High-content imaging-based BAC-GFP toxicity pathway reporters to assess chemical adversity liabilities

por Wink, Steven, Hiemstra, Steven, Herpers, Bram, van de Water, Bob
Publicado 2016

Tumor-induced remote ECM network orientation steers angiogenesis

por Balcioglu, Hayri E., van de Water, Bob, Danen, Erik H. J.
Publicado 2016

ATF6 Is a Critical Determinant of CHOP Dynamics during the Unfolded Protein Response

por Yang, Huan, Niemeijer, Marije, van de Water, Bob, Beltman, Joost B.
Publicado 2020

Highlight report: Launch of a large integrated European in vitro toxicology project: EU-ToxRisk

por Daneshian, Mardas, Kamp, Hennicke, Hengstler, Jan, Leist, Marcel, van de Water, Bob
Publicado 2016

Splicing regulatory factors in breast cancer hallmarks and disease progression

por Koedoot, Esmee, Wolters, Liesanne, van de Water, Bob, Le Dévédec, Sylvia E.
Publicado 2019

Epidermal growth factor receptor signalling in human breast cancer cells operates parallel to estrogen receptor α signalling and results in tamoxifen insensitive proliferation

por Moerkens, Marja, Zhang, Yinghui, Wester, Lynn, van de Water, Bob, Meerman, John HN
Publicado 2014

Targeting the Heterogeneous Genomic Landscape in Triple-Negative Breast Cancer through Inhibitors of the Transcriptional Machinery

por van der Noord, Vera E., van de Water, Bob, Le Dévédec, Sylvia E.
Publicado 2022

An Adverse Outcome Pathway Network for Chemically Induced Oxidative Stress Leading to (Non)genotoxic Carcinogenesis

por Veltman, Christina H. J., Pennings, Jeroen L. A., van de Water, Bob, Luijten, Mirjam
Publicado 2023

Dynamic imaging of adaptive stress response pathway activation for prediction of drug induced liver injury

por Wink, Steven, Hiemstra, Steven W., Huppelschoten, Suzanne, Klip, Janna E., van de Water, Bob
Publicado 2018

Density-Dependent Migration Characteristics of Cancer Cells Driven by Pseudopod Interaction

por Burger, Gerhard A., van de Water, Bob, Le Dévédec, Sylvia E., Beltman, Joost B.
Publicado 2022

Two-Photon Intravital Multicolor Imaging Combined with Inducible Gene Expression to Distinguish Metastatic Behavior of Breast Cancer Cells In Vivo

por Le Dévédec, Sylvia E., Lalai, Reshma, Pont, Chantal, de Bont, Hans, van de Water, Bob
Publicado 2010

Identification of Cisplatin-Regulated Metabolic Pathways in Pluripotent Stem Cells

por von Stechow, Louise, Ruiz-Aracama, Ainhoa, van de Water, Bob, Peijnenburg, Ad, Danen, Erik, Lommen, Arjen
Publicado 2013

Towards an advanced testing strategy for genotoxicity using image-based 2D and 3D HepG2 DNA damage response fluorescent protein reporters

por ter Braak, Bas, Niemeijer, Marije, Wolters, Liesanne, Le Dévédec, Sylvia, Bouwman, Peter, van de Water, Bob
Publicado 2021

FAIR High Content Screening in Bioimaging

por Hosseini, Rohola, Vlasveld, Matthijs, Willemse, Joost, van de Water, Bob, Le Dévédec, Sylvia E., Wolstencroft, Katherine J.
Publicado 2023

Elevated insulin-like growth factor 1 receptor signaling induces antiestrogen resistance through the MAPK/ERK and PI3K/Akt signaling routes

por Zhang, Yinghui, Moerkens, Marja, Ramaiahgari, Sreenivasa, de Bont, Hans, Price, Leo, Meerman, John, van de Water, Bob
Publicado 2011

An improved model to study tumor cell autonomous metastasis programs using MTLn3 cells and the Rag2(−/−) γc(−/−) mouse

por Le Dévédec, Sylvia E., van Roosmalen, Wies, Maria, Naomi, Grimbergen, Max, Pont, Chantal, Lalai, Reshma, van de Water, Bob
Publicado 2009

Automated Analysis of NF-κB Nuclear Translocation Kinetics in High-Throughput Screening

por Di, Zi, Herpers, Bram, Fredriksson, Lisa, Yan, Kuan, van de Water, Bob, Verbeek, Fons J., Meerman, John H. N.
Publicado 2012

Activation of the Nrf2 response by intrinsic hepatotoxic drugs correlates with suppression of NF-κB activation and sensitizes toward TNFα-induced cytotoxicity

por Herpers, Bram, Wink, Steven, Fredriksson, Lisa, Di, Zi, Hendriks, Giel, Vrieling, Harry, de Bont, Hans, van de Water, Bob
Publicado 2015

Co-regulated gene expression of splicing factors as drivers of cancer progression

por Koedoot, Esmee, Smid, Marcel, Foekens, John A., Martens, John W. M., Le Dévédec, Sylvia E., van de Water, Bob
Publicado 2019

Alternative signaling network activation through different insulin receptor family members caused by pro-mitogenic antidiabetic insulin analogues in human mammary epithelial cells

por ter Braak, Bas, Wink, Steven, Koedoot, Esmee, Pont, Chantal, Siezen, Christine, van der Laan, Jan Willem, van de Water, Bob
Publicado 2015