frances, Li, Xiaohui, MacGregor, Stuart, Xie, Jing, Smith, Albert Vernon, Boerwinkle, Eric, Mitchell, Paul, Klein, Ronald, Klein, Barbara E. K., Glazer, Nicole L., Lumley, Thomas, McKnight, Barbara, Psaty, Bruce M., de Jong, Paulus T. V. M., Hofman, Albert, Rivadeneira, Fernando, Uitterlinden, Andre G., van Duijn, Cornelia M., Aspelund, Thor, Eiriksdottir, Gudny, Harris, Tamara B., Jonasson, Fridbert, Launer, Lenore J., Attia, John, Baird, Paul N., Harrap, Stephen, Holliday, Elizabeth G., Inouye, Michael, Rochtchina, Elena, Scott, Rodney J., Viswanathan, Ananth, Li, Guo, Smith, Nicholas L., Wiggins, Kerri L., Kuo, Jane Z., Taylor, Kent D., Hewitt, Alex W., Martin, Nicholas G., Montgomery, Grant W., Sun, Cong, Young, Terri L., Mackey, David A., van Zuydam, Natalie R., Doney, Alex S. F., Palmer, Colin N. A., Morris, Andrew D., Rotter, Jerome I., Tai, E. Shyong, Gudnason, Vilmundur, Vingerling, Johannes R., Siscovick, David S., Wang, Jie Jin, Wong, Tien Y.
Publicado 2013

Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE Collaboration): a meta-analysis of genome-wide association studies

por Traylor, Matthew, Farrall, Martin, Holliday, Elizabeth G, Sudlow, Cathie, Hopewell, Jemma C, Cheng, Yu-Ching, Fornage, Myriam, Ikram, M Arfan, Malik, Rainer, Bevan, Steve, Thorsteinsdottir, Unnur, Nalls, Mike A, Longstreth, WT, Wiggins, Kerri L, Yadav, Sunaina, Parati, Eugenio A, DeStefano, Anita L, Worrall, Bradford B, Kittner, Steven J, Khan, Muhammad Saleem, Reiner, Alex P, Helgadottir, Anna, Achterberg, Sefanja, Fernandez-Cadenas, Israel, Abboud, Sherine, Schmidt, Reinhold, Walters, Matthew, Chen, Wei-Min, Ringelstein, E Bernd, O'Donnell, Martin, Ho, Weang Kee, Pera, Joanna, Lemmens, Robin, Norrving, Bo, Higgins, Peter, Benn, Marianne, Sale, Michele, Kuhlenbäumer, Gregor, Doney, Alexander S F, Vicente, Astrid M, Delavaran, Hossein, Algra, Ale, Davies, Gail, Oliveira, Sofia A, Palmer, Colin N A, Deary, Ian, Schmidt, Helena, Pandolfo, Massimo, Montaner, Joan, Carty, Cara, de Bakker, Paul I W, Kostulas, Konstantinos, Ferro, Jose M, van Zuydam, Natalie R, Valdimarsson, Einar, Nordestgaard, Børge G, Lindgren, Arne, Thijs, Vincent, Slowik, Agnieszka, Saleheen, Danish, Paré, Guillaume, Berger, Klaus, Thorleifsson, Gudmar, Hofman, Albert, Mosley, Thomas H, Mitchell, Braxton D, Furie, Karen, Clarke, Robert, Levi, Christopher, Seshadri, Sudha, Gschwendtner, Andreas, Boncoraglio, Giorgio B, Sharma, Pankaj, Bis, Joshua C, Gretarsdottir, Solveig, Psaty, Bruce M, Rothwell, Peter M, Rosand, Jonathan, Meschia, James F, Stefansson, Kari, Dichgans, Martin, Markus, Hugh S
Publicado 2012