In Vitro Model for Hepatotoxicity Studies Based on Primary Human Hepatocyte Cultivation in a Perfused 3D Bioreactor System

por Knöspel, Fanny, Jacobs, Frank, Freyer, Nora, Damm, Georg, De Bondt, An, van den Wyngaert, Ilse, Snoeys, Jan, Monshouwer, Mario, Richter, Marco, Strahl, Nadja, Seehofer, Daniel, Zeilinger, Katrin
Publicado 2016

Differential gene expression, irrespective of circulating Hepatitis B Surface Antigen levels, between Inactive Carrier and Nucleos(t)ide Analogue-Treated Hepatitis B Virus patients

por Montanari, Noé R, Conceição-Neto, Nádia, Van Den Wyngaert, Ilse, Van Oord, Gertine W, Groothuismink, Zwier M A, Van Tilburg, Sandra, de Man, Robert A, Aerssens, Jeroen, Boonstra, André
Publicado 2020

Effects of microglial depletion and TREM2 deficiency on Aβ plaque burden and neuritic plaque tau pathology in 5XFAD mice

por Delizannis, Argyro Thalia, Nonneman, Annelies, Tsering, Wangchen, De Bondt, An, Van den Wyngaert, Ilse, Zhang, Bin, Meymand, Emily, Olufemi, Modupe F., Koivula, Pyry, Maimaiti, Shaniya, Trojanowski, John Q., Lee, Virginia M.-Y., Brunden, Kurt R.
Publicado 2021

MELK-T1, a small-molecule inhibitor of protein kinase MELK, decreases DNA-damage tolerance in proliferating cancer cells

por Beke, Lijs, Kig, Cenk, Linders, Joannes T. M., Boens, Shannah, Boeckx, An, van Heerde, Erika, Parade, Marc, De Bondt, An, Van den Wyngaert, Ilse, Bashir, Tarig, Ogata, Souichi, Meerpoel, Lieven, Van Eynde, Aleyde, Johnson, Christopher N., Beullens, Monique, Brehmer, Dirk, Bollen, Mathieu
Publicado 2015

Correction: MELK-T1, a small-molecule inhibitor of protein kinase MELK, decreases DNA-damage tolerance in proliferating cancer cells

por Beke, Lijs, Kig, Cenk, Linders, Joannes T. M., Boens, Shannah, Boeckx, An, van Heerde, Erika, Parade, Marc, De Bondt, An, Van den Wyngaert, Ilse, Bashir, Tarig, Ogata, Souichi, Meerpoel, Lieven, Van Eynde, Aleyde, Johnson, Christopher N., Beullens, Monique, Brehmer, Dirk, Bollen, Mathieu
Publicado 2018

A truncated HIV Tat demonstrates potent and specific latency reversal activity

por Van Gulck, Ellen, Pardons, Marion, Nijs, Erik, Verheyen, Nick, Dockx, Koen, Van Den Eynde, Christel, Battivelli, Emilie, Vega, Jerel, Florence, Eric, Autran, Brigitte, Archin, Nancie M., Margolis, David M., Katlama, Christine, Hamimi, Chiraz, Van Den Wyngaert, Ilse, Eyassu, Filmon, Vandekerckhove, Linos, Boden, Daniel
Publicado 2023

Genetically Engineered iPSC-Derived FTDP-17 MAPT Neurons Display Mutation-Specific Neurodegenerative and Neurodevelopmental Phenotypes

por Verheyen, An, Diels, Annick, Reumers, Joke, Van Hoorde, Kirsten, Van den Wyngaert, Ilse, van Outryve d’Ydewalle, Constantin, De Bondt, An, Kuijlaars, Jacobine, De Muynck, Louis, De Hoogt, Ronald, Bretteville, Alexis, Jaensch, Steffen, Buist, Arjan, Cabrera-Socorro, Alfredo, Wray, Selina, Ebneth, Andreas, Roevens, Peter, Royaux, Ines, Peeters, Pieter J.
Publicado 2018

Genetically Engineered iPSC-Derived FTDP-17 MAPT Neurons Display Mutation-Specific Neurodegenerative and Neurodevelopmental Phenotypes

por Verheyen, An, Diels, Annick, Reumers, Joke, Van Hoorde, Kirsten, Van den Wyngaert, Ilse, van Outryve d’Ydewalle, Constantin, De Bondt, An, Kuijlaars, Jacobine, De Muynck, Louis, De Hoogt, Ronald, Bretteville, Alexis, Jaensch, Steffen, Buist, Arjan, Cabrera-Socorro, Alfredo, Wray, Selina, Ebneth, Andreas, Roevens, Peter, Royaux, Ines, Peeters, Pieter J.
Publicado 2019

Tales of 1,008 small molecules: phenomic profiling through live-cell imaging in a panel of reporter cell lines

por Cox, Michael J., Jaensch, Steffen, Van de Waeter, Jelle, Cougnaud, Laure, Seynaeve, Daan, Benalla, Soulaiman, Koo, Seong Joo, Van Den Wyngaert, Ilse, Neefs, Jean-Marc, Malkov, Dmitry, Bittremieux, Mart, Steemans, Margino, Peeters, Pieter J., Wegner, Jörg Kurt, Ceulemans, Hugo, Gustin, Emmanuel, Chong, Yolanda T., Göhlmann, Hinrich W. H.
Publicado 2020